Lung Diseases, Interstitial
Pulmonary hypertension in chronic interstitial lung diseases
... of interstitial lung diseases (ILDs), particularly in idiopathic pulmonary fibrosis and ILD associated with connective tissue ...other lung diseases, such as combined pulmonary fibrosis ...
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Comorbidities in interstitial lung diseases
... individual lung diseases is grouped within a single category in the world PH classification (group 3) ...idiopathic interstitial pneumonia (IIP), PH-IPF tends to be reported in published ...
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Long-term macrolides in diffuse interstitial lung diseases
... diffuse interstitial lung diseases (ILDs) and pulmonary ...“ interstitial lung disease ” , “ idiopathic pulmonary fibrosis ” , “ organising pneumonia ” and “ extrinsic allergic ...
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Role of imaging in progressive-fibrosing interstitial lung diseases
... ABSTRACT Imaging techniques are an essential component of the diagnostic process for interstitial lung diseases (ILDs). Chest radiography is frequently the initial indicator of an ILD, and comparison ...
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Endotoxin markers in bronchoalveolar lavage fluid of patients with interstitial lung diseases
... Environmental endotoxin when respired may trigger either the innate or adaptive immunity, depending on concentration and time of exposure [14]. The endotoxin in BALf could therefore reflect a role of air-borne LPS (e.g. ...
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Smoking and interstitial lung diseases
... desquamative interstitial pneumonia (DIP) and pulmonary Langerhans cell histiocytosis (PLCH), three chronic diffuse lung diseases that are strongly aetiologically linked to smoking ...(RA-ILD), ...
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Angiogenesis in Interstitial Lung Diseases: a pathogenetic hallmark or a bystander?
... 4. Pathogenetic pathways during aberrant angiogenesis Several transcription factors play instrumental role in pro- moting angiogenesis and sensing the environmental cues that drive this process. Strieter et al. [22] ...
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Lung Pattern Classification for Interstitial Lung Diseases Using an Artificial Neural Network
... ABSTRACT: Lung is the organ that allows us to breathe and lung disease are the disorders that affect the ...the lung diseases by effective feature extraction through Dual-Tree Complex Wavelet ...
6
Personalised medicine in interstitial lung diseases
... ABSTRACT Interstitial lung diseases in general, and idiopathic pulmonary fibrosis in particular, are complex disorders with multiple pathogenetic pathways, various disease behaviour profiles and ...
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Increased Levels of Hyaluronic Acid in Bronchoalveolar Lavage from Patients with Interstitial Lung Diseases, Relationship with Lung Function and Inflammatory Cells Recruitment
... Purpose: Interstitial Lung Diseases (ILD) are characterized by inflammation and fibrosis. It de- scribed the role of hyaluronic acid (HA) as an immune-regulator. It is not known if HA contri- butes ...
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Multidisciplinary evaluation of interstitial lung diseases: current insights
... fibrotic lung disease based on the 2011 ATS/ ERS/ALAT/JRS HRCT criteria for a UIP pattern was reported as moderate, with no significant improvement among thoracic radiologists with >25 years of experience ...
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Acute exacerbations of progressive-fibrosing interstitial lung diseases
... There are no randomised studies on which to base optimal management of AE in ILDs. In IPF, international management guidelines recommend the use of supportive care with symptom palliation and long-term oxygen therapy ...
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Surfactant gene polymorphisms and interstitial lung diseases
... Genetic analysis showed a mutation in one allele of the SP-C gene. The heterozygous substitution of A to G was located in the first base of intron 4, abolishing the normal donor splice site and resulting in the skipping ...
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Fibrosing interstitial lung diseases: knowns and unknowns
... HP is a complex syndrome caused by sensitisation to an inhaled antigen that leads to an aberrant immune response in the small airways and lung parenchyma. Susceptibility is believed to be affected by genetics, ...
9
Management of acute respiratory failure in interstitial lung diseases: overview and clinical insights
... ventilator-induced lung injury (VILI) [54, 85], and, subsequently, the high mortality rate of ILD patients in the ICU ...is lung transplant [89], and the decision to proceed to intensive life support ...
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An integrated approach in the diagnosis of smoking-related interstitial lung diseases
... upper lung predominance and sparing of the lung bases in a young heavy smoker man is characteristic of ...cystic lung disease, macrophagic alveolitis on BAL examination may support the diagnosis of ...
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Childhood Interstitial Lung Diseases: An 18-year Retrospective Analysis
... pursue lung biopsy (Supple- mental Fig ...undergone lung biopsy, with originally assigned patho- logic descriptions of chronic bronchiolitis, follicular bronchiolitis, normal paren- chyma with mild ...
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The natural history of progressive fibrosing interstitial lung diseases
... Data from clinical trials of investigational therapies made a large contribution to our understanding of the clinical course of IPF [104]. Ongoing large clinical trials con- ducted in patients with non-IPF fibrosing ILDs ...
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The genetics of interstitial lung diseases
... had only been described in the setting of DKC. These additional findings suggested that, at least in a small subset of patients, “telomeropathy”, or a syndrome in which multiple organs are affected by telomere ...
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The role of macrophages in interstitial lung diseases
... The accumulation of yellow-brown, haemosiderin-laden, pigmented macrophages ( “ smokers ’ macrophages ” ) within the lumens of respiratory bronchioles and into the peribronchiolar alveolar spaces (figure 1) is seen very ...
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