Long non-coding RNA (lncRNAs)
Original Article Long non-coding RNA ANRIL promotes tumorigenesis in glioma via MAPK signaling pathways
... is non-coding [3]. Among these, there is a kind of non-coding RNA called long non-coding RNA (lncRNA >200 bp in length), which have been proven to ...
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The Long Non-coding RNA Malat1 Regulates Inflammatory Cytokine Production in Chronic Diabetic Complications
... [59]. Non-coding RNAs (ncRNAs) were considered to be 'junk DNA' or ‘noise’ until recently when it was discovered that they not only make up the majority of the human genome, but many of them are highly ...
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CRNDE: an oncogenic long non-coding RNA in cancers
... lncRNA: Long non- coding RNA; CRC : Colorectal cancer; HCC: Hepatocellular carcinoma; BC: Breast cancer; GC: Gastric cancer; RCC : Renal cell carcinoma; MAPK: Mitogen-acti- vated protein ...
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<p>Latest Advances of Long Non-Coding RNA SNHG5 in Human Cancers</p>
... lncRNA, long non-coding RNA; SNHG5, small nucleolar RNA host gene 5; ncRNA, non-coding RNA; miRNA, microRNA; siRNA, small interfering RNA; tRNA, transfer ...
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Expression and clinical significance of long non coding RNA HNF1A AS1 in human gastric cancer
... In this study, we determined that the expression level of HNF1A-AS1 in three gastric cancer cell lines was signifi- cantly decreased relative to that in normal gastric epithelial cells. More importantly, it was ...
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Clinical significance of long non-coding RNA HOTTIP in early-stage non-small-cell lung cancer
... between lncRNAs, mRNAs and miRNAs have been described [38], we ex- plored a possible association between the mRNAs and miRNAs whose expression correlated with HOTTIP ac- cording to TGCA data on adenocarcinoma ...
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<p>Construction and Analysis of a Long Non-Coding RNA-Associated Competing Endogenous RNA Network Identified Potential Prognostic Biomarkers in Luminal Breast Cancer</p>
... relationship. After screening, 240 pairs of lncRNA – miRNA and 115 pairs of mRNA – miRNA remained. Thus, a ceRNA topology network with 356 edges and 288 nodes, including 160 lncRNAs, 15 miRNAs, and 113 mRNAs was ...
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Enhanced expression of long non coding RNA NEAT1 is associated with the progression of gastric adenocarcinomas
... 10]. LncRNAs are perva- sively transcribed in the genome and are emerging as new players in tumorigenesis due to their various functions in transcriptional, posttranscriptional, and epigenetic mecha- nisms of gene ...
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Long non-coding RNA: a new player in cancer
... revealed lncRNAs, like miRNAs, function as important regulators in gene regulatory networks and exert crucial roles in cancer ...progression. LncRNAs have become new and important players and demonstrated ...
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Original Article Long non-coding RNA H19 promotes colorectal cancer metastasis via negative modulation of miR-148b
... and lncRNAs have been well characterized that they can regulate protein- coding ...and lncRNAs also can form a well-orchestrated regulatory interaction network: miRNAs and lncRNAs are able to ...
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Long non-coding RNA ENST00000457645 reverses cisplatin resistance in CP70 ovarian cancer cells.
... that lncRNAs play critical roles in the pathogenesis of multiple diseases (Archer et ...Although lncRNAs do not encode proteins, they do regulate a variety of genes that participate in cell signaling, ...
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Biological function in the twilight zone of sequence conservation
... then long non-coding RNAs (lncRNAs) are located at the other: most multi- exonic lncRNA loci exhibit little or no cross-vertebrate sequence conservation ...an RNA-mediated function, but ...
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Expressions of Long Non Coding RNAs in Carcinogenesis of Cervix: A Review
... of lncRNAs grouped according to their proximity to the closest protein- coding transcripts ...that LncRNAs are novel nonprotein-coding tran- scripts, which plays a key role in development and ...
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Transcriptomic signature associated with carcinogenesis and aggressiveness of papillary thyroid carcinoma
... of non-coding RNAs is indispensable for fine-tuning the genetic network, and its dysregulation is tightly associated with the pathogenesis of cancers ...of long noncoding RNAs (lncRNAs) in ...
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Abstract: Long non-coding RNAs (lncRNAs) are a novel class of regulatory RNA molecules and they
... Numerous lncRNAs are functionally correlated with ED and its associated diseases in recent studies, such as highly upregulated in liver cancer (HULC) [49,50], metastasis associated lung adenocarcinoma transcript 1 ...
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Global Human Health Risks for Arthropod Repellents or Insecticides and Alternative Control Strategies
... of long non-protein coding RNAs (lncRNAs) in primary human ...While lncRNAs are believed to play a critical role in numerous important biological processes many still remain ...
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The functional role of long non-coding RNAs and epigenetics
... versatile lncRNAs that have been evidenced, such as Kcnq1ot1, Airn, Xist and ...specific non-coding transcript antisense Igf2r RNA (Airn, 108 kb), is required for the silencing of three genes ...
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<p>Roles of Wnt/β-Catenin Signaling Pathway Regulatory Long Non-Coding RNAs in the Pathogenesis of Non-Small Cell Lung Cancer</p>
... cytoplasmic RNA 1 (BCYRN1) to induce NSCLC cell proliferation and invasion is primarily due to the elevated expression of cell cycle- related proteins CDK4 and some crucial components of the Wnt/ β -catenin ...
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<p>Association Between lncRNA HULC rs7763881 Polymorphism and Gastric Cancer Risk</p>
... antisense RNA; HULC, highly upregulated in liver cancer; HWE, Hardy Weinberg equilibrium; LncRNAs, long non-coding RNAs; LNM, lymph node metastasis; MALAT1, metastasis-associated lung ...
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Long non coding RNAs (lncRNAs) are dysregulated in Malignant Pleural Mesothelioma (MPM)
... that lncRNAs have important functional roles in cancer development. LncRNAs may therefore be useful diagnostic and prognostic biomarkers especially given their higher tissue ...the non-coding ...
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