Oral controlled-release formulations
Design And Development Of Oral Controlled Release Formulations Of Gliclazide Using Natural Polymers
... Gliclazide release from the microspheres was studied in phosphate buffer (pH ...Gliclazide release from the microspheres was found slow which was controlled over extended period and release ...
10
Oral mucoadhesive microcarriers for controlled and extended release formulations
... of oral conventional dosage forms in multiple daily dosing produces wide ranging fluctuations in drug concentration in blood stream and tissues with consequent undesirable toxicity and poor performance associated ...
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Formulation and evaluation of Losartan Potassium matrix tablets for oral controlled release
... Table 1 enlists the composition of different formulations prepared using varying amounts of the polymers (i.e. Carbopol 934P and HPMC K4M) and dicalcium phosphate as the diluent, along with the fixed quantity of ...
6
Development and evaluation of liquid oral controlled release systems for Losartan potassium
... As losartan potassium is freely soluble in acidic media, the aim of this step was to produce SD with polymeric carrier that has limited solubility in the acidic environment. Eudragit L100 is known to have a pH-dependent ...
8
Pharmacokinetics of A New Oral Controlled-Release Formulation of Doxycycline Hyclate for Dogs
... The pharmacokinetics parameters are summarize in Table 1. The best fit for all formulations was a first order mono-compartmental model. Table 1 shows AUC, AUC ∞, RT and half-life (K½el) did not show statistically ...
6
Optimization of Polymer Concentration for Designing of Oral Matrix Controlled Release Dosage Form
... drug release exponent ...drug release where the relative relaxation time of the polymer is much shorter than the characteristic diffusion time of water transport which is controlled by concentration ...
8
Formulation and Evaluation of Hydrogel Based Oral Controlled Release Tablets of Simvastatin
... The in-vitro dissolution profile of the designed formulations of controlled release tablets was carried out using USP type II apparatus under conditions specified (temp 37± 0.5°C, 75rpm). Tablets ...
6
The preparation and evaluation of extrudates as oral controlled release dosage systems
... Only the essentially water-soluble coating additives, such as polyethylene glycols 4000, methylcellulose 400 cps, and hydroxypropyl methyl cellulose (Methocei KlOO M, Colorcon) were investigated since they proved to be ...
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RECENT TRENDS IN CONTROLLED RELEASE ORAL DRUG DELIVERY SYSTEMS: A COMPREHENSIVE REVIEW
... of oral sustained - controlled release formulations is one of the attempt to release the drug slowly into the GIT and maintain the effective drug concentration in the systemic ...
7
ORAL CONTROLLED RELEASE DRUG DELIVERY SYSTEM: AN OVERVIEW
... provide controlled drug release, although insoluble polymers can been ...drug release, it may be necessary to incorporate soluble ingredients such as lactose into ...the formulations helps to ...
7
Oral Controlled Release Drug Delivery System: A Promising Approach for the Treatment of Ulcerative Colitis
... challenges oral controlled drug delivery system seem to be a promising approach for colon ...of oral controlled drug delivery systems in ulcerative colitis for appropriate targeting of drug ...
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FABRICATION AND EVALUATION OF ORAL CONTROLLED RELEASE OF MUCOADHESIVE ALGINATE MICROBEADS CONTAINING FLUVASTATIN SODIUM
... On observation of micromeritic studies of alginate microbeads appeared as white, nearly spherical shape like and free-flowing of fluvastatin sodium microbeads were produced using the emulsification internal gelation ...
12
FORMULATION AND COMPARITIVE OPTIMIZATION OF MULTIPLE LIPID DRUG CARRIERS OF VALSARTAN FOR ORAL CONTROLLED RELEASE
... In-Vitro Drug Release Studies: The release of valsartan from niosomal formulations was determined by using membrane diffusion technique. The niosomal formulation equivalent to 40 mg of valsartan was ...
9
DEVELPOMENT AND EVALUATION OF SUSTAINED RELEASE FORMULATIONS OF VENLAFAXINE HYDROCHLORIDE
... single oral dosage form, have lead to the development of a more specialized group of oral dosage forms (modified release drug products) 3 ...to release the active drug from the product at a ...
10
An In Vitro Evaluation of Mangifera Indica Gum as a Potential Excipient for Oral Controlled-Release Matrix Tablet.
... Lornoxicam, also known as chlortenoxicam 8 , is a member of the oxicam group of nonsteroidal anti- inflammatory drugs (NSAIDs) with extremely potent anti-inflammatory and analgesic activities. Lornoxicam is commercially ...
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NANOTECHNOLOGY BASED ORAL FORMULATIONS OF TOLBUTAMIDE BY USING BIODEGRADABLE POLYMER
... The analysis by Scanning Electron Microscopy concluded that the prepared nanoparticles were almost spherical nanosized particles. Some pores were visible on the surface which may be attributed to the impressions of the ...
7
Oral controlled release drug delivery system and Characterization of oral tablets; A review
... profile. Oral drug delivery system can be categorized into (1) targeted release formulations (2) sustained release formulations and (3) immediate release ...immediate ...
10
STABILITY STUDIES OF THE OPTIMIZED ORAL CONTROLLED RELEASE VERAPAMIL HYDROCHLORIDE TABLET FORMULATIONS
... on Oral Verapamil Hydrochloride control release tablet in order to assess the physical and chemical stability of Verapamil Hydrochloride ...the formulations were tested for disintegration test, % ...
7
Design and Evaluation of Controlled Release Formulations of Ibuprofen Tablet.
... A tablet is a mixture of active substances and excipients, usually in powder form, pressed or compacted into a solid. The excipient include binders, glidants (Flow aids) and lubricants to ensure efficient tableting ...
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Controlled release tablet formulations of carvedilol
... formulating controlled release (CR) oral matrix tablet formulations of Carvedilol (CAR), an antihypertensive using cellulose ether polymer, Hydroxy Propyl Methyl Cellulose (HPMC K4M, HPMC ...
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