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metabolomic profile

Changes in urinary metabolomic profile during relapsing renal vasculitis

Changes in urinary metabolomic profile during relapsing renal vasculitis

... urinary metabolomic profile at various time points during the disease course and found that the marked separation between MPO and HSA immunised animals at day 56 had largely disappeared by day 181 ...

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Serum metabolomic profile as a means to distinguish stage of colorectal cancer

Serum metabolomic profile as a means to distinguish stage of colorectal cancer

... controls; metabolomic profiles were determined by GC-MS and liquid chromatography-mass spectrometry ...The metabolomic profiles in CRC patients (including eight patients with stage IV CRC) were distinct ...

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Differential effects of dietary supplements on metabolomic profile of smokers versus non-smokers

Differential effects of dietary supplements on metabolomic profile of smokers versus non-smokers

... Changes in the metabolomic profile and clinical changes observed are associations and not necessarily causative. It has been reported that increases in free fatty acids induce oxidative stress by generating ...

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Selective Intrauterine Growth Restriction in Monochorionic Twin Pregnancies: Markers of Endothelial Damage and Metabolomic Profile

Selective Intrauterine Growth Restriction in Monochorionic Twin Pregnancies: Markers of Endothelial Damage and Metabolomic Profile

... serum metabolomic profile in selective intrauterine growth-restricted (sIUGR) monochorionic diamniotic (MCDA) twin fetuses presenting Doppler velocimetry ...non-targeted metabolomic profiling ...

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1HNMR-based metabolomic profile of rats with experimental acute pancreatitis

1HNMR-based metabolomic profile of rats with experimental acute pancreatitis

... characteristic metabolomic profile dif- fered in AP and SO ...1HNMR-based metabolomic approach was cap- able of distinguishing between plasma samples of AP rats and SO controls, providing a new and ...

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Effect of melittin on metabolomic profile and cytokine production in PMA-differentiated THP-1 cells

Effect of melittin on metabolomic profile and cytokine production in PMA-differentiated THP-1 cells

... metabolic profile of a tumour shows an increase in glycolysis under normoxic conditions, so that metabolism is shifted to produce lactic acid from pyruvate instead of the acetyl-CoA needed to feed the ...

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Metabolomic profile of glycolysis and the pentose phosphate pathway identifies the central role of glucose-6-phosphate dehydrogenase in clear cell-renal cell carcinoma

Metabolomic profile of glycolysis and the pentose phosphate pathway identifies the central role of glucose-6-phosphate dehydrogenase in clear cell-renal cell carcinoma

... metabolic profile of glycolysis and the pentose phosphate pathway (PPP) in human clear cell-renal cell carcinoma (ccRCC) and evaluate the role of these pathways in sustaining cell proliferation, maintenance of ...

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Exploring the Inflammatory Metabolomic Profile to Predict Response to TNF-alpha Inhibitors in Rheumatoid Arthritis

Exploring the Inflammatory Metabolomic Profile to Predict Response to TNF-alpha Inhibitors in Rheumatoid Arthritis

... employing metabolomic profiling to predict patients’ response to biological ...metabolic profile and the magnitude of the one-year change in the disease ...

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Metabolomic profile of amniotic fluid to evaluate lung maturity: the diaphragmatic hernia lamb model

Metabolomic profile of amniotic fluid to evaluate lung maturity: the diaphragmatic hernia lamb model

... The profile of these metabolites in- creases constantly during gestational ...choline profile have already been correlated with the fetal lung maturity ...the profile of these metabolites may be ...

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Initial Analysis of Lipid Metabolomic Profile Reveals Differential Expression Features in Myeloid Malignancies

Initial Analysis of Lipid Metabolomic Profile Reveals Differential Expression Features in Myeloid Malignancies

... Methods: Untargeted Shotgun MS/MS Analysis was performed to evaluate plasma samples from 153 participants, being 90 of the Control Group, 43 Myeloproliferative Neoplasms MPN, 11 Myelodys[r] ...

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Plasma metabolomic profile varies with glucocorticoid dose in patients with congenital adrenal hyperplasia

Plasma metabolomic profile varies with glucocorticoid dose in patients with congenital adrenal hyperplasia

... metabolome profile showed substantial overlap between groups 1&2 and groups 3&4 ...lomic profile was found between patients receiving 1–5 mg prednisolone equivalents daily (low GC, 64 patients) ...

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Deletion of TSPO resulted in change of metabolomic profile in retinal pigment epithelial cells

Deletion of TSPO resulted in change of metabolomic profile in retinal pigment epithelial cells

... Amino metabolism was disturbed by oxLDL treatment indecreased, both wildtype TSPO and Figure 5 and Table S1.acid Among 27 metabolites detected, 5 metabolites 16 and increased knockout ce[r] ...

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Biomarker discovery in neurological diseases: a metabolomic approach

Biomarker discovery in neurological diseases: a metabolomic approach

... interesting work defining metabolomic signatures in Parkinson’s disease (PD). They included 25 controls and 66 PD patients and used liquid chromatography followed by electrochemical detection (LCECA) to create a ...

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Metabolic profiling of hypoxic cells revealed a catabolic signature required for cell survival

Metabolic profiling of hypoxic cells revealed a catabolic signature required for cell survival

... Oxygen limitation, mitochondrial dysfunction, and the genetic reprogramming initiated under hypoxia are likely to elicit global metabolic changes beyond anaerobic glycolysis. To better under- stand the metabolic ...

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Plasma metabolomic profiling of proliferative diabetic retinopathy

Plasma metabolomic profiling of proliferative diabetic retinopathy

... the metabolomic profile of vitreous samples, and pathway enrichment analysis re- vealed that arginine metabolism was the pathway perturbed in the DR ...

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Metabolomic and BH3 profiling of esophageal cancers: novel assessment methods for precision therapy

Metabolomic and BH3 profiling of esophageal cancers: novel assessment methods for precision therapy

... elucidate metabolomic signatures that may be associated with ...a metabolomic signature will correlate with tumor death after nCRT for esophageal ...

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Metabolomics for predicting hyperglycemia in pregnancy: a protocol for a systematic review and potential meta-analysis

Metabolomics for predicting hyperglycemia in pregnancy: a protocol for a systematic review and potential meta-analysis

... Metabolomic studies in GDM have addressed bio- markers for early risk stratification, therapeutic effects of insulin and dietary treatment, and the risk of transition from GDM to short- or long-term T2DM. Several ...

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The application of metabolomic profiling to the effects of physical activity

The application of metabolomic profiling to the effects of physical activity

... observed that fatty acid release into plasma decreased with increasing exercise intensity [83] and fatty acid levels in plasma increased greatly during the minutes following a high-inten[r] ...

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1 Metabolomic study of polyamines in rat urine

1 Metabolomic study of polyamines in rat urine

... in multivariate analysis, but it maintained a similar level in GHB single and multiple administration 205. groups[r] ...

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High quality metabolomic data for Chlamydomonas reinhardtii

High quality metabolomic data for Chlamydomonas reinhardtii

... 218 peaks remained for the leakage comparison (table 1) of which the far majority of them (197 and 199, resp.) were found leaking at levels of less than 10% for both quenching methods. O[r] ...

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