Non-protein-coding RNAs
Expression of non-protein-coding antisense RNAs in genomic regions related to autism spectrum disorders
... Autism spectrum disorders (ASD) are heterogeneous neurodevelopmental disorders, both in terms of clinical manifestations and genetic risk factors [1]. Disease fre- quency among siblings of affected children is approxi- ...
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Beyond the proteome: non coding regulatory RNAs
... new non-protein-coding tran- scripts, with diverse functions, have been identified ...[9-11]. Non-coding RNA transcripts are heterogeneous and do not have a single specific ...term ...
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Global Human Health Risks for Arthropod Repellents or Insecticides and Alternative Control Strategies
... long non-protein coding RNAs (lncRNAs) in primary human ...neighboring protein-coding genes, and functionally characterized via gene ontology and molecular mapping ...
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cncRNAs : Bi functional RNAs with protein coding and non coding functions
... DM protein kinase (DMPK) expressed in tissues affected by myotonic dystrophy ...DMPK protein and/or SIX5 encoded by the downstream gene leads to delayed onset of mild symptoms, but were not found to be ...
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The function of non coding RNAs in genomic imprinting
... understanding the potential roles played by histone modifications in restricting expression of macro ncRNAs to one parental allele and imprinted protein-coding genes to the other allele. Recent studies have ...
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Novel classes of non coding RNAs and cancer
... 2) protein is widely expressed in tumors and inhibits apoptosis through activation of STAT3/BCL-X(L) signalling path- ...this protein forms a PIWIL2/STAT3/c-Src complex, where STAT3 is phosphorylated by ...
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CncRNAs : RNAs with both coding and non coding roles in development
... the coding and non-coding activities of cncRNAs is also evident, and has been found for osk, vegt and sqt RNAs, with the non-coding activity detected at earlier developmental ...
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Identification and characterization of the gene expression profiles for protein coding and non-coding RNAs of pancreatic ductal adenocarcinomas
... Interestingly, in addition to the common GEP, the two subgroups of PDAC here identified also showed clearly different GEPs. Thus, enrichment in genes involved in the innate and adaptative immune response was ...
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Encoding activities of non-coding RNAs
... the protein basic local alignment search tool (BLAST) ...of non-coding regions in the genome, repeat sequences are also often transcribed as ncRNAs ...misfolded protein are characteristic of ...
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Non-coding RNAs in cardiac regeneration
... heart. Non-coding RNAs (ncRNAs), including microRNAs (miRNAs, miRs) and long non-coding RNAs (lncRNAs), are functional RNA molecules without a protein coding ...
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Long non-coding RNAs in ovarian cancer
... of protein-coding RNAs and ...of non-protein-coding transcripts may be viewed as in- consequential transcriptional “noise” or ...
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Long non coding RNAs display higher natural expression variation than protein coding genes in healthy humans
... Relatively small numbers of mammalian lncRNAs have been assigned a function. A new functional lncRNA data- base lists only 181 human transcripts (http://www.lncrnad b.org/, [31]). While it is possible that some lncRNA ...
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Long non-coding RNAs in normal and malignant hematopoiesis
... nearby protein- coding ...a protein coding gene whose transcription is initiated less than 1000 base pairs away; (4) intronic, when it is derived from within an intron of a different ...
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Non coding RNAs in muscle differentiation and musculoskeletal disease
... mRNA–binding protein 2 (IMP2) and to perturb the translational control mediated by this factor on mRNAs involved in proliferation, such as N-Ras and c-Myc ...
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Natural genetic variation of the cardiac transcriptome in non diseased donors and patients with dilated cardiomyopathy
... and non-diseased controls and identified 228 protein-coding genes and 53 noncoding RNAs with significant expression differences and fold changes of at least 20% (Additional files 2 and ...and ...
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Ribosome profiling reveals resemblance between long non coding RNAs and 5′ leaders of coding RNAs
... potential coding sequences is ribosome profiling (Ingolia et ...to protein-coding genes and might encode ...stable protein products (Bánfai et ...
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Network analysis of KLF5 targets showing the potential oncogenic role of SNHG12 in colorectal cancer
... Long non-coding RNAs (lncRNAs) are transcripts that consist of more than 200 nucleotides and have limited to no protein-coding capacity ...
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Androgen responsive intronic non-coding RNAs
... androgen-responsive non- coding intronic RNAs, we used a custom-built spotted cDNA microarray enriched in intronic transcribed sequences and a prostate cancer cell line (LNCaP) cul- tured in the ...
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Non-Coding RNAs in Bacteria
... of non-coding RNA considered cis-encoded elements of RNA, located mostly in the 5'UTR region of a target mRNA and less frequent at the 3 'end UTR [7, 42, ...regulating protein PrfA in Listeria ...
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A subset of conserved mammalian long non coding RNAs are fossils of ancestral protein coding genes
... a protein-coding gene into a lncRNA, as various scenarios are possible ...of coding potential occurred first, perhaps with the aid of compensation offered by other homologs from the same family, and ...
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