Major histocompatibility complex class I genes
The Major Histocompatibility Complex Class I Genes of Zebrafish.
... the genes of the major histocompatibility complex (MHC) were named after the discovery that they encode the primary antigens responsible for determining transplant compatibility (Klein 2001), ...
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Evolutionary Relationships of Major Histocompatibility Complex Class I Genes in Simian Primates
... belzebuth) as representatives of subfamilies of Aotinae, Cebinae, cific manners and may function as classical class I in and Atelinae, respectively. We also used the rhesus monkey the absence of classical ...
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Rapid Evolution of Major Histocompatibility Complex Class I Genes in Primates Generates New Disease Alleles in Humans via Hitchhiking Diversity
... syntenic genes within our most recent common ancestor or, in more practical terms, sequence a larger number of haplotypes in all three ...MHC-I genes with respect to non-MHC genes ...
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Human cytomegalovirus US2 destabilizes major histocompatibility complex class I heavy chains.
... The dominant target of CTLs after infection of mice by murine CMV is the immediate-early protein pp89 (31, 43). A similar CTL response in humans directed against the analo- gous protein of HCMV, IE1, is not observed ...
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Macrophages Escape Inhibition of Major Histocompatibility Complex Class I-Dependent Antigen Presentation by Cytomegalovirus
... MHC I-subversive MCMV glycoproteins in macrophages. The genes m152 and m06 both encode type I transmembrane glycoproteins which interfere with the MHC class I pathway of antigen ...E ...
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Major histocompatibility complex class I antigens and the control of viral infections by natural killer cells.
... HLA-A genes showed that certain but not other class I molecules protected the C1R cells from NK cells, and exon-shuffling and point mutation studies indicated that a region near the pep- tide-binding ...
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Defective major histocompatibility complex class I expression on lymphoid cells in autoimmunity
... MHC class I ...MHC class II genes, which may in turn be linked to genes that affect MHC class I expression, we studied other autoimmune diseases to determine whether MHC ...
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Transcriptional and posttranscriptional regulation of class I major histocompatibility complex genes following transformation with human adenoviruses.
... Tumorigenicity of hamster and mouse cells transformed by adenovirus type 2 and 5 is not influenced by the level of class I major histocompatibility antigens expressed on the cells.. The [r] ...
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Gene conversion in the evolution of both the H-2 and Qa class I genes of the murine major histocompatibility complex.
... For each putative conversion event we have analyzed the sequences and gene regions in- volved, the apparent length of the event, and its effect on protein sequence [r] ...
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Cloned long-term cytolytic T-lymphocyte line with specificity for an immediate-early membrane antigen of murine cytomegalovirus.
... 57, 1986 class I glycoproteins encoded by genes of the K or DL loci of the murine major histocompatibility complex MHC 13, 27, simian virus 40-transformed cell lines 14 derived from the [r] ...
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Viral Proteins Interfering with Antigen Presentation Target the Major Histocompatibility Complex Class I Peptide-Loading Complex
... peptide-loading complex or may be unable to bind the peptide-loading complex due to VIPR action, resulting in ER exit in either ...peptide-loading complex, which consists of at least TAP, tapasin, ...
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Vesicular stomatitis virus infection of the central nervous system activates both innate and acquired immunity.
... the CNS. As early as 3 days p.i., expression of iNOS was detected in microglial cells in the OB. Increased level of iNOS expression coincided with decreased virus titers. In light of the inhibition of VSV production in ...
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MMP3 -1171 5A/6A Promoter Polymorphism Affects Level of Serum Major Histocompatibility Complex Class Chain Related B in Breast Cancer Patients
... 23]. So far, some mechanisms are reported for describing MICA/B expression and increased level of the proteins in the patients. Intracellular retention of MICA in human melanoma cell lines [24], short half-life of MICA/B ...
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Herpes Simplex Virus (HSV)-Mediated ICAM-1 Gene Transfer Abrogates Tumorigenicity and Induces Anti-Tumor Immunity
... Expression of the adhesion molecule ICAM- 1 and major histocompatibility complex class I antigens on human tumor cells is required for their inter- action with autologous lymphocytes in [r] ...
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Altered Expression of TAP-1 and Major Histocompatibility Complex Class I in Laryngeal Papillomatosis: Correlation of TAP-1 with Disease
... the major histocompatibility complex (MHC) class I protein expression in laryngeal papilloma tissue biopsies and cell culture of primary ...lating class I MHC cell surface ...
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Human Herpesvirus 7 U21 Tetramerizes To Associate with Class I Major Histocompatibility Complex Molecules
... to class I MHC molecules in immunoprecipitations of class I MHC molecules, regardless of whether immunoprecipitations were performed from metabolically labeled lysates of HHV-7-infected cells ...
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Murine cytomegalovirus interacts with major histocompatibility complex class I molecules to establish cellular infection.
... 4182-4189 0022-538X/93/074182-08$02.00/0 Copyright X 1993, American Society for Microbiology JOURNAL OF VIROLOGY, Murine Cytomegalovirus Interacts with Major Histocompatibility Complex C[r] ...
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Recovery from Friend disease in mice with reduced major histocompatibility complex class I expression.
... We investigated the effects of reduced H-2D& expression on recovery from Friend disease by using H-2b homozygous mice carrying a single P2-microglobulin gene disruption.. These mice had [r] ...
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The High-Frequency Major Histocompatibility Complex Class I Allele Mamu-B*17 Is Associated with Control of Simian Immunodeficiency Virus SIVmac239 Replication
... MHC class I alleles are linked to the control of pathogenic SIVmac239 replication, we measured postchal- lenge plasma virus concentrations in 181 Indian rhesus ma- caques from two independent ...
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PROTEIN MODELLING OF THE GENES OF ARTHRITIS: A REVIEW
... the major type of ligand but it is also observed to act as receptor for non-chemokine ligand like DEFB1 which in turn also affects calcium ion as well as cAMP ...
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