Myoepithelial Cell
The mammary myoepithelial cell
... epithelial cell markers, the absence of ER- and PR-positive cells and the lack of HER2 ...this cell population might be at the origin of basal-type BRCA1-mammary carcinomas (Lim et ...basal cell ...
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TGF-β1 stimulates epithelial–mesenchymal transition and cancer-associated myoepithelial cell during the progression from in situ to invasive breast cancer
... associated myoepithelial cells were also assessed through myoepithelial cell phenotypic markers (Calponin, SMA, ...MCF-7. Cell-based assays were carried out to document the cascade of ...
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Cell clusters overlying focally disrupted mammary myoepithelial cell layers and adjacent cells within the same duct display different immunohistochemical and genetic features: implications for tumor progression and invasion
... of myoepithelial disruptions and the precursor of invasion, we have carried out a number of studies focusing on the physical and func- tional correlation between epithelial and surrounding myoepithelial ...
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The Myoepithelial Cell Layer May Serve As a Potential Trigger Factor for Different Outcomes of Stage-Matched Invasive Lobular and Ductal Breast Cancers
... The myoepithelial cell layer is the sole source of a number of tumor suppressors, including maspin, p63, and Wilms’ tumor 1 (WT-1), which display sig- nificant inhibition on proliferation and invasion of ...
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Glucocorticoids promote transition of ductal carcinoma in situ to invasive ductal carcinoma by inducing myoepithelial cell apoptosis
... promotes myoepithelial cell apoptosis, lead- ing to disruption of the myoepithelial cell layer, favouring cell invasion and fostering progression from DCIS to ...the ...
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Loss of amphiregulin reduces myoepithelial cell coverage of mammary ducts and alters breast tumor growth
... and myoepithelial cell coverage is reduced in the ...where myoepithelial coverage is lower, giving rise to the observed multifocal ...both myoepithelial coverage and growth factor expression ...
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The importance of being a myoepithelial cell
... basal cell-specific promoters, such as those of the K5 and K14 genes, are often used to create trans- genic mice for studies of developmental processes in the epidermis and hair ...differentiated ...
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The myoepithelial cell: its role in normal mammary glands and breast cancer
... luminal cell function and mam- mary gland development may result from the direct effect of the cells via integrins and cadherins of cell- -cell junctions but may also be caused by the para- crine ...
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Myoepithelial cells: good fences make good neighbors
... and myoepithelial cells [81,82]. If myoepithelial cells are derived from a bipotential cell, then what pathways stimulate myoepithelial fate? Using the mammosphere culture system, Dontu and ...
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Epithelial-myoepithelial carcinoma of the lung: a case report
... and myoepithelial anaplasia in the EMC in salivary glands were predictors of decreased disease-free survival ...showed myoepithelial cell-predominant features with anaplasia [3, ...of ...
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Infiltrating myoepithelial carcinoma of the breast, a case report and cytologic-histologic correlation
... spindle cell lesions of the breast exist, translating into an accordingly wealthy number of differ- ential diagnoses for a cytologic specimen displaying a pre- dominant population of spindle ...17 ...
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Cells of human breast milk
... and myoepithelial cells and their precursors represent nearly 98% of the non-immune cell types in human milk under healthy ...cells. Myoepithelial cells build smooth muscle fibers surrounding the ...
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Myoepithelioma (Myoepithelial Carcinoma) of the Breast: Case Reports
... Malignant myopepitheliomas have high mitotic rates (11 – 14 / 10 HPF) diffusely through the tumour with foci of cytologically malignant cells. It was found that the myoepitheliomas that metastasized had infiltrative ...
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Breast adenomyoepithelioma: a case report with malignant proliferation of epithelial and myoepithelial elements
... in myoepithelial cells ...distinct myoepithelial cell, which lacks expression of SMA and in some cases also lacks CK5, CK14, and CK17 [3], indicating that a hier- archical differentiation pattern may ...
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Expression of Glycolysis Related Proteins in Solid Papillary Carcinoma of the Breast According to Basement Membrane Status
... to myoepithelial cell and basement membrane ...positive myoepithelial cells in the outer surface of the tumor nodule (arrow) and a basement membrane that is positive for type IV colla- gen ...
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umi-unc-3022.pdf
... the cell lineage markers keratin 8 and 18 that are normally expressed in the mammary luminal epithelial ...mammary myoepithelial cell markers, keratins 5 and ...
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Developmental stratification of the mammary epithelium occurs through symmetry breaking vertical divisions of apically positioned luminal cells
... daughter cell located between the polarized luminal and myoepithelial cell ...to cell division, through time-lapse imaging of organoids expressing ...apical cell divisions, ZO-1-GFP ...
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Case Report Clinicopathological characterization of adenoid cystic carcinoma of the esophagus: a case report and literature review
... outer myoepithelial cells expand- ed to whole tumor cell ...tumor cell mass was predominantly accompanied by P63- positive ...of myoepithelial cell markers such as CD10 (Figure 4A), ...
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NUT Carcinoma of the Salivary Glands: Clinicopathologic and Molecular Analysis of 3 Cases and a Survey of NUT Expression in Salivary Gland Carcinomas.
... Coulter GmbH), synaptophysin (clone SY38, 1:50, Dako), SMARCB1 (MRQ-27, 1:50, Zytomed), and anti-NUT antibody (clone C52B1, 1:45, Cell Signaling). Interpretation of results of the NUT IHC was based on published ...
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Mn2+ Ions Pass Through Ca2+ Channels in Myoepithelial Cells
... The results show that the myoepithelial cells of the proventriculus are capable of undergoing regenerative activity, that the overshooting spikes elicited both by transmitter substance a[r] ...
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