miR-124
NF-κB-mediated miR-124 suppresses metastasis of non-small- cell lung cancer by targeting MYO10
... with miR-124 level in NSCLC tissue biopsies (Figure ...ectopic miR-124 expressed cells revealing a significant down-regulation (Figure ...of miR-124 with ...
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Original Article MiR-124-3p inhibits PDGF-BB-induced vascular smooth muscle cell proliferation and migration through targeting STAT3
... as miR-21, miR-216, miR-217, miR-181b, miR-31b and miR-34a, which were confirmed to be upregulated in senescing human umbilical vascular endothelial cells (HUVECs) ...that ...
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Original Article MiR-124 effect in neurons apoptosis in newborn rat with thyroid hypofunction
... nmol/L miR-124 mimics solution was injected ...lows: MiR-124’-GTCGTATCCAGTGCAGGGTCCGA GGTATTCGCACTGGATACGACGGCATT-3’; U6, 5’- ...follows: miR-124, for- ward ...
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Methylation-regulated miR-124-1 suppresses tumorigenesis in hepatocellular carcinoma by targeting CASC3
... of miR-124-1 in hepatocellular carcinoma ...of miR-124-1 in human HCC tissues and cell ...expressing miR- 124-1, and proliferation and colony formation were ...overexpressing ...
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The miR 124 Sox9 paramutation: RNA mediated epigenetic control of embryonic and adult growth
... Epigenetic modulation of Kit and Cdk9 expression was induced by oligoribonucleotides with sequences of their respective transcripts as efficiently as by the cognate microRNAs (Rassoulzadegan et al., 2006; Wagner et al., ...
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AKT2 drives cancer progression and is negatively modulated by miR-124 in human lung adenocarcinoma
... AKT2. MiR-124 was found to potentially contribute to AKT2 overexpres- ...sion. MiR-124 has been reported to play critical roles in tumor formation and development in multiple can- cers, such ...
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p62 acts as an oncogene and is targeted by miR-124-3p in glioma
... whether miR-124-3p affected p62 expression at both the mRNA and protein levels, we extracted the total RNA and protein contents of U87 and U251 cells and examined them with qRT-PCR and western blot, ...
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Methylation of miR 34a, miR 34b/c, miR 124 1 and miR 203 in Ph negative myeloproliferative neoplasms
... controls. miR-34b/c were homozygously methylated in HEL cells but heterozygously in ...homozygous miR-34b/c methylation was associated with miR silencing, and 5-aza-2’-deoxycytidine treatment led to ...
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Expression Analysis of MiR 124 in Experimental Cerebral Hypoperfusion
... SH-SY5Y cells transfected with pre-miR-124 by lipidosome to overexpress miR-124. SH-SY5Y-miR-124 cells and control cells were seeded in 6 well plate and cultured 24 h. After ...
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miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells
... which miR-124 regulates differentiation and ...example, miR-124 directly targets PTBP1 (PTB/hnRNP I) mRNA, a global repressor of alter- native pre-mRNA splicing in non-neuronal cells, ...
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Drosophila miR 124 regulates neuroblast proliferation through its target anachronism
... in miR-124 -expressing neuronal ...from miR-124-Gal4- expressing neurons in miR-124 mutant versus wild-type ...in miR-124 -expressing ...in miR-124 ...
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<p>miR-124 Functions As A Melanoma Tumor Suppressor By Targeting RACK1</p>
... to miR-302 in gastric cancer cell lines and tumor tissues. 33 miR-124 and RACK1 are involved in many biological processes and regulation of ...that miR-124 and RACK1 are potential ...
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MiR-124 inhibits the migration and invasion of ovarian cancer cells by targeting SphK1
... of miR-124 substantially decreased the expression of SphK1 in both SKOV3-ip and HO8910pm ovarian cancer cells assessed by western blot assay (Figure 2D and Additional file 2C), although real-time PCR ...
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Impact of voluntary exercise and housing conditions on hippocampal glucocorticoid receptor, miR 124 and anxiety
... and miR-124 expression in single versus pair-housed animals could be due to differences in pul- satile/continuous levels of corticosterone and distance ...and miR-124 as, in the hippocampus, ...
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Original Article miR-124 regulates myocardial ischemia reperfusion injury
... overexpressed miR-30a will decrease cell autophagy induced by cisplatin, which indi- cated that miRNA plays an important regulatory role in ...that miR- 30a would reduce the autophagy flux in chronic ...
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Original Article MiR-124 inhibits neural apoptosis in ischemic stroke
... confirmed miR- 124 was up-regulated in stroke patients, and overexpression of miR-124 could be a potential therapeutic approach to improve post-stroke prognosis via enhancing proliferation and ...
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Original Article MiR-124 inhibits cell proliferation, invasion, and migration in glioma by targeting Smad2
... conserved miR-124-binding site (Figure ...of miR-124, a dual- luciferase reporter system was employed by co- transfection of miR-124 and luciferase reporter plasmids containing ...
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Original Article MiR-124 enhances cell radiosensitivity by targeting PDCD6 in nasopharyngeal carcinoma
... An immortalized nasopharyngeal epithelial cell NP69 was cultured in Keratinocyte-SFM (In- vitrogen) supplemented with bovine pituitary extract (BD Biosciences). The human NPC cell lines 5-8F, 6-10B, CNE1, CNE2, C666-1, ...
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miR 124 function during Ciona intestinalis neuronal development includes extensive interaction with the Notch signaling pathway
... predicted miR-124 targets among a wide range of canonical seed ...one miR-124 canonical site are bona fide miR-124 targets in vivo ...
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Original Article MiR-124 inhibits malignant biological behaviors of glioma cells by targeting SDCBP
... the miR-124 overexpressing group was smaller than that of the miR-NC overex- pressing ...of miR- 124 overexpression group was significantly smaller than that of miR-NC ...
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