THE MAJOR HISTOCOMPATIBILITY COMPLEX AND DISEASE
Altered Expression of TAP-1 and Major Histocompatibility Complex Class I in Laryngeal Papillomatosis: Correlation of TAP-1 with Disease
... insidious disease caused by human papillomavirus (HPV) ...frequent disease recurrence, significant morbidity, and occasional ...recurrent disease and failure to suppress latent HPV ...the ...
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Major Histocompatibility Complex (MHC) Genes and Disease Resistance in Fish
... anti-virus disease resistance associated with the highly polymorphic classical MHC class I locus in rainbow trout, but could not find such differences (unpublished ...
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Characterization of the major histocompatibility complex locus association with Behçet’s disease in Iran
... Methods Study subjects The study participants were enrolled in the Behçet’s dis- ease outpatient clinic, Rheumatology Research Center, Shariati Hospital, at the Tehran University of Medical Sciences, Tehran, Iran from ...
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Recovery from Friend disease in mice with reduced major histocompatibility complex class I expression.
... We found no significant difference in H-2Db expression in comparisons of either cell type from H-2aIb heterozygous mice versus I32-m+' mice (Fig. 5), suggesting that a simple decrease in[r] ...
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Interspecies Major Histocompatibility Complex-Restricted Th Cell Epitope on Foot-and-Mouth Disease Virus Capsid Protein VP4
... CD25 upregulation on peptide-stimulated CD4 ⴙ CD8 ⴙ cells—dominated by Th memory cells in the pig—and inhibition using anti-major histocompatibility complex class II monoclonal antibodies indicated ...
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Murine AIDS is an antigen-driven disease: requirements for major histocompatibility complex class II expression and CD4+ T cells.
... did not develop MAIDS; however, MAIDS developed in class II-competent nulnu mice reconstituted with CD4+ T cells and in C2K/O mice reconstituted with B6 bone marrow to give class II-posi[r] ...
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The role of major histocompatibility complex molecules in luteal function
... 27. Weetman AP: Autoimmune thyroid disease: propagation and progression. Eur J Endocrinol 2003, 148:1-9. 28. Vives-Pi M, Vargas F, James RF, Trowsdale J, Costa M, Sospedra M, Somoza N, Obiols G, Tampe R, ...
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Development and Use of Multimeric Major Histocompatibility Complex Molecules
... All these studies show that a higher frequency of the presump- tive pathogenic cells accumulate at the site of pathology and strongly implicate these cells in the disease process. Multimeric MHC molecules can be ...
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Histocompatibility alloantigens in psoriasis and psoriatic arthritis Evidence for the influence of multiple genes in the major histocompatibility complex
... related disease populations, psoriasis and psoriatic ...two disease populations were ...two disease populations were HLA-Cw6, DRw7, and ...two disease groups that differed from the association ...
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Major Histocompatibility Complex Heterozygosity Reduces Fitness in Experimentally Infected Mice
... Although the current experimental evidence from congenic mice gives some support to the HA through allele-specific dominance, it is relevant to ask what the applicability of these results is to natural outbred pop- ...
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Extended major histocompatibility complex haplotypes in patients with gluten sensitive enteropathy
... studied major histocompatibility complex markers in randomly ascertained Caucasian patients with gluten-sensitive enteropathy and their ...this disease: HLA-B8, DR3, and ...
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The Major Histocompatibility Complex in Song Sparrows: Immunity, Signals, and Mate Choice
... affects disease resistance of song sparrows (Melospiza melodia) through additive (locally-good genes) and/or non-additive (heterozygote advantage) genetic effects; that the chemical composition of preen oil and ...
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Signatures of Demographic History and Natural Selection in the Human Major Histocompatibility Complex Loci
... Second, a model of symmetric overdominant selec- tion, affecting all heterozygous genotypes in all popula- tions in a similar manner, is only one of the selective regimes that can explain the high levels of heterozygos- ...
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MHC (MAJOR HISTOCOMPATIBILITY COMPLEX)
... three major classes: class I, class II and class ...MHC complex resides in the short arm of chromosome 6 and overall size of the MHC is approximately ...gene complex contains three loci A, B and C, ...
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Analysis and characterization of the swine major histocompatibility complex
... Characterization of a porcine genomic clone encoding a major histocompatibility antigen: Expression in mouse L cells. Breed and swine lymphocyte antigen haplotype[r] ...
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Serological definition of the bovine major histocompatibility complex
... animals subjected to repeat testing.. correctly defined; the absence of Mendelian inheritance would have suggested that antigens ma.y not have been correctly defined.[r] ...
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Female choice and variation in the major histocompatibility complex.
... Female choice can in fact reduce the observed proportions of homozygotes, maintain genetic polymorphism, influence mating-type frequencies and generate gametic disequ[r] ...
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Coevolution of the major histocompatibility complex and the t-complex in the mouse. II. Modification of response to sharing of histocompatibility antigens.
... For greater numbers of antigens associated with the +-haplotype than the t-haplotype (a > b), increased expression of incompatibility in +/t mothers promotes the pr[r] ...
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Polymorphism and balancing selection at major histocompatibility complex loci.
... Theory suggests that the number of alleles that differ at the sites targeted by selection (presumably the nonsynonymous sites in the PBR) should be equal to the [r] ...
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Genetics of survival in mice: subregions of the major histocompatibility complex.
... Alleles at the KAE, end were not significantly associated with survival for any model using long survival (although they were for short survival for males, both p[r] ...
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