Linkage Disequilibrium (LD)
The Hitchhiking Effect on Linkage Disequilibrium Between Linked Neutral Loci
... strong LD between the neutral ...generating LD has been reiterated in textbooks and publications by many ...of linkage disequilibrium, contrary to our ...increased LD between alleles at ...
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Extent of genome-wide linkage disequilibrium in Australian Holstein-Friesian cattle based on a high-density SNP panel
... of linkage disequilibrium (LD) within a population determines the number of markers that will be required for successful association mapping and marker-assisted ...on LD in cattle reported to ...
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The Extent of Linkage Disequilibrium Caused by Selection on G6PD in Humans
... of linkage disequilibrium (LD) and nucleotide diversity, we resequenced ...long-range LD associated with the A ...and LD suggest that G6PD A is younger than previous age estimates and ...
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LDGIdb: a database of gene interactions inferred from long range strong linkage disequilibrium between pairs of SNPs
... Here we propose a new resource for studies of potential human gene interactions (i.e., LDGIs) based on haplotype data. In LDGIs, the linked genes are located in different chromosomes or LD blocks but are connected ...
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Modeling Linkage Disequilibrium Between a Polymorphic Marker Locus and a Locus Affecting Complex Dichotomous Traits in Natural Populations
... Linkage disequilibrium is an important topic in evolutionary and population ...the linkage disequilibrium analysis to complex ...estimating linkage disequilibrium (LD) ...
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Linkage Disequilibrium as a Signature of Selective Sweeps
... of linkage disequilibrium (LD) is also known to be a strong signature of a selective sweep, we investigate how much statistical power is increased by the inclusion of information regarding ...of ...
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LD-Spline: Mapping SNPs on genotyping platforms to genomic regions using patterns of linkage disequilibrium
... introduce LD-Spline, an efficient data- base procedure for establishing genomic regions that a SNP potentially represents by mining linkage disequilib- rium statistics available from the International ...
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Linkage disequilibrium and within-breed genetic diversity in Iranian Zandi sheep
... of LD reduction in other species ...the LD pattern and high genetic diversity of Zandi sheep, we need to use an SNP panel with a higher density than Illumina Ovine SNP50 BeadChip for genomic selection and ...
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Linkage Disequilibrium Estimation in Low Coverage High-Throughput Sequencing Data
... analysis. LD is often estimated using haplotypes phased from genotype data via various software packages and algorithms such as BEAGLE (Browning and Browning 2007), fastPHASE (Scheet and Stephens 2006), MaCH (Li ...
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Protective association of VDR gene polymorphisms and haplotypes with multiple sclerosis patients in Egyptian population
... and linkage disequilibrium (LD) in MS Egyptian ...and linkage disequilibrium analysis based on the five genetic loci was studied on the detected ...
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Integrating QTL analysis into plant breeding practice using Bayesian statistics
... of linkage disequilibrium (LD) or the non-independence between marker alleles and quantitative trait locus (QTL) alleles in the ...within-family LD is used and thus effect estimates will be ...
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Associative Transcriptomics Study Dissects the Genetic Architecture of Seed Glucosinolate Content in Brassica napus
... several linkage groups in ...of linkage disequilibrium (LD) in 85 winter rapeseed genotypes was found to be very low, with a mean r 2 of ...
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The ontology of genetic susceptibility factors (OGSF) and its application in modeling genetic susceptibility to vaccine adverse events
... e.g., linkage disequilibrium (LD, non-random association between two or more loci) haplotype, a linkage region, genetic polymorphisms, alleles and so ...
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Diplotyper: diplotype-based association analysis
... HL plays a key role in the interconversion between two HDL subspecies and the indirect pathway of hepatic cho- lesterol uptake in reverse cholesterol transport with invol- vement of HDL [13,14]. HDL-C levels are used ...
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439_2016_1738_MOESM1_ESM.pdf
... S2 Main effect filter analysis - underlying linkage disequilibrium (LD) structure of SNPs within pairwise interactions (P-value < 0.05) associated with total cholesterol level.!. S3 [r] ...
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Variant Set Enrichment: an R package to identify disease-associated functional genomic regions
... Study; LD: Linkage Disequilibrium; lncRNAs: Long-noncoding RNAs; LUAD: Lung adenocarcinoma; MRVS: Matched random variant sets; PRAD: Prostate adenomcarcinoma; SNP: Single nucleotide polymorphisms; ...
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Multi-locus approaches for the measurement of selection on correlated genetic loci
... term direct selection indirect selection total selection linkage disequilibrium LD selection coefficient s polygenic modeling PVE PGE n-γ PIP HPDI definition selection on a genetic locus[r] ...
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Genetic association of SNPs in the FTO gene and predisposition to obesity in Malaysian Malays
... and linkage disequilibrium (LD) blocks in various regions of the FTO gene are associated with predisposition to obesity in Malaysian ...testing, LD testing, and haplotype association analysis ...
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Genetic diversity and population structure of Plasmodium falciparum in the Philippines
... strong linkage disequilibrium (LD) when the single-clone haplotype (SCH) was used in the multilocus LD analysis, while in the high malaria transmission areas (Palawan and Davao del Norte), ...
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Association mapping to dissect and exploit existing natural variation for crop improvement
... between linkage analysis based mapping association mapping and linkage disequilibrium (LD) mapping, and then described the technique of association mapping used to dissect the genetic basis of ...
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