long non-coding RNA (lncRNA)
Original Article Long non-coding RNA ANRIL promotes tumorigenesis in glioma via MAPK signaling pathways
... is non-coding [3]. Among these, there is a kind of non-coding RNA called long non-coding RNA (lncRNA >200 bp in length), which have been proven to ...
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CRNDE: an oncogenic long non-coding RNA in cancers
... lncRNA: Long non- coding RNA; CRC : Colorectal cancer; HCC: Hepatocellular carcinoma; BC: Breast cancer; GC: Gastric cancer; RCC : Renal cell carcinoma; MAPK: Mitogen-acti- vated protein ...
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The Long Non-coding RNA Malat1 Regulates Inflammatory Cytokine Production in Chronic Diabetic Complications
... [59]. Non-coding RNAs (ncRNAs) were considered to be 'junk DNA' or ‘noise’ until recently when it was discovered that they not only make up the majority of the human genome, but many of them are highly ...
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Original Article Prognosis and clinicopathology of long non-coding RNA HOTTIP in tumors
... With advances of sequencing technologies, vital roles of long non-coding RNA (lncRNA) in the generation and development of tumors are being revealed. lncRNAs, which used to be con- sidered ...
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<p>Latest Advances of Long Non-Coding RNA SNHG5 in Human Cancers</p>
... lncRNA, long non-coding RNA; SNHG5, small nucleolar RNA host gene 5; ncRNA, non-coding RNA; miRNA, microRNA; siRNA, small interfering RNA; tRNA, transfer ...
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Original Article Function and mechanism of long non-coding RNA KIAA0495 in glioma
... of long non-coding RNA KIAA0495 in human glioma tissues, and the effect of U251 glioma cells on the biological function as well as its ...
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Enhanced expression of long non coding RNA NEAT1 is associated with the progression of gastric adenocarcinomas
... Methods: One hundred thirty-one GAC tissues and matched adjacent normal tissues (ANTs) were collected from patients who undergone surgery. Differences in of NEAT1 expression were examined via quantitative reverse ...
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Effects of long non-coding RNA Gm14461 on pain transmission in trigeminal neuralgia
... Background: This study aims to investigate the role of long non-coding RNA Gm14461 in regulating pain transmission in trigeminal neuralgia (TN). The mouse TN model was produced by chronic ...
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<p>Construction and Analysis of a Long Non-Coding RNA-Associated Competing Endogenous RNA Network Identified Potential Prognostic Biomarkers in Luminal Breast Cancer</p>
... LncRNA, a type of RNA with limited protein-coding ability, is previously viewed as transcriptional “ noise ” without biological functions. 14 Recently, lncRNAs are increasingly reported to be closely ...
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Cancer subtypes classification using long non-coding RNA
... LncRNAs have a crucial role in the activation of oncogenic signaling pathways that drive the cancer phenotype [28]. The oncoproteins MYC and p53, frequently deregulated in cancers, are under the influence of lncRNA ...
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ZFAS1: a novel tumor-related long non-coding RNA
... endogenous RNA (ceRNA) is a novel regula- tory mechanism whereby lncRNAs function as ceRNA to sponge microRNAs (miRNAs) and regulate their down- stream signaling pathways has been proposed and con- firmed ...
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Gene regulation by the act of long non-coding RNA transcription
... 3’end of PHO5 and overlaps its gene body and promoter is associated with rapid activation of PHO5 by enabling nu- cleosome eviction. Biochemical inhibition of RNAPII elong- ation as well as genetic disruption of lncRNA ...
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CCAT2 is an oncogenic long non-coding RNA in pancreatic ductal adenocarcinoma
... that long non-coding RNAs (lncRNAs) (> 200 nucleotides in length), one of the two widely-investigated classes of non-coding RNAs, plays essential roles in the development, ...
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Long non-coding RNA UCA1 is a predictive biomarker of cancer
... advanced non-small cell lung cancer (NSCLC) that harbor mutations that activate epidermal growth factor receptor (EGFR) can be treated with EGFR-tyrosine kinase inhibitors (TKIs) such as ...in non-resistant ...
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Long non-coding RNA ENST00000457645 reverses cisplatin resistance in CP70 ovarian cancer cells.
... Ovarian cancer is one of the most common gynecologic malignant tumors. Previous epidemiological studies have indicated that approximately 200,000 new cases are diagnosed every year worldwide, and the associated mortality ...
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Expression of long non-coding RNA DLX6-AS1 in lung adenocarcinoma
... RNA extraction and quantitative real-time fluorescent To further certify the generality of lncRNAs expression pattern, specimens from 72 patients were used to per- form qRT-PCR assay. Total RNA was ...
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Activation of an endogenous retrovirus-associated long non-coding RNA in human adenocarcinoma
... selected RNA-seq libraries generated in a previously described study ...ADenocarcinoma RNA) revealed significantly increased expression of this lncRNA in tumors ...in non-malignant tissue, we ...
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Original Article Long non-coding RNA expression profile in atrial fibrillation
... recently, long non-coding RNAs (lncRNAs), generally defined as non-coding RNAs of more than 200 nt in length without known protein- coding function [15], have risen to ...
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MALAT1: a druggable long non-coding RNA for targeted anti-cancer approaches
... hnRNPK RNA-binding proteins respectively, finally repressing CDKN1A and CDKN2B transcription ...[46–48]. RNA-Seq analysis of the prostate cancer transcriptome identified 121 unanno- tated ncRNA transcripts, ...
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Effect of long non-coding RNA AOC4P on gastrointestinal stromal tumor cells
... insight on the mechanism of AOC4P on GIST, we examined the cell proliferation, migration ability, invasive ability, and apoptosis activity, demonstrating that si AOC4P can inhibit cell proliferation, reduce migration and ...
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