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MHC, major histocompatibility complex

Resistance of Major Histocompatibility Complex Class B (MHC-B) to Nef-Mediated Downregulation Relative to that of MHC-A Is Conserved among Primate Lentiviruses and Influences Antiviral T Cell Responses in HIV-1-Infected Individuals

Resistance of Major Histocompatibility Complex Class B (MHC-B) to Nef-Mediated Downregulation Relative to that of MHC-A Is Conserved among Primate Lentiviruses and Influences Antiviral T Cell Responses in HIV-1-Infected Individuals

... downregulate major histocompatibility complex class A (MHC-A) and MHC-B from the cell ...absolute MHC-A and MHC-B downregulation abilities, all lentiviral Nef lineages ...

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ADP Ribosylation Factor 1 Activity Is Required To Recruit AP-1 to the Major Histocompatibility Complex Class I (MHC-I) Cytoplasmic Tail and Disrupt MHC-I Trafficking in HIV-1-Infected Primary T Cells

ADP Ribosylation Factor 1 Activity Is Required To Recruit AP-1 to the Major Histocompatibility Complex Class I (MHC-I) Cytoplasmic Tail and Disrupt MHC-I Trafficking in HIV-1-Infected Primary T Cells

... by major histocompatibility complex class I (MHC-I), and evidence has been accumulating that this function of Nef is important in ...of MHC-I by stabilizing a protein-protein ...

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Major Histocompatibility Complex (MHC) Genes and Disease Resistance in Fish

Major Histocompatibility Complex (MHC) Genes and Disease Resistance in Fish

... classical MHC class I molecule, identified by the peptide termini binding residues (reviewed in [35]) and in later studies by extensive allelic polymorphism, was by Grimholt et ...classical MHC class I ...

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Antibiotic therapy and outcome from immune-checkpoint inhibitors

Antibiotic therapy and outcome from immune-checkpoint inhibitors

... Lipopolysaccharide; MHC: Major Histocompatibility Complex; NOD1: Nucleotide-binding oligomerization domain-containing protein 1; NSCLC: Non-small Cell Lung Cancer; ORR: Overall response rate; ...

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Characterization of a Murine Cytomegalovirus Class I Major Histocompatibility Complex (MHC) Homolog: Comparison to MHC Molecules and to the Human Cytomegalovirus MHC Homolog

Characterization of a Murine Cytomegalovirus Class I Major Histocompatibility Complex (MHC) Homolog: Comparison to MHC Molecules and to the Human Cytomegalovirus MHC Homolog

... with m144. SDS-PAGE analysis of immunoprecipitated pro- tein from cells expressing m144 and mb2m also reveals two bands migrating at 45 and 12 kDa (data not shown). m144- mb2m was purified from transfected cell ...

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The Major Histocompatibility Complex in Song Sparrows: Immunity, Signals, and Mate Choice

The Major Histocompatibility Complex in Song Sparrows: Immunity, Signals, and Mate Choice

... intermediate MHC diversity (table ...intermediate MHC diversity had fewer parasites than those with low or high MHC ...intermediate MHC diversity had larger clutch sizes (Bonneaud et ...

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Vesicular stomatitis virus infection of the central nervous system activates both innate and acquired immunity.

Vesicular stomatitis virus infection of the central nervous system activates both innate and acquired immunity.

... of major histocompatibility complex (MHC) class I molecules on astrocytes and microglial, endothelial, and ependymal cells was also rapidly induced and followed by induced expression of ...

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Altered Expression of TAP-1 and Major Histocompatibility Complex Class I in Laryngeal Papillomatosis: Correlation of TAP-1 with Disease

Altered Expression of TAP-1 and Major Histocompatibility Complex Class I in Laryngeal Papillomatosis: Correlation of TAP-1 with Disease

... Correlation between TAP-1 and clinical course. Sixteen archival specimens were used to correlate the TAP-1 staining intensity with disease status. Ten biopsy samples of papilloma tissue were taken from patients with RRP ...

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Genomic analysis of stress, aggression and boldness in rainbow trout

Genomic analysis of stress, aggression and boldness in rainbow trout

... form complex phenotypes whose expression represents the response to a variety of influences, including genotype, external environment, emotional state and previous experience (Boake et ...and major ...

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Fine structure of a virus-encoded helper T-cell epitope expressed on FBL-3 tumor cells.

Fine structure of a virus-encoded helper T-cell epitope expressed on FBL-3 tumor cells.

