Major histocompatibility complex gene
Major Histocompatibility Complex (MHC) Genes and Disease Resistance in Fish
... fish gene encoding a classical MHC class I molecule, identified by the peptide termini binding residues (reviewed in [35]) and in later studies by extensive allelic polymorphism, was by Grimholt et ...
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Replication Timing Analysis of the Major Histocompatibility Complex on Human Chromosome 6
... most gene dense class, with one every ...its gene content and, remarkably, it contains no ...this gene cluster constitutes a distinct subregion - the class IV region (Gruen & Weissman, ...
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Serological definition of the bovine major histocompatibility complex
... 'Ihe H-2 majo r histo conp atibi lity complex and the I inunune respo nse regio n: Gene tic vari ation , func tion, and orga niza tion.. and NIEDERHUBER, J.E.[r] ...
305
Extended major histocompatibility complex haplotypes in type I diabetes mellitus
... studied major histocompatibility complex markers in Caucasian patients with type I diabetes mellitus and their ...susceptibility gene for type I ...
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Extended major histocompatibility complex haplotypes in patients with gluten sensitive enteropathy
... heterozygotes for HLA-DR3 and DR7 was consistent with recessive inheritance of the major histocompatibility complex-linked susceptibility gene for gluten-sensitive enteropathy. On the other ...
7
The chromosomal order of genes controlling the major histocompatibility complex, properdin factor B, and deficiency of the second component of complement
... informative for C2 deficiency were found. Of 57 informative meioses, two crossovers were noted between the C2 deficiency gene and the HLA-B gene, with a recombinant fraction of 0.035. A lod score of 13 was ...
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Human Cytomegalovirus Disrupts the Major Histocompatibility Complex Class I Peptide-Loading Complex and Inhibits Tapasin Gene Transcription
... HCMV gene expression (13, 49), implying that the inhibition of tapasin through US3 is restricted to a few hours of HCMV ...a complex with TAP and US6 ...
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Conditional analysis of the major histocompatibility complex in rheumatoid arthritis
... Previous studies of MHC effects on RA susceptibility beyond the SE have identified additional independent signals but have been largely inconsistent, due at least in part to the difficulty of narrowing down regions of ...
5
Major Histocompatibility Complex Differentiation in Sacramento River Chinook Salmon
... 10.59 (fall and late fall). Previous allozyme studies for We characterized class II MHC variation in Sacra- nonsympatric populations of chinook in the Sacra- mento River chinook salmon and found significant fre- ...
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The Major Histocompatibility Complex Class I Genes of Zebrafish.
... I gene nomenclature follows the guidelines proposed for all species (Klein et ...“mhc1uaa” gene symbol is dissected as an example, the “mhc1” is included to define the sequence as class ...the gene, ...
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Major Histocompatibility Complex Variation in the Endangered Przewalski’s Horse
... The major histocompatibility complex (MHC) is a fundamental part of the vertebrate immune system, and the high variability in many MHC genes is thought to play an essential role in recognition of ...
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Gene conversion in the evolution of both the H-2 and Qa class I genes of the murine major histocompatibility complex.
... For each putative conversion event we have analyzed the sequences and gene regions in- volved, the apparent length of the event, and its effect on protein sequence [r] ...
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A defect in the regulation of major histocompatibility complex class II gene expression in human HLA DR negative lymphocytes from patients with combined immunodeficiency syndrome
... A defect in the regulation of major histocompatibility complex class II gene expression in human HLA-DR negative lymphocytes from patients with combined immunodeficiency syndrome.. Patie[r] ...
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Development and Use of Multimeric Major Histocompatibility Complex Molecules
... Recent studies have also highlighted the use of multimeric MHC in analysis of the maturation of immune responses. In- vestigators have shown, by using multimeric MHC, that with there is an avidity maturation of immune ...
5
Alloreactivity and Association of Human Natural Killer Cells with the Major Histocompatibility Complex
... hemopoietic histocompatibility system in mice has been shown to determine F1 hybrid resistance to a bone marrow graft from either parent with graft rejection mediated by radio- resistant NK cells ...poietic ...
7
Progress in spondylarthritis Progress in studies of the genetics of ankylosing spondylitis
... common complex genetic diseases such as ankylosing spondylitis (AS) rapidly in recent ...the major histocompatibility complex genetics of AS, and of KIR gene variants and the ...
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The Major Histocompatibility Complex in Song Sparrows: Immunity, Signals, and Mate Choice
... Locally-good gene effects at MHC may operate concurrently with and in opposition to non-additive genetic effects such as heterozygote advantage (Marr et ...
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Gene duplication and fragmentation in the zebra finch major histocompatibility complex
... The zebra finch genome, representing the taxonomi- cally diverse Passerine clade (approximately 5,400 spe- cies), offers the opportunity to characterize MHC structure in an avian lineage highly divergent from the ...
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Diminished expression of major histocompatibility complex facilitates the use of human induced pluripotent stem cells in monkey
... subunit may induce the degradation of α subunit or cause an inhibitory feedback response on the transcription of α subunit. Nevertheless, the remaining α subunits may be sufficient for NK inhibition. In addition, ...
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Down-regulation of major histocompatibility complex class I synthesis by murine cytomegalovirus early gene expression.
... The results indicate that MCMV infection down-regulates synthesis of both H-2Kb and H-2Db and slows considerably the rates of accumulation and maturation of these molecules within the in[r] ...
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