miR-29a
<p>miR-29a inhibits proliferation, invasion, and migration of papillary thyroid cancer by targeting DPP4</p>
... The dipeptidyl dipeptidase 4 (DPP4), an adenosine deaminase complex protein, was expressed in many organs and cell types. 9 In addition, it played an important role in various pathophysiologic processes, including ...
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Novel role of miR-29a in pancreatic cancer autophagy and its therapeutic potential
... by miR-29a using four prediction algorithms (TargetScan, PicTar, PITA, and ...conserved miR-29 binding sites in their 3’-UTRs (Figure ...of miR-29a in pancreatic cancer cells resulted ...
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The role of miR-29a in the regulation, function, and signaling of liver fibrosis
... of miR-29a in the mitigation of liver fibrosis. miR-29a is a crucial regulator of the profibrogenic phenotype of ...Increased miR-29a function hinders ER stress, TLR 2, 4, HDAC4 ...
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The microRNA miR 29a is associated with human immunodeficiency virus latency
... of miR-29a and 3′UTR of HIV-1 RNA is sufficient for targeting the latter to the P bodies; the disruption of P bodies results in enhanced viral repli- cation ...creased miR-29a might target ...
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Altered expression pattern of miR-29a, miR-29b and the target genes in myeloid leukemia
... of miR- 29 family as predictive biomarkers for early diagnosis of malignancies and other diseases, however, the exprssion pattern of miR-29 in myeloid leukemia haven’t been assessed accurately and their ...
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miR-29a promotes osteoblast proliferation by downregulating DKK-1 expression and activating Wnt/β-catenin signaling pathway
... The cells were randomly divided into 4 groups: con- trol, DKK-1 overexpression, DKK-1 siRNA, and miR-29a. MicroRNA-29a mimics, DKK-1 overexpression lysates and DKK-1 siRNAs were purchased from Hanbio ...
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Original Article Negative correlation and opposite bio-functions of miR-29a and miR-425 in human gastric cancer
... two miR- NAs, we found that increased miR-425 and/ or decreased miR-29a tumors tended to be poorly differentiated and with positive lymphat- ic ...
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Original Article Knockdown of miR-29a-3p protects the injury of PC-12 cells induced by H
... of miR- 29a-3p on PC-12 cells, we examined the expression of P13K, p-P13K, AKT, p-AKT, PTEN by qRT-PCR and Western ...of miR-29a-3p inhib- ited the levels of p-P13K/P13K, p-AKT/AKT, which ...
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Effect of Continues Training and High Intensity Interval Training on miR-29a and CTGF Gene Expression in Male Wistar Diabetic Rats’ Heart Tissue
... The miR-29a implication in biological processes like fibrosis is important ...The miR-29 family members were detected to target various professional genes and their pathways, regulating fibrosis and ...
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S improves myocardial fibrosis caused by hyperthyroidism by downregulating stat pathways and regulating mir-21 and mir-29a expression
... including miR-21, and participates in the fibrosis mechanism through affecting the activity of miR-21 to regu- late MMPs/TIMPs levels [19, ...of miR-21 in myocardium and the downregulation in ...
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MiR-185/AKT and miR-29a/Collagen 1a pathways are activated in IPF BAL cells
... cells, miR-29a was significantly ...in miR-29a and miR-29c expression was significantly associated with reduced DLco ...the miR-29 family are considered major regulators in ...
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<p>MiR-29a function as tumor suppressor in cervical cancer by targeting SIRT1 and predict patient prognosis</p>
... 20,21 MiR-29a was low expression and inhibited tumorigenesis in multiple cancers, including papillary thyroid carcinoma, colorectal can- cer, glioma and pancreatic ...that miR-29a inhibited ...
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<p>TMF inhibits miR-29a/Wnt/β-catenin signaling through upregulating Foxo3a activity in osteoarthritis chondrocytes</p>
... 29 MiR-29 family has three members, including miR-29a, miR-29b, and ...of miR-29a by binding of β -catenin/TCF4/LEF1 complex to its ...17 miR-29a also modulates the ...
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Original Article miR-29a inhibits adhesion, migration, and invasion of osteosarcoma cells by suppressing CDC42
... of miR-29a (Figure ...of miR- 29a ...that miR-29a was mainly in- volved in regulating focal adhesion, negative regulation of translation, and homophilic cell adhesion through ...
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Original Article MiR-29a regulated FOXO3 expression and promoted the cell proliferation of human cervical cancer
... example, miR-29a was reported to be sig- nificantly downregulated in both cholangiocar- cinoma tissues and tumor cell lines, further- more, overexpression of miR-29a reduced the cell ...
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Modulation of a Specific Pattern of microRNAs, Including miR 29a, miR 30a and miR 34a, in Cultured Human Skin Fibroblasts, in Response to the Application of a Biofunctional Ingredient that Protects against Cellular Senescence in Vitro
... The miR-34 family is highly conserved across various organisms and is considered as a tumor suppressor gene that participates in the inhibition of cell cycle progression and the stimulation of apoptosis ...the ...
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Expression Analysis of Cellular Mir-29a and mir-29b in HIV Positive Patients
... as miR-29a and miRI-29b which are altered in the direction of disease progression, can be used to assess patients' conditions and lead the treatment ...
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Integrated analyses of microRNA-29 family and the related combination biomarkers demonstrate their widespread influence on risk, recurrence, metastasis and survival outcome in colorectal cancer
... of miR-29 family may affect the relationship between miR-29 family expression and ...the miR-29 family in CRC occurrence and development through an integrated bioinformatics ...of ...
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microRNA dysregulation in polyglutamine toxicity of TATA-box binding protein is mediated through STAT1 in mouse neuronal cells
... of miR-29a/b that leads to previously established cascade of events marked by over-expression of apoptotic genes including Vdac1, Bace1, Puma, and ...rescues miR-29a level but not ...
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Circulating miR 378 and miR 451 in serum are potential biomarkers for renal cell carcinoma
... found miR-29a and miR-92 plasma levels to dif- ferentiate between CRC patients and controls with sen- sitivity of 89% and specificity of 70% and also to be associated with clinical stage [10], (ii) ...
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