... To understand peptide-major histocompatibility complex MHC interactions and the subsequent recognition of peptides by specific T cells, we used peptides of decreasing lengths to determin[r] ...

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FDA-approved immunosuppressants targeting staphylococcal superantigens: mechanisms and insights

FDA-approved immunosuppressants targeting staphylococcal superantigens: mechanisms and insights

... the major histocompatibility complex class II (MHC II) molecules and specific Vβ regions of T-cell receptors (TCRs), resulting in the stimulation of both monocytes/macrophages and T ...with ...

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Dynamics of major histocompatibility complex class II-positive cells in the postischemic brain - influence of levodopa treatment

Dynamics of major histocompatibility complex class II-positive cells in the postischemic brain - influence of levodopa treatment

... callosum; MHC II: major histocompatibility complex class II; tMCAO: transient Middle cerebral artery occlusion; FACS: fluorescence-activated cell sorting; HBSS: Hank ’ s balanced salt ...

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Equine Herpesvirus Type 1-Mediated Oncolysis of Human Glioblastoma Multiforme Cells

Equine Herpesvirus Type 1-Mediated Oncolysis of Human Glioblastoma Multiforme Cells

... human major histocompatibility complex class 1 (MHC-I) was detected in the resistant glioma line, while infection of the susceptible glioma cell lines, which expressed human MHC-I, were ...

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TARGETING TOOLS FOR A DNA VACCINE CARRIER, A DESIGN IN PREVENTION OF CANCER

TARGETING TOOLS FOR A DNA VACCINE CARRIER, A DESIGN IN PREVENTION OF CANCER

... class major histocompatibility complex (MHC) ...to MHC molecules is allele specific, and correlates their immunogenicity (Altuvia et ...especially MHC-class I mediated pathway ...

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A Novel Bat Herpesvirus Encodes Homologues of Major Histocompatibility Complex Classes I and II, C-Type Lectin, and a Unique Family of Immune-Related Genes

A Novel Bat Herpesvirus Encodes Homologues of Major Histocompatibility Complex Classes I and II, C-Type Lectin, and a Unique Family of Immune-Related Genes

... encode major histocompatibility complex (MHC)-related proteins, 2 to encode MHC class I homologues, and 3 to encode MHC class II homologues; 4 encode the homologues of C-type ...

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Kaposi's Sarcoma-Associated Herpesvirus Viral Interferon Regulatory Factor 3 Inhibits Gamma Interferon and Major Histocompatibility Complex Class II Expression

Kaposi's Sarcoma-Associated Herpesvirus Viral Interferon Regulatory Factor 3 Inhibits Gamma Interferon and Major Histocompatibility Complex Class II Expression

... of MHC II in PEL cells compared to KSHV-negative B cell ...of MHC II transcripts upon vIRF-3 ...of MHC II (HLA-DRA/B, -DPA/B, and -DQA/B) mRNA was analyzed by semiquantitative RT-PCR (HLA-DRA/B and ...

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Diminished expression of major histocompatibility complex facilitates the use of human induced pluripotent stem cells in monkey

Diminished expression of major histocompatibility complex facilitates the use of human induced pluripotent stem cells in monkey

... The future of stem cell therapy is mainly dependent on overcoming the side-effects, rather than finding their new therapeutic potentials. We had previously hypothe- sized that if iPSCs were disseminated in disease ...

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The chromosomal order of genes controlling the major histocompatibility complex, properdin factor B, and deficiency of the second component of complement

The chromosomal order of genes controlling the major histocompatibility complex, properdin factor B, and deficiency of the second component of complement

... INTRODUCTION Evidence has been presented for the linkage of the HLA histocompatibility genes HLA-A, B, C, D,1 collectively referred to as the major histocompatibility complex MHC, to the[r] ...

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The Major Histocompatibility Complex Class I Genes of Zebrafish.

The Major Histocompatibility Complex Class I Genes of Zebrafish.

... the major histocompatibility complex (MHC) were named after the discovery that they encode the primary antigens responsible for determining transplant compatibility (Klein 2001), MHC ...

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Allorecognition by T Lymphocytes and Allograft Rejection

Allorecognition by T Lymphocytes and Allograft Rejection

... allogeneic major histocompatibility complex (MHC) molecules on donor cells (direct pathway) and/or donor peptides presented by self-MHC molecules on recipient antigen-presenting cells ...

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