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Mature Bone

Structural requirements for parathyroid hormone action in mature bone  Effects on release of cyclic adenosine monophosphate and bone gamma carboxyglutamic acid containing protein from perfused rat hindquarters

Structural requirements for parathyroid hormone action in mature bone Effects on release of cyclic adenosine monophosphate and bone gamma carboxyglutamic acid containing protein from perfused rat hindquarters

... in mature bone, we perfused the surgically isolated hindquarters of adult male rats with either native bovine PTH-(1-84) [bPTH-(1-84)] or the synthetic amino-terminal fragment, bovine PTH-(1- 34) ...and ...

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Strenuous exercise induced remodelling of mature bone: relationships between in vivo strains and bone mechanics

Strenuous exercise induced remodelling of mature bone: relationships between in vivo strains and bone mechanics

... axial and shear strains microstrain for medial, anterior and lateral tarsometatarsus surfaces during slow walking trials 37cms~' for basal, age-matched control and exercise groups N=3 pe[r] ...

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Comparison of immature and mature bone marrow derived dendritic cells by atomic force microscopy

Comparison of immature and mature bone marrow derived dendritic cells by atomic force microscopy

... Bone marrow-derived dendritic cells were generated according to Lutz ’ s publication [10] with a little modifica- tion. In brief, cervical cords in female Balb/c mice with 6 to 8 weeks old (Sun Yat-sen University, ...

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Early life vitamin D depletion alters the postnatal response to skeletal loading in growing and mature bone

Early life vitamin D depletion alters the postnatal response to skeletal loading in growing and mature bone

... the bone and compare it with the different in vivo groups used in this ...the bone stiffness. If a higher volume of bone is undergoing high strain compared to other groups then this means that the ...

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Allopurinol and oxypurinol promote osteoblast differentiation and increase bone formation

Allopurinol and oxypurinol promote osteoblast differentiation and increase bone formation

... on bone formation, cell number and viability, gene expression and enzyme activity in differentiating and mature, bone-forming ...with mature osteoblasts displaying reduced levels of uric acid ...

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Mature osteoblasts dedifferentiate in response to traumatic bone injury in the zebrafish fin and skull

Mature osteoblasts dedifferentiate in response to traumatic bone injury in the zebrafish fin and skull

... calcifying bone matrix ...to mature bone tissue ...old bone was still distinguishable from the surrounding new bone matrix and still contained a crack ...lepidotrichia bone are ...

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Case Report Primary orbital dedifferentiated liposarcoma with leiomyosarcomatous and low-grade osteosarcomatous differentiation

Case Report Primary orbital dedifferentiated liposarcoma with leiomyosarcomatous and low-grade osteosarcomatous differentiation

... metaplastic bone because of under- recognization of both well-differentiated lipo- sarcoma and neoplastic ossified ...relatively mature bone component, suggestive of its malignant natures and an ...

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Fractures and Biomechanical Characteristics of the Bone

Fractures and Biomechanical Characteristics of the Bone

... of bone tissue is its ability to self-regeneration and therefore cannot be treated as a rigid material but rather as a dynamic system, which is constantly changing its structure [4] ...The bone has the ...

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Biocompatibility and in vivo osteogenic capability of novel bone tissue engineering scaffold A-W-MGC/CS

Biocompatibility and in vivo osteogenic capability of novel bone tissue engineering scaffold A-W-MGC/CS

... tissue-engineered bone had been degraded into a mesh- shaped structure with the generation of a large number of chondrocytes in the bone defect area containing a small amount of bone ...of ...

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Mineralisation of collagen rich soft tissues and osteocyte lacunae in Enpp1-/- mice

Mineralisation of collagen rich soft tissues and osteocyte lacunae in Enpp1-/- mice

... Sclerostin, which is secreted by osteocytes, inhibits Wnt signalling and negatively regulates bone formation [49]. We found that serum sclerostin levels were higher in Enpp1 −/− mice and that sclerostin mRNA ...

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Effects of salubrinal on development of osteoclasts and osteoblasts from bone marrow derived cells

Effects of salubrinal on development of osteoclasts and osteoblasts from bone marrow derived cells

... For Western blot analysis, RAW264.7 mouse monocyte/ macrophage cells (ATCC, Manassas, VA, USA) were grown in α−MEM containing 10% fetal bovine serum and antibi- otics (50 units/ml penicillin, and 50 μg/ml streptomycin; ...

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B cell survival, surface BCR and BAFFR expression, CD74 metabolism, and CD8⁻ dendritic cells require the intramembrane endopeptidase SPPL2A

B cell survival, surface BCR and BAFFR expression, CD74 metabolism, and CD8⁻ dendritic cells require the intramembrane endopeptidase SPPL2A

... In mature B cells, MHC II and full- length CD74 are primarily on the cell surface until the BCR is engaged by ...of mature B cells and DC subsets on functional SPPL2A and the existence of pharmacological ...

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PubMedCentral-PMC4899267.pdf

PubMedCentral-PMC4899267.pdf

... increasing bone mass, the impact of BMP signaling on bone quality and biomechanical properties under physiological conditions has not been fully elucidated, due to the lack of appropriate genetic animal ...

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Checkpoints that control B cell development

Checkpoints that control B cell development

... 24–28). This secures continuous, life-long generation of new MPPs, CLPs, and common myeloid progenitors (CMP), and hence also B lymphocytes (21). Since only a fraction of the pool of LT-pHSCs is mobilized to participate ...

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Influence of Ovariectomy on Bone Turnover and Trabecular Bone Mass in Mature Cynomolgus Monkeys

Influence of Ovariectomy on Bone Turnover and Trabecular Bone Mass in Mature Cynomolgus Monkeys

... on bone turnover and trabecular bone mass at the 3 clinically important skeletal sites in mature cynomolgus ...Lumbar bone mineral density (BMD) in vivo and serum and urinary bone ...

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Coexistent hairy cell leukaemia and hepatosplenic t-cell lymphoma: a case report

Coexistent hairy cell leukaemia and hepatosplenic t-cell lymphoma: a case report

... and bone marrow trephine biopsy were also ...negative. Bone marrow biopsy (Figures 3,4,5 and 6) revealed hypercellular bone mar- row with reduced orthotopic haematopoiesis and intrasinu- soidal ...

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Making Meaningful Things Together: Working Towards a Mature Business

Making Meaningful Things Together: Working Towards a Mature Business

... It is important for everyone on the team, independent of their discipline, to have a clear idea of what the core features and value proposition of a product or service is: what is the [r] ...

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B cell antigen receptor isotypes : implications for immune memory

B cell antigen receptor isotypes : implications for immune memory

... immature bone marrow B cells or mature lymph node B cells demonstrate that phenotypic variation or selection in the peripheral splenic marginal zone and follicular subsets of donor mice is not necessary for ...

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The P2Y(13) receptor regulates phosphate metabolism and FGF-23 secretion with effects on skeletal development

The P2Y(13) receptor regulates phosphate metabolism and FGF-23 secretion with effects on skeletal development

... the bone volume fraction (BV/TV), bone volume (BV), tissue volume (TV), and bone mineral density ...long bone CT analysis, right tibiae were dissected free of soft tissue, fixed in 70% ...

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Evidence for a stepwise program of extrathymic T cell development within the human tonsil

Evidence for a stepwise program of extrathymic T cell development within the human tonsil

... The development of a broad repertoire of T cells, which is essential for effective immune function, occurs in the thymus. Although some data suggest that T cell development can occur extrathymically, many researchers ...

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