nucleic acid
Molecular Beacons of Xeno-Nucleic Acid for Detecting Nucleic Acid
... [62] nucleic acid capture ...electrochemical nucleic acids probe made of PNA which exhibits high sensitivity and specificity when challenged with heterogeneous samples of ...
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A Scoring Method for the Clustering of Nucleic Acid Sequences
... The clustering of biological sequence data i s a significant task for biologists. The reason is that sequence clustering assists molecular biologists to group sequences based on the ancestral traits or hereditary ...
9
Engineered biomaterials for development of nucleic acid vaccines
... the nucleic acid vaccine, some strategies were developed to prompt the permanence and efficiency of the immune responses, including physical methods (such as electroporation, sonoporation and ...
9
Nucleic Acid (Patent EP 1984502 B1)
... a nucleic acid sequence which encodes ∆9-elongase activity as set out above, operably linked with one or more regulatory ...the nucleic acid sequence which encodes ∆9-elongase and optionally ...
69
Selective tissue targeting of synthetic nucleic acid drugs
... interest, nucleic acid drugs must adhere to cell surface proteins, which can assist their cellular entry via endocytic processes (Figure 2 and ...double-stranded nucleic acids have poor cell uptake ...
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Analysis, Design, and Construction of Nucleic Acid Devices
... Given the previously developed tools for the analysis and design of nucleic acid secondary structures, the challenge is to parlay these techniques into useful DNA systems. To this end, we must first ...
172
Developing nucleic acid-based electrical detection systems
... for nucleic acid- based electrical detection has resulted in the construction of microchips and microarrays that contributed to micro- fluidic systems ...chip-based nucleic acid detection in ...
8
Nucleic acid detection in the diagnosis and prevention of schistosomiasis
... Accurate surveillance and diagnosis play key roles in the prevention and control of schistosomiasis. Firstly, in- formation on snail infection and cercariae distribution is required in order to evaluate the risk of ...
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Structural transformation induced by locked nucleic acid or 2′–O-methyl nucleic acid site-specific modifications on thrombin binding aptamer
... Locked nucleic acid (LNA) and 2' – O-methyl nucleic acid (OMeNA) are two of the most extensively studied nucleotide derivatives in the last ...
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Functional nucleic acid probes and uses thereof
... functional nucleic acid probes, and methods of using functional nucleic acid probes, for binding a target to carry out a desired ...functional nucleic acid, at least one ...
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In Vitro Selection of Functional Nucleic Acid Sequences
... catalytic nucleic acid, such that the sequence is biased towards the wild-type by only a partial randomization at each nucleotide position ...the nucleic acid. Since each selected functional ...
9
Computational design of nucleic acid feedback control circuits
... general nucleic acid circuits including ones built using the DNA Toolbox 15 and genelet approaches 16 (see Supporting Information for details), as well as the modi fi ed enzymatic strategies we proposed in ...
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Search for a Prion-Specific Nucleic Acid
... modify nucleic acids suggested that the putative genome of the prion was either quite small or did not ...modify nucleic acids than the sturdiest ...prion-specific nucleic acid using ...
11
An Introduction to Peptide Nucleic Acid
... PNA/nucleic acid duplex leaves the T m largely independent of salt concentration (Figure 3) ...a nucleic acid target despite the presence of competing secondary structure ...
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Peptide Nucleic Acid Microarrays
... A fast and economical procedure for the production of peptide nucleic acid (PNA) microarrays is presented. PNA oligomers are synthesized in a fully automatic manner in 96-well plates using standard Fmoc ...
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Nucleic acid changes during soybean leaf senescence.
... leaf senescence. Attempts have been made to chemically regulate senescence in excised and intact plants and plant parts, with growth regulators, like kinetin, gibberellic acid and more recently with several growth ...
69
Algorithms for nucleic acid sequence design
... thermodynamic nucleic acid design a high-quality, versatile, and low-cost technology that is easy to use and easily ...of nucleic acids that also achieves high-quality sequence for low cost with ...
97
Thermal and Radiochemical Analysis of Some Nucleic Acid Complexes
... Barbituric acid derivatives are well-known class of compounds where many of which are widely used as drugs having pharmacological activities as depressants, hypnotics and stimulants ...some nucleic ...
21
Detection of BCR-ABL T315I mutation by peptide nucleic acid directed PCR clamping and by peptide nucleic acid FISH
... peptide nucleic acid (PNA) technology coupled to immunofluorescence microscopy (PNA-FISH) for the specific detection at a single cell level of BCR-ABL T315I mutation thus improving both, diagnostic ...
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PNA Biosensors for Nucleic Acid Detection
... The use of nucleic acid recognition layers represents a relatively new and exciting area in biosensor technology (1-3). In particular, DNA hybridization biosensors offers considerable promise for obtaining ...
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