miR-30a
The Coronavirus Transmissible Gastroenteritis Virus Evades the Type I Interferon Response through IRE1α-Mediated Manipulation of the MicroRNA miR-30a-5p/SOCS1/3 Axis
... reduces miR-30a-5p ...of miR-30a-5p by TGEV (D) or Tg ...of miR-30a-5p normalized to that of internal U6 siRNA was measured by RT-qPCR after 24 ...of miR-30a-5p in ...
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Review Article Potential diagnostic value of circulating miR-30a-3p for non-small cell lung cancers: meta-analysis from microarray datasets
... confirm miR-30a-3p expression levels in ...the miR-30a-3p expression data were only extracted from microarray assays without extra confirmation by more accurate methods (for instance, real ...
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Original Article Long noncoding RNA NORAD regulates lung cancer cell proliferation, apoptosis, migration, and invasion by the miR-30a-5p/ADAM19 axis
... 15]. MiR-30a-5p was considered to be a tumor suppressor in some cancers, such as colon carcinoma [16], colorectal can- cer [17], and hepatocellular carcinoma ...the miR- 30a-5p abundance was ...
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Original Article Overexpression of miR-30a attenuates neuropathic pain by targeting SOCS1 in rats with chronic constriction injury
... of miR-30a on neurobehavioral testing. A. Relative miR-30a mRNA level in the lentivirus transduction with miR-30a and with control lentivirus; ...of miR-30a group ...
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Original Article Prospective target genes and pathways of miR-30a-5p in colorectal cancer: an investigation using TCGA and bioinformatics analysis
... that miR-30a-5p most likely modulates the pathogenesis of colorectal can- cer through the above well-studied ...of miR-30a-5p with CRC remain to be explored. Moreover, whether miR- ...
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Original Article MiR-30a regulates the atrial fibrillation-induced myocardial fibrosis by targeting snail 1
... between miR-30a along with its target gene snail 1 and atrial fibrillation (AF)-induced myocardial ...(mimics miR-30a), inhibitors group (inhibitors miR-30a), NC group ...
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Salvianolic acid B induced upregulation of miR 30a protects cardiac myocytes from ischemia/reperfusion injury
... between miR-30a and autophagy has been ...that miR-30a can negatively regulate expression of the beclin-1 gene, resulting in decreased autophagic activity in cancer cell lines such as T98G, ...
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<p>miR-30a-3p Targets MAD2L1 and Regulates Proliferation of Gastric Cancer Cells</p>
... that miR-30a-3p is the key miRNA regulating the expression of MAD2L1, in line with the results from the bioinformatics ...ndings, miR-30a-3p inhibits the proliferation of gastric cancer cells ...
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Original Article Down-regulation and clinical role of miR-30a-5p in hepatocellular carcinoma: a study based on public high-throughput datasets
... between miR-30a-5p level and differentiation grade ...the miR-30a-5p and the following parameters: gender, age, clinical TNM stage, cirrhosis, metastasis, vascular invasion, HCV infection ...
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Original Article MiR-30a-5p accelerates adipogenesis by negatively regulating Sir tuin 1
... for miR-30a-5p or SIRT1 using a TaqManTM MicroRNA Reverse Transcription kit (Thermo Fisher Scientific) or a High Capacity cDNA Reverse Transcription Kit (Thermo Fisher ...
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Original Article miR-30a inhibits breast cancer progression through the Wnt/β-catenin pathway
... of miR-30a in 114 samples of BC tissues was significantly lower than it was in adjacent para- cancerous normal tissues, and was related to the tumor diameter, histological grade, lymph node metastasis, TNM ...
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Clinicopathological role of miR-30a-5p in hepatocellular carcinoma tissues and prediction of its function with bioinformatics analysis
... of miR- 30a-5p in the progression of HCC, the validated target genes of miR-30a-5p from literature screening were collected from PubMed, Wiley Online Library, Web of Science, Science Direct, ...
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A Yin Yang 1/miR 30a regulatory circuit modulates autophagy in pancreatic cancer cells
... that miR-30a might negatively be reg- ulated by ...the miR-30a genomic loci ...the miR-30a 3 ′ UTR compared to the negative ...the miR-30a 3 ′ UTR showed unchanged ...
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Circulating miR-30a, miR-126 and let-7b as biomarker for ischemic stroke in humans
... Background: Recently, plasma miRNAs have been reported as biomarkers for various diseases. However, the knowledge on the association of plasma miRNAs with ischemic stroke is still lacking. In this study, we investigated ...
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Modulation of a Specific Pattern of microRNAs, Including miR 29a, miR 30a and miR 34a, in Cultured Human Skin Fibroblasts, in Response to the Application of a Biofunctional Ingredient that Protects against Cellular Senescence in Vitro
... (miR-146a-5p, miR-155-5p, miR-21-5p, miR-542-5p) showed RQ values higher than ...(miR-10b-5p, miR-1185-5p, miR-143-3p, miR-145-5p, miR-199a-3p, ...
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miR-30a suppresses osteosarcoma proliferation and metastasis by downregulating MEF2D expression
... (A) mir-30a expression by transfection with mir-30a mimic and mir-30a inhibitor in Mg-63 ...of mir-30a on cell proliferation of Mg-63 ...of mir-30a on ...
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Original Article MiR-30a-5p suppresses cell growth and enhances apoptosis of hepatocellular carcinoma cells via targeting AEG-1
... of miR-30a-5p was first detected with real time RT-qPCR and the transfection efficiency was confirmed to be optimal (data not ...of miR-30a-5p on cell growth was identi- fied with three ...
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miR-30a as Potential Therapeutic by Targeting TET1 through Regulation of the Hydroxymethlation of Drp-1 Promoter in IPF
... more miR-30 family members include Xlim1/Lhx1 [16], Snail1 [17], BCL6 [18], p53 [19], and RUNX2 ...of miR-30a and the regulatory mode between TET1 and ...that miR-30a could act as a ...
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Bioinformatics prediction of miR-30a targets and its inhibition of cell proliferation of osteosarcoma by up-regulating the expression of PTEN
... of miR-30a and PTEN was obviously decreased in MG-63, 143B and Saos-2 cells compared with primary ...showed miR-30a might bind with position 30-57 of 3 ’ UTR of ...with ...
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CirculatingMiR-10b, MiR-1 and MiR-30a Expression Profiles in Lung Cancer: Possible Correlation with Clinico-pathologic Characteristics and Lung Cancer Detection
... This study suggested that miR-10b, miR-1 and miR-30a, could be considered as helpful diagnostic signatures in NSCLC patients. This classifier is fairly new and could have important molecular ...
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