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Lung function decline

Lung function decline in COPD

Lung function decline in COPD

... that decline in the forced expiratory volume in the first second (FEV 1 ) in chronic obstructive pulmonary disease (COPD) is slow at the beginning, becoming faster with more advanced ...the lung ...

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Predicting Lung Function Decline with Serum Pneumoproteins: A Case Control Study

Predicting Lung Function Decline with Serum Pneumoproteins: A Case Control Study

... in lung function leading to death or lung trans- plant and would have not been captured in our ...predict lung disease in SSc is of great ...rapid lung function ...rapid ...

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Occupation and three-year incidence of respiratory symptoms and lung function decline: the ARIC Study

Occupation and three-year incidence of respiratory symptoms and lung function decline: the ARIC Study

... future lung function ...with lung function decline and lung function decline is associated with the inability to exhale for six seconds, than our analyses may not ...

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Contribution of alpha- and beta-defensins to lung function decline and infection in smokers: an association study

Contribution of alpha- and beta-defensins to lung function decline and infection in smokers: an association study

... to lung function decline in a large population of white individu- ...the lung; 2) we included only white subjects in the association study in order to mini- mize the potential effects of ...

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CC16 levels correlate with cigarette smoke exposure in bronchial epithelial cells and with lung function decline in smokers

CC16 levels correlate with cigarette smoke exposure in bronchial epithelial cells and with lung function decline in smokers

... and lung function parameter indicative of airflow obstruction; and the first in vitro demonstra- tion of the suppression of CC16 in normal bronchial epithelial cells after cigarette smoke ...worse ...

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Original Article Associations of interleukin-1 gene cluster polymorphisms with C-reactive protein concentration and lung function decline in smoking-induced chronic obstructive pulmonary disease

Original Article Associations of interleukin-1 gene cluster polymorphisms with C-reactive protein concentration and lung function decline in smoking-induced chronic obstructive pulmonary disease

... of lung function decline in smoking-induced ...292) decline of FEV1% predicted in the same ...of decline of lung function or CRP levels after adjusting for multiple ...

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Lung function decline in relation to diagnostic criteria for airflow obstruction in respiratory symptomatic subjects

Lung function decline in relation to diagnostic criteria for airflow obstruction in respiratory symptomatic subjects

... compared lung function decline between discordant and non-obstructed ...FEV1 decline, use of inhaled corticosteroids (regardless of the dose being pre- scribed) during each subsequent visit ...

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Relationship between exacerbation frequency and lung function decline in chronic obstructive pulmonary disease.

Relationship between exacerbation frequency and lung function decline in chronic obstructive pulmonary disease.

... concluded from their 10 year study that there was no relation between lung function decline and chest infections. However, their cohort had mild or no airflow obstruction, the diagnosis of ...

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Association of incidental emphysema with annual lung function decline and future development of airflow limitation

Association of incidental emphysema with annual lung function decline and future development of airflow limitation

... 1 decline was apparently higher in the emphysema group, but the difference was not statistically significant ( − ...FVC decline was significantly higher in the emphysema group ( − .../FVC decline ...

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Genetic variants affecting cross sectional lung function in adults show little or no effect on longitudinal lung function decline

Genetic variants affecting cross sectional lung function in adults show little or no effect on longitudinal lung function decline

... determine lung function decline may show heterogeneity across different groups is further supported by fi ndings from an earlier GWAS which identi fi ed suggestive evidence that different regions were ...

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The association of elevated circulating endocan levels with lung function decline in COPD patients

The association of elevated circulating endocan levels with lung function decline in COPD patients

... with lung func- tion parameters, Fas and Fas-L were analyzed by Pearson’s partial correlation test (adjusted for age, gender, body mass index and smoking history) and multiple linear ...

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Reducing lung function decline in patients with idiopathic pulmonary fibrosis: potential of nintedanib

Reducing lung function decline in patients with idiopathic pulmonary fibrosis: potential of nintedanib

... Although there is a paucity of pre-clinical data supporting the antifibrotic potential of nintedanib, an antifibrotic effect can be predicted from the compound’s capacity to inhibit PDGF, FGF, and VEGF. PDGF comprises a ...

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NK cell activating receptor ligand expression in lymphangioleiomyomatosis is associated with lung function decline

NK cell activating receptor ligand expression in lymphangioleiomyomatosis is associated with lung function decline

... NK function may also play a role in LAM pathogenesis, including reduced tumor surveillance and altered cytotoxicity of NK ...longitudinal lung function data in this ...cell function in LAM may ...

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Symptoms and lung function decline in a middle-aged cohort of males and females in Australia

Symptoms and lung function decline in a middle-aged cohort of males and females in Australia

... Age and baseline FEV 1 were associated with the decline in FEV 1 in both sexes (Table 3). However, maternal smoking and height were also independent predictors in males. Pack-years smoked and change in BMI were ...

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The need for a holistic approach for SSc-ILD – achievements and ambiguity in a devastating disease

The need for a holistic approach for SSc-ILD – achievements and ambiguity in a devastating disease

... FVC decline of patients with ...reduce lung function de- cline in patients with SSc-ILD and is now the first ap- proved drug for SSc-ILD in multiple countries ...on lung function de- ...

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Persistent Chlamydia Pneumoniae serology is related to decline in lung function in women but not in men. Effect of persistent Chlamydia pneumoniae infection on lung function

Persistent Chlamydia Pneumoniae serology is related to decline in lung function in women but not in men. Effect of persistent Chlamydia pneumoniae infection on lung function

... association between wheeze and C pn IgG was stronger in girls than in boys [4]. There are several reports on gender differences in the association between wheezing and asthma irrespective of C pn or other infections. The ...

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COPD Patients with Exertional Desaturation Are at a Higher Risk of Rapid Decline in Lung Function

COPD Patients with Exertional Desaturation Are at a Higher Risk of Rapid Decline in Lung Function

... rapid lung function decline Multivariate logistic regression analysis was conducted to in- dentify independent factors associated with rapid lung func- tion decline in patients with ...

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Characteristics and longitudinal progression of chronic obstructive pulmonary disease in GOLD B patients

Characteristics and longitudinal progression of chronic obstructive pulmonary disease in GOLD B patients

... In conclusion, we show that a subset of GOLD B pa- tients who moved to the higher risk D category after 1 year had greater symptoms and worse health status at the start of the study. Patient reported outcome scores ...

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A randomized controlled trial of vitamin E and selenium on rate of decline in lung function

A randomized controlled trial of vitamin E and selenium on rate of decline in lung function

... a function of the date the intervention was with- drawn, and was not driven by participant choice or par- ticipant ...on lung function decline to be ...

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A follow-up study of airway symptoms and lung function among residents and workers 5.5 years after an oil tank explosion

A follow-up study of airway symptoms and lung function among residents and workers 5.5 years after an oil tank explosion

... In conclusion, a follow-up study of respiratory health after an oil tank explosion showed persistent airways ef- fects after 5.5 years, in the group of residents and workers. Increased prevalence of lower airway symptoms ...

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