Noncoding DNA
Polymorphism of Unique Noncoding DNA Sequences in Wild and Laboratory Mice
... T h e h pattern so common among the inbred strains has thus far been found only in wild mice from Australia; it is absent in all the European wild mouse populations that [r] ...
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Possible role of natural selection in the formation of tandem-repetitive noncoding DNA.
... Two properties of the simulated tandem-repetitive structures were explored in this paper: the tendency to longer repeat units and larger sequence heteroge- neity between repeats wi[r] ...
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Meiotic recombination, noncoding DNA and genomic organization in Caenorhabditis elegans.
... CIVARDI et al. We also conclude that central clusters are discrete physical enti- ties with similar properties in terms of size, gene density and recombination rates, and pre[r] ...
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LENGTH MUTATIONS IN HUMAN MITOCHONDRIAL DNA
... The correlation between number of inferred mutations (Table 1) and the incidence of short repeated sequences in noncoding DNA is approximate at best. The implication is tha[r] ...
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Central Dogma, Selfish DNA and Noncoding RNAs: A Historical Perspective
... of DNA as the genetic material and finally the elucidation of the double helical structure of DNA in 1940s and early 1950s set the stage for emergence of molecular ...from DNA to proteins, Crick ...
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Pseudo DNA Sequence Generation of Non Coding Distributions Using Variant Maps on Cellular Automata
... many DNA sequencing projects are developed on cells, plants and animals over the world into huge DNA ...large noncoding RNAs (lncRNAs), interact with chromatin regulatory complexes, and are thought ...
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21_Lecture_Presentation_PC.ppt
... Eukarya Genome size Number of genes Gene density Introns Other noncoding. DNA Very little[r] ...
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Bringing Homologies Into Focus
... in DNA—can be a homology. Coding and noncoding DNA sequences, the proteins and gene regulation systems encoded by DNA sequences, simple traits (like eye color), compo- nents of complex organs ...
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Segmentation of DNA into Coding and Noncoding Regions Based on Recursive Entropic Segmentation and Stop Codon Statistics
... Heterogeneous DNA sequences can be partitioned into homogeneous domains that are comprised of the four nucleotides A, C, G, and T and the stop ...on DNA sequences using Jensen-Shannon and Jensen-R´enyi ...
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Integration of New Genes into Cellular Networks, and Their Structural Maturation
... T HE established view is that new genes evolve primarily by duplications and recombination, i.e., by reorganiza- tion of existing domains of other genes (Long et al. 2003; Kaessmann 2010). Recent studies, however, ...
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Role of a single non coding nucleotide in the evolution of an epidemic African clade of Salmonella
... emerged sequence type that is causing a devastating epidemic of bloodstream infections across sub-Saharan Africa. Analysis of hun- dreds of Salmonella genomes has revealed that ST313 is closely re- lated to the ST19 ...
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Regulation of DNA Double-Strand Break Repair by
... Long noncoding RNA LINP1 regulates repair of DNA double-strand breaks in. 780[r] ...
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Gammaherpesvirus Small Noncoding RNAs Are Bifunctional Elements That Regulate Infection and Contribute to Virulence In Vivo
... To generate ␥ HV68 recombinants lacking the expression of all eight TMERs, we next used bacterial artificial chromosome (BAC)-based recombination employing a two-step Red-mediated recombination protocol (27, 28). By ...
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Relaxed Selection Drives a Noisy Noncoding Transcriptome in Members of the Mycobacterium tuberculosis Complex
... lated region (5= UTR)-associated regulatory elements across an entire genome. The discovery of copious numbers of TSSs not obviously associated with mRNA transcripts in a number of stud- ies has led to an explosion in ...
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Landscape of tumor suppressor long noncoding RNAs in breast cancer
... Third, DNA methylation and histone methylation modification led to the downregulation of TSLNR expression in breast cancer, further suggesting that DNA methylation inhibitors or histone methylation ...
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Long noncoding RNAs coordinate functions between mitochondria and the nucleus
... LncRNAs are emerging as new players in gene regula- tion, but how lncRNAs operate in the regulation of an intense cross-talk between nucleus and mitochondria is still unclear. Because mitochondrial biological activities ...
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Genome wide computational analysis of potential long noncoding RNA mediated DNA:DNA:RNA triplexes in the human genome
... GA-rich DNA motif leading to disruption in Polycomb occupancy thereby regulating the chromatin state ...with DNA, rather har- nesses the sequence-specific YY1 transcription factor to attach to sites in the ...
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Long noncoding RNA mediated maintenance of DNA methylation and transcriptional gene silencing
... of noncoding RNA (ncRNA) (Kapranov et ...with DNA and chromatin-modifying enzymes, establish transcriptional gene silencing over chromosomal domains or chromosomes (Sleutels et ...
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Characterization Of The Nanci-Nkx2.1 Locus: A Novel Role For Lncrnas In Buffering Transcription Factor Expression
... Long noncoding RNAs (lncRNA) are capable of regulating gene transcription and other complex biological processes. However, the role of lncRNAs in vivo, especially within the contexts of lung development and ...
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Analysis of human papillomavirus type 16 late mRNA 3' processing signals in vitro and in vivo.
... Analysis of the published HPV-16 DNA sequence 26 indicates that the prototype HPV-16 noncoding region NCR contains three putative late mRNA 3' processing sites LP1, LP2, and LP3 which, i[r] ...
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