Mesenchymal Stem Cells – MSC
Different populations and sources of human mesenchymal stem cells (MSC): A comparison of adult and neonatal tissue-derived MSC
... together, MSC-mediated immunosuppression is a multifaceted phenomenon based on several mechan- ...isms. MSC differentially regulate immune responses by inhibiting the differentiation of dendritic ...
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Transplantation of induced pluripotent stem cell-derived mesenchymal stem cells improved erectile dysfunction induced by cavernous nerve injury
... Mesenchymal stem cells (MSC) are special cells with multi-lineage differentiation abilities ...for MSC obtaining which covers umbilical cord blood, adipose tissue, and bone ...
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A novel and generalizable organotypic slice platform to evaluate stem cell potential for targeting pediatric brain tumors
... neoplastic cells persist and inevitably give rise to recurrent ...needed. Stem cells may provide the basis for a new approach. Emerging stem cell therapy of brain tumors The lack of efficacy ...
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Characterization and Therapeutic Application of Mesenchymal Stem Cells with Neuromesodermal Origin from Human Pluripotent Stem Cells
... Mesenchymal stem cells (MSC) hold great therapeutic potential for cell-based tissue engineering and regenerative medicine, as they offer the benefits of easy isolation, multipotency, paracrine ...
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Bovine fetal mesenchymal stem cells exert antiproliferative effect against mastitis causing pathogen Staphylococcus aureus
... combat. Mesenchymal stem cells (MSC) are multipotent progenitor cells equipped with a variety of factors that inhibit bacterial ...from MSC derived from fetal bovine bone marrow ...
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Transendothelial migration of human umbilical mesenchymal stem cells across uterine endothelial monolayers: junctional dynamics and putative mechanisms
... Abbreviations: Mesenchymal stem cells MSC from Wharton’s jelly of human umbilical cords WJ-MSC, human uterine microvascular endothelial cells HUtMEC, vascular endothelial cadherin VE-cad[r] ...
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Small extracellular vesicles secreted by human iPSC-derived MSC enhance angiogenesis through inhibiting STAT3-dependent autophagy in ischemic stroke
... especially stem cells including embryonic stem cells (ESC), neural stem/precursor cells (NSC/NPC), mesenchymal stem cells (MSC), and induced ...
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Evaluation of mesenchymal cells (MSC) and dapsone
... laeta venom inoculation, groups were treated with either PBS (C+), mesenchymal stem cells (MSC), 102.. dapsone (DAP), or in association of both MSC and DAP (MSC+DAP).[r] ...
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Mesenchymal stem cells exert anti-proliferative effect on lipopolysaccharide-stimulated BV2 microglia by reducing tumour necrosis factor-α levels
... 3 MSC were seeded in triplicate and allowed to adhere ...day, MSC were treated with 10 μg/ml mitomycin-C (Sigma) for 2 hours to halt their ...BV2 cells were then seeded at 5 × 10 3 ...harvesting. ...
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Mesenchymal stem cells: potential application for the treatment of hepatic cirrhosis
... Perry et al. [38] used degenerate electrical waveforms for patients with skin scars and showed that electrical stimulation significantly reduced scar scores and may guide cell migration. Furthermore, the physiological ...
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Human bone marrow mesenchymal stem cell-derived exosomes stimulate cutaneous wound healing mediates through TGF-β/Smad signaling pathway
... of MSC therapy or combined therapies with some unique bio- technology factors can stimulate cutaneous wound healing ...adipose-derived mesenchymal stem cells (AD-MSCs) platelet-rich plasma ...
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Dental follicle mesenchymal stem cell administration ameliorates muscle weakness in MuSK-immunized mice
... of cells to be administered per injection was de- termined during optimization ...bone MSC and DFMSC treatments were also compared (Additional file 1: Table ...
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Is Adipocyte Differentiation the Default Lineage for Mesenchymal Stem/Progenitor Cells after Loss of Mechanical Loading? A Perspective from Space Flight and Model Systems
... on cells of the microcirculation are well ...that cells such as mast cells often co-localize with nerves and are capable of amplifying neural signals (reviewed in ...resident cells may be a ...
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Iberian pig mesenchymal stem/stromal cells from dermal skin, abdominal and subcutaneous adipose tissues, and peripheral blood: in vitro characterization and migratory properties in inflammation
... the MSC population should ex- press specific markers such as CD105, CD73 and CD90, and be negative for CD45, CD34, CD14 or CD11b, CD79α or CD19 and HLA class II; and they should be able to differentiate to ...
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Mesenchymal stem cells in arthritic diseases
... T cells stimulate monocytes, macrophages, and FLSs to produce inflammatory mediators, including IL-1, TNF- α , IFN- γ , and IL-6, and secrete MMPs, leading to the systemic inflammation that eventually results in ...
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The superiority of conditioned medium derived from rapidly expanded mesenchymal stem cells for neural repair
... progenitor cells from the mesoderm and are also accessible from the bone marrow, adipose tissue, and placenta for culture ...lineage cells in appropriate experimental conditions [19, 20] and modulate the ...
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Exosomes Secreted from Human-Induced Pluripotent Stem Cell-Derived Mesenchymal Stem Cells Prevent Osteonecrosis of the Femoral Head by Promoting Angiogenesis
... pluripotent stem cell-derived mesenchymal stem cells (hiPS-MSC-Exos) could promote angiogenesis of ischemic tissue in limb ischemia and skin defects [17, ...and stem cells ...
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Safety of repeated transplantations of neurotrophic factors-secreting human mesenchymal stromal stem cells
... the MSC-NTF cells after intrastriatal transplantation in ...pre-labeled cells migrated and ...the cells were attracted Table 6 Histopathological findings in male and female C57BL/6 J mice ...
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Effect of bone marrow-derived mesenchymal stem cells and stem cell supernatant on equine corneal wound healing in vitro
... T cells and promotion of T-cell proliferation [35], and it has been shown that MHC class II proteins are upregulated by in- flammatory mediators including interferon (IFN)-γ ...
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Genetic modification of human mesenchymal stem cells helps to reduce adiposity and improve glucose tolerance in an obese diabetic mouse model
... Results: HG increased reactive superoxide (ROS) accumulation noted by day 7 both in cytosol and mitochondria. The OCR between the NG and HG exposed groups however did not change until 10 days at which point OCR of HG ...
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