Macrolide-Resistance
Emergence of Macrolide Resistant Mycoplasma pneumoniae in Hong Kong Is Linked to Increasing Macrolide Resistance in Multilocus Variable Number Tandem Repeat Analysis Type 4 5 7 2
... During the 4-year period, types 4-5-7-2 and 3-5-6-2 were pre- dominant (Fig. 2). Together, the two types comprised 75% to 85% of all positive specimens in each year. The proportion of type 4-5-7-2 had an increasing trend ...
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Rapid Identification of Penicillin and Macrolide Resistance Genes and Simultaneous Quantification of Streptococcus pneumoniae in Purulent Sputum Samples by Use of a Novel Real Time Multiplex PCR Assay
... the standard curve. The data were analyzed by using Light- Cycler Software (v3.5) in the F2/F1 mode with a fit point calculation method. After amplification, 10 l of the PCR product was separated by electrophoresis on ...
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A Novel SimpleProbe PCR Assay for Detection of Mutations in the 23S rRNA Gene Associated with Macrolide Resistance in Mycoplasma genitalium in Clinical Samples
... carefully. Macrolide resistance is an increasing problem throughout the world (8, 9), and there is concern about the increased use of ...fluoroquinolone resistance (9, 29), and there is a need for ...
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Acquired macrolide resistance genes in nontypeable Haemophilus influenzae
... the macrolide resistance observed in Ci115 may be multifactorial and that all contributors to the resistance were not transferred to any ...to macrolide resistance are simply unable to ...
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Radiologic findings as a determinant and no effect of macrolide resistance on clinical course of Mycoplasma pneumoniae pneumonia
... of macrolide treatment for children with macrolide- resistant MP ...of macrolide resist- ...following macrolide treatment between the macrolide-susceptible and ...
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Treatment efficacy, treatment failures and selection of macrolide resistance in patients with high load of Mycoplasma genitalium during treatment of male urethritis with josamycin
... the macrolide resistance region of 23S rRNA were easily selected during ...for resistance due to wide usage of macrolides has been very large and selected for relatively high-levels of azithromycin ...
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Fluoroquinolone and Macrolide Resistance Associated Mutations in Mycoplasma genitalium
... the macrolide antibiotic azithromycin, but an increasing incidence of treatment failure over the last 5 years suggests the emergence of antibiotic ...for macrolide resistance have been found in the ...
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Genotypes and Related Factors Reflecting Macrolide Resistance in Pneumococcal Pneumonia Infections in Japan
... Although macrolide-resistant Streptococcus pneumoniae strains possessing either the ermB or mefA gene are very common in Japan, clinical and microbial factors in community-acquired pneumonia (CAP) caused by ...
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DETECTION OF MACROLIDE RESISTANCE GENES ERMB AND MEFA/E IN IRAQ
... to macrolide antibiotics such as clindamycin is mediated by two major mechanisms: methylation of ribosomal macrolide target sites, encoded by the gene erm(B), and drug efflux, encoded by the mef(A) gene ...
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Prospective Evaluation of ResistancePlus MG, a New Multiplex Quantitative PCR Assay for Detection of Mycoplasma genitalium and Macrolide Resistance
... Sample processing, amplification, sequencing, and detection. Urine and flocked swab (Copan Diagnostic, Brescia, Italy) samples were processed and specimens extracted as described previously (10). Detection of M. genitalium ...
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Mycoplasma genitalium Macrolide and Fluoroquinolone Resistance Detection and Clinical Implications in a Selected Cohort in New Zealand
... induce macrolide resistance in those who are ...macrolide resistance. Ideally, M. genitalium testing with resistance genotyping would be done at the time of ...genotypic ...
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Management of non gonococcal urethritis
... There are two regimens for azithromycin treatment, single one gram dose, or a five days course – 500 mg day one followed by 250 mg day 2–5. Single dose azithromy- cin is thought to induce macrolide ...
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Mycoplasma genitalium Prevalence, Coinfection, and Macrolide Antibiotic Resistance Frequency in a Multicenter Clinical Study Cohort in the United States
... infections, macrolide antibiotics are the cur- rent treatment of choice ...a macrolide antibiotic resistance genotype of ...genitalium macrolide resistance phenotype (51% in females and ...
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Antipneumococcal Activity of Telithromycin by Agar Dilution, Microdilution, E Test, and Disk Diffusion Methodologies
... both macrolide-susceptible and macrol- ide-resistant pneumococcal strains (6, 14, 21; ...for macrolide-resis- tant strains, all strains are susceptible at ...the macrolide resistance mechanism ...
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Prevalence of macrolide resistance and in vitro activities of six antimicrobial agents against clinical isolates of Streptococcus pneumoniae from a multi center surveillance in Malaysia
... other antibiotic shows a lower resistance rate with 33.8% for trimethoprim-sulfamethoxazole, 5.6% for cefotaxime and only 2.8% for penicillin. None of the isolates were resistant to amoxicillin-clavulanic acid and ...
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Dissemination of Macrolide Resistant Streptococcus pneumoniae Isolates Containing Both erm(B) and mef(A) in South Korea
... antimicrobial resistance are undoubtedly related to antibiotic pressure due to the wide- spread prescribing of ampicillin, erythromycin, and oral ceph- alosporins for upper respiratory infections and to the sale ...
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MACROLIDE –LINCOSAMIDE STREPTOGRAMIN B RESISTANCE IN ENTEROCOCCUS SPP ISOLATES IN BAGHDAD
... constitutive resistance to erythromycin (cMLSB) phenotype ,10 % for each ...inducible resistance to erythromycin with D-shape , 15% of ...is resistance to erythromycin and sensitive to clindamycin ...
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Therapeutic Failures of Antibiotics Used To Treat Macrolide Susceptible Streptococcus pyogenes Infections May Be Due to Biofilm Formation
... the macrolide resistance erm(A) subclass erm(TR) and erm(B) methylase genes formed less-thick biofilm than susceptible ...mef(A)-encoded macrolide efflux pump nor tetra- cycline resistance ...
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Management of Mycoplasma genitalium infections – can we hit a moving target?
... concurrent macrolide resistance mediating mutation leaving very few available treatment options [41, 59, 61, ...70]. Resistance to moxifloxacin and other fourth generation quinolones is mediated by ...
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Circulation of Distinct Treponema pallidum Strains in Individuals with Heterosexual Orientation and Men Who Have Sex with Men
... The genetic characteristics of T. pallidum subsp. pallidum have been of increasing interest over the past years for use as a tool to better understand the epidemiology of syphilis, as well as macrolide ...
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