mouse embryo fibroblasts
Alphavirus Minus-Strand Synthesis and Persistence in Mouse Embryo Fibroblasts Derived from Mice Lacking RNase L and Protein Kinase R
... synthesis. Mouse embryo fibroblasts (MEF) from Mx1-deficient mice that also lack either the protein kinase R (PKR) or the latent RNase L or both PKR and RNase L were ...
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Induction of Alpha/Beta Interferon by Myxoma Virus Is Selectively Abrogated When Primary Mouse Embryo Fibroblasts Become Immortalized
... primary mouse embryo fibroblasts (pMEFs) are resistant to productive myxoma virus infection, a phenotype congruent with the noninfectivity of the virus in vivo ...
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Cellular Transformation of Mouse Embryo Fibroblasts in the Absence of Activator E2Fs
... The E2F family of transcription factors, broadly divided into activator and repressor E2Fs, regulates cell cycle genes. Current models indicate that activator E2Fs are necessary for cell cycle progression and ...
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The ability of simian virus 40 large T antigen to immortalize primary mouse embryo fibroblasts cosegregates with its ability to bind to p53.
... We examined several mutants with small insertions or deletions within the 347 to 626 region and found perfect cosegregation between the abilities of these mutant large T antigens to immo[r] ...
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Characterising Mutational Spectra of Carcinogens in the Tumour Suppressor Gene TP53 Using Human TP53 Knock-in (Hupki) Mouse Embryo Fibroblasts
... Abstract: DNA in dividing cells is prone to mutagenesis, with mutations making key contributions to human disease including cancer. The tumour suppressor gene TP53 is the most frequently mutated gene in human tumours. ...
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Electron Microscopic Studies of Tumor Viruses I. Entry of Murine Leukemia Virus into Mouse Embryo Fibroblasts
... At the site of viral attachment to the cell membrane, three distinct interactions occurred between the viral envelope and cell membrane, namely, i dissolution of viral envelopes on the c[r] ...
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The function of CUX1 in oxidative DNA damage repair is needed to prevent premature senescence of mouse embryo fibroblasts
... RNAi-mediated knockdown and gene inactivation demonstrated that CUX1 is required for efficient repair of oxidative DNA damage, while base excision repair assays established that Cut repe[r] ...
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5543.pdf
... Cell lines and plasmids: CRC cell lines were obtained from ATCC and maintained in either DMEM-H or RPMI-1640 supplemented with 10% fetal calf serum, and frozen down to maintain limited passage history. Lentivirus vectors ...
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The Adhesion Modulating Properties of Tenascin-W
... of mouse embryo fibroblasts when compared with cells cultured on fibronectin ...Dermal fibroblasts har- vested from a tenascin-C knockout mouse express tenascin-W, but dermal ...
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Endogenous ecotropic mouse type C viruses deficient in replication and production of XC plaques.
... N-tropic viruses that were induced from C58 mouse embryo fibroblasts MEF were transmitted to cells with high efficiency and formed large XC plaques, whereas N-tropic virus derived from B[r] ...
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Synthesis and Antiproliferative Evaluation of New Aminoisoquinolinequinones Derived from p Phenylenediamine, Benzidine and Dapsone
... primary mouse embryo fibroblasts cell line MEF and three cancer cells lines: MDA-MB-21 human breast adenocarcinoma, B16-F10 murine metastatic melanoma and Caco-2 human colorectal adencarcinoma cells, ...
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Papillomavirus Infection Requires γ Secretase
... the mouse genital tract by human papillomavirus type 16 (HPV16) ...and mouse embryo fibroblasts deficient in any one of these components were not infected by HPV16, whereas wild-type and  ...
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Simian virus 40 small t antigen activates the carboxyl-terminal transforming p53-binding domain of large T antigen.
... The importance of complex formation between large T and p53 for SV40-mediated cellular transformation is firmly estab- lished (16, 23, 52, 56, 59, 73, 74), although the functional consequences of this interaction are not ...
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Regulation of redox metabolism in the mouse oocyte and embryo
... The pyridine nucleotides NADH and NADPH and the thiol tripeptide glutathione ( ␥ -glutamylcysteinylglycine, GSH) form the vast majority of the reducing equivalents available in the cell. GSH is the major antioxidant ...
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Different thresholds of fibroblast growth factors pattern the ventral foregut into liver and lung
... of mouse embryos at five- (B) and seven- (C) somite stages, demonstrating the onset and expansion of FGFR4 protein expression (arrows) in the foregut (fg) relative to the cardiac domain (cm); (A) adjacent section ...
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Roughness threshold for cell attachment and proliferation on plasma micro-nanotextured polymeric surfaces: The case of primary human skin fibroblasts and mouse immortalized 3T3 fibroblasts
... Bourkoula, A, Constantoudis, V, Kontziampasis, D orcid.org/0000-0002-6787-8892 et al. (4 more authors) (2016) Roughness threshold for cell attachment and proliferation on plasma micro-nanotextured polymeric surfaces: The ...
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Mouse peritoneal cells confer an antiviral state on mouse cell monolayers: role of interferon.
... The above experiments showed that the capacity of peritoneal cells to confer an antiviral state on target monolayer cultures of mouse embryonic fibroblasts or aged mouse macrophages was [r] ...
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Vasculogenesis and angiogenesis in the mouse embryo studied using quail/mouse chimeras
... Mouse explants were dissected from the host coelom together with the surrounding tissue where they had implanted. They were fixed overnight in AFA (60% ethanol, 30% formaldehyde, 10% acetic acid). After ethanol ...
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Stochastic patterning in the mouse pre implantation embryo
... the embryo, whereas ‘outside’ cells have such contact (white arrowheads in Figs 3-5 point to examples of inside blastomeres; green arrowheads mark outside blastomeres of special interest; see also Movies 1 and 2 ...
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Active cell migration drives the unilateral movements of the anterior visceral endoderm
... In 12 of the 27 embryos that developed normally, we were able to discern individual cells of the AVE in great detail as they moved to the prospective anterior of the embryo. AVE cells at the distal tip of the ...
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