MHC, major histocompatibility
ADP Ribosylation Factor 1 Activity Is Required To Recruit AP-1 to the Major Histocompatibility Complex Class I (MHC-I) Cytoplasmic Tail and Disrupt MHC-I Trafficking in HIV-1-Infected Primary T Cells
... cell, major histocompatibility complex class I (MHC-I) molecules present peptides derived from viral ...by MHC-I, the CTL releases perforins and gran- zymes that kill the virally infected ...
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Resistance of Major Histocompatibility Complex Class B (MHC-B) to Nef-Mediated Downregulation Relative to that of MHC-A Is Conserved among Primate Lentiviruses and Influences Antiviral T Cell Responses in HIV-1-Infected Individuals
... downregulate major histocompatibility complex class A (MHC-A) and MHC-B from the cell ...absolute MHC-A and MHC-B downregulation abilities, all lentiviral Nef lineages ...
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Major Histocompatibility Complex (MHC) Genes and Disease Resistance in Fish
... nonclassical MHC class I molecules, only UGA may bind peptides in a manner very reminiscent of classical MHC class I [67], but in rainbow trout the UGA 5’-UTR has additional AUGs plus an inverted repeat ...
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Antibiotic therapy and outcome from immune-checkpoint inhibitors
... Lipopolysaccharide; MHC: Major Histocompatibility Complex; NOD1: Nucleotide-binding oligomerization domain-containing protein 1; NSCLC: Non-small Cell Lung Cancer; ORR: Overall response rate; OS: ...
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Characterization of a Murine Cytomegalovirus Class I Major Histocompatibility Complex (MHC) Homolog: Comparison to MHC Molecules and to the Human Cytomegalovirus MHC Homolog
... with m144. SDS-PAGE analysis of immunoprecipitated pro- tein from cells expressing m144 and mb2m also reveals two bands migrating at 45 and 12 kDa (data not shown). m144- mb2m was purified from transfected cell ...
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Altered Expression of TAP-1 and Major Histocompatibility Complex Class I in Laryngeal Papillomatosis: Correlation of TAP-1 with Disease
... and MHC-I are co-down-regulated in laryngeal pap- illoma ...reduced MHC-I. Figure 1 depicts the contrast in expression of TAP-1 and MHC-I between cryopreserved normal and papilloma tis- ...and ...
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Clinical, immunological and genetic features in eleven Algerian patients with major histocompatibility complex class II expression deficiency
... four MHC II regula- tory genes, thus defining four complementation groups: MHC2A for group A, RFXANK for group B, RFX5 for group C and RFXAP for group D ...of MHC class II deficiency ...
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Allorecognition by T Lymphocytes and Allograft Rejection
... allogeneic major histocompatibility complex (MHC) molecules on donor cells (direct pathway) and/or donor peptides presented by self-MHC molecules on recipient antigen-presenting cells (APCs) ...
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TARGETING TOOLS FOR A DNA VACCINE CARRIER, A DESIGN IN PREVENTION OF CANCER
... HLA. Major histocompatibility complex-Ι (MHC Ι) is a fundamental protein usually found on the plasma ...virus. MHC Ι is composed of two chains: a light chain (β- macroglobulin; β2m) and a ...
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Genomic analysis of stress, aggression and boldness in rainbow trout
... and major challenge in evolutionary biology is to understand the associations between genotype and phenotypes, with a recent emphasis on determining the role of genes upon apparently complex ...Parus major ...
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Diminished expression of major histocompatibility complex facilitates the use of human induced pluripotent stem cells in monkey
... The future of stem cell therapy is mainly dependent on overcoming the side-effects, rather than finding their new therapeutic potentials. We had previously hypothe- sized that if iPSCs were disseminated in disease ...
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Vesicular stomatitis virus infection of the central nervous system activates both innate and acquired immunity.
... of major histocompatibility complex (MHC) class I molecules on astrocytes and microglial, endothelial, and ependymal cells was also rapidly induced and followed by induced expression of MHC ...
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Dynamics of major histocompatibility complex class II-positive cells in the postischemic brain - influence of levodopa treatment
... callosum; MHC II: major histocompatibility complex class II; tMCAO: transient Middle cerebral artery occlusion; FACS: fluorescence-activated cell sorting; HBSS: Hank ’ s balanced salt solution; EDTA: ...
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Gains and Losses of HLA Class II (DR) and CD4 in Atypical Hyperplasia, Carcinoma in situ and Infiltrating Ductal Carcinoma of the Breast
... of major histocompatibility complex (MHC) class II (HLA-DR) on atypical and malignant primary mammary epithelial cells, as well as the magnitude of the stromal T lymphocytes (T4 subset) at the tumor ...
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Fine structure of a virus-encoded helper T-cell epitope expressed on FBL-3 tumor cells.
... To understand peptide-major histocompatibility complex MHC interactions and the subsequent recognition of peptides by specific T cells, we used peptides of decreasing lengths to determin[r] ...
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FDA-approved immunosuppressants targeting staphylococcal superantigens: mechanisms and insights
... the major histocompatibility complex class II (MHC II) molecules and specific Vβ regions of T-cell receptors (TCRs), resulting in the stimulation of both monocytes/macrophages and T ...with ...
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The chromosomal order of genes controlling the major histocompatibility complex, properdin factor B, and deficiency of the second component of complement
... INTRODUCTION Evidence has been presented for the linkage of the HLA histocompatibility genes HLA-A, B, C, D,1 collectively referred to as the major histocompatibility complex MHC, to the[r] ...
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The Major Histocompatibility Complex Class I Genes of Zebrafish.
... the major histocompatibility complex (MHC) were named after the discovery that they encode the primary antigens responsible for determining transplant compatibility (Klein 2001), MHC molecules ...
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A Novel Bat Herpesvirus Encodes Homologues of Major Histocompatibility Complex Classes I and II, C-Type Lectin, and a Unique Family of Immune-Related Genes
... encode major histocompatibility complex (MHC)-related proteins, 2 to encode MHC class I homologues, and 3 to encode MHC class II homologues; 4 encode the homologues of C-type lectin- or ...
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Kaposi's Sarcoma-Associated Herpesvirus Viral Interferon Regulatory Factor 3 Inhibits Gamma Interferon and Major Histocompatibility Complex Class II Expression
... of MHC II in PEL cells compared to KSHV-negative B cell ...of MHC II transcripts upon vIRF-3 ...of MHC II (HLA-DRA/B, -DPA/B, and -DQA/B) mRNA was analyzed by semiquantitative RT-PCR (HLA-DRA/B and ...
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