miRNA/miR
Attribution of vascular phenotypes of the murine Egfl7 locus to the microRNA miR 126
... 2008). miR-126 (Mirn126 – Mouse Genome Informatics) is an endothelial miRNA residing within intron 7 of Egfl7, resulting in pan-vascular developmental coexpression of miR- 126 and Egfl7 and their ...
5
Identification and characterization of microRNAs expressed in the African malaria vector Anopheles funestus life stages using high throughput sequencing
... redundant miRNA reads revealed that expression varies significantly among different ...insect-specific miRNA (miR-263a) was found to be the most abundant ...However, miR-8 was the common ...
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Dysregulated miRNA Associated with Transcription Factors of Insulin Gene Expression in Chronic Pancreatitis
... Among the 25 differentially expressed miRNA, a few clusters of miRNA miR-29a/29b/29c, miR-200a/200b/200c/141, miR-216/217, miR-30a/30b/30c, miR-27a/27b/24/23b were noted to be associated[r] ...
24
Antisense therapeutics in oncology: current status
... downregulated miRNA response elements inserted immediately after the stop codon of the selected genes was noted to be effective in controlling the expression of TRAIL in cancer cells when compared to the ...
8
miR-486 is modulated by stretch and increases ventricular growth
... stretch-responsive miRNA miR-486 is sufficient to promote ventricular growth, demonstrates that this miRNA is sufficient to increase ventricular growth in vivo, and shows that it is a potentially ...
18
MiRNA-145 increases therapeutic sensibility to gemcitabine treatment of pancreatic adenocarcinoma cells
... over-expressing miR-145 or negative control miRNA (miR-NC) were established using lentivirus carrying miR-145 or miR-NC, and verified by detecting the expression of miR-145 ...
12
<p>MiR-27a-3p Targeting GSK3β Promotes Triple-Negative Breast Cancer Proliferation and Migration Through Wnt/β-Catenin Pathway</p>
... NC, miR-27a-3p mimic and inhibitor) and the low chambers were fi lled with culture medium as chemoattractant and then stay for 2 days, migrated cells on the lower chambers were fi xed with 4% paraformaldehyde and ...
9
Serum microRNA array analysis identifies miR-140-3p, miR-33b-3p and miR-671-3p as potential osteoarthritis biomarkers involved in metabolic processes
... hsa- miR-671-3p, and U6 small nuclear RNA (RNU6B) stem- loop RT primer to generate the cDNA as previously de- scribed ...[30]. MiRNA expression was verified by ...each miRNA. For the quantification ...
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Prospective validation of microRNA signatures for detecting pancreatic malignant transformation in endoscopic-ultrasound guided fine-needle aspiration biopsies
... both miR-21 and miR- 155 were strong independent predictors of pancreatic malignancy when up-regulated in EUS-FNAs (P < ...the miR-21 + miR-155 classifier had excellent accuracy for ...
14
Original Article Array profiling identified dysregulated miRNAs and target genes and pathways in laryngeal squamous cell carcinoma
... functional miRNA-gene-network and miR- NA-pathway-network relation- ships with a high ...screened miR- NAs, hsa-miR-30a-5p should be paid attention to. Hsa-miR- 30a-5p was ...
11
Involvement of methylation of MicroRNA-122, −125b and -106b in regulation of Cyclin G1, CAT-1 and STAT3 target genes in isoniazid-induced liver injury
... of miRNA expres- sion. miR-122 was one of the most abundant miRNAs in the liver, accounting for up to 72% of all hepatic miRNAs [12], while the expressions of miR-106b and miR-125b not only ...
13
MicroRNA 181b regulates NF κB–mediated vascular inflammation
... whether miR-181b regulates NF-κB translocation in vivo, miR-181b was systemically administered by tail-vein injection, and mice were challenged with or without ...delivered miR-181b compared with ...
19
Urinary miRNA profile for the diagnosis of IgA nephropathy
... high-throughput miRNA profiling and identified 37 miRNAs that were differentially expressed in the peripheral blood mononuclear cells (PBMC) of patients with IgA nephropathy as compared to healthy ...PBMC ...
8
MicroRNA biomarker identification for pediatric acute myeloid leukemia based on a novel bioinformatics model
... the miR-29 family. A comprehensive study investigated all members of the miR-29 family, including miR-29a, -29b and ...the miR-29 family during AML development results in the upregulation of ...
13
Are Changes in MicroRNAs Expression A Relevant Biomarker for Urinary Bladder Cancer Prognosis?
... 126 and miR-139) in our patients. The present approach aims to figure the possibility of defining an epigenetic molecular diagnosis algorithm. Moreover, the new results establish the tumorigenic role (as tumor ...
8
Silencing of microRNA 101 prevents IL 1β induced extracellular matrix degradation in chondrocytes
... after miRNA transfection and IL-1b ...only miR-101 could bind to the 3 ’ UTR of ...by miR-101 in rat chondrocytes. Functional analysis showed that miR-101 could aggravate chondrocyte ECM ...
11
MicroRNA signatures in vitreous humour and plasma of patients with exudative AMD
... in miR-146a and a decrease in miR-106b and miR-152 in the vitreous humour which was reproducible in ...Moreover, miR-146a/miR-106b ratios discriminated patients with NV AMD with an area ...
14
Kaeuferle, Theresa (2015): Identification of microRNAs regulating adipocyte differentiation via mTOR nutrient-signaling. Dissertation, LMU München: Fakultät für Chemie und Pharmazie
... study miR-183 did not influence lipid droplet deposition, but revealed an attenuating effect on adipocyte differentiation as evidenced by its influence on adipocyte/pre-adipocyte marker gene expression at late ...
83
The Function of miR 31 Expression in Differentiation of Neural Stem Cells
... of miR-31 related to cancer. Compared with normal tissues, miR-31 up-regulated at head and neck cancer (Wong et al, 2008) [7], colorectal cancer (motoyama et al, 2009; wang CJ et al, 2009) [8] [9], lung ...
8
The Role of MicroRNA in Paediatric Acute Lymphoblastic Leukaemia: Challenges for Diagnosis and Therapy.
... 2.7. miRNA and Late Effects of ...plasma miRNA and to correlate these changes to known markers of cardiac injury, a prospective cohort study was performed on chil- dren receiving AC chemotherapy ...plasma ...
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