pancreatic beta cell
Suppression of pancreatic beta cell apoptosis by Danzhi Jiangtang capsule contributes to the attenuation of type 1 diabetes in rats
... improve pancreatic beta cell function in elderly dia- betic patients ...atic beta cell apoptosis in STZ induced type 1 diabetic rats and the possible mechanisms ...
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Regulatory effects of glucose on the catalytic activity and cellular content of glucokinase in the pancreatic beta cell Study using cultured rat islets
... Glucose regulates the cellular content of glucokinase in the pancreatic beta cell by altering the level of the enzyme. We investigated the existence of a second regulatory pathway, an alteration in ...
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Glucose and aging control the quiescence period that follows pancreatic beta cell replication
... Pancreatic beta cell proliferation has emerged as the principal mechanism for homeostatic maintenance of beta cell mass during adult ...of beta cell replication and ...
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The effect of cholesteryl ester transfer protein on pancreatic beta cell dysfunction in mice
... and beta cell lipid accumulation, we used aP2-CETPTg mouse to explore the effects of CETP on mouse pancreatic beta cell lipid composition and beta cell ...
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American ginseng modulates pancreatic beta cell activities
... protects beta cells from apoptosis A gradual loss of beta cells due to apoptosis ...grammed cell death) significantly hinders insulin produc- tion and inhibits cell ...The cell breaks ...
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Cell therapies for pancreatic beta-cell replenishment
... endocrine pancreatic lineage and insulin producing cells in vivo ...produce beta-like cells, hypothesizing that the pancreatic origin would ease the induction ...
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Original Article MiR-34a and miR-34c are involved in the pathogenesis of type-2 diabetes by modulating the cell cycle of pancreatic beta-cell
... The number of patients suffered from diabetes is continuously increasing all over the world and among the peoples with diabetes, more than 90% have type 2 diabetes (T2DM). T2DM is characterized by insulin resistance and ...
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Laser acupuncture at BL20 Point Stimulate Pancreatic Beta cell in type 1 diabetes mellitus
... Laser acupuncture at BL20 point in type 1 diabetes mellitus could increase beta cell percentage and Langerhans area, and reduce fasting blood glucose level. This study still not can exactly prove the origin ...
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Therapeutic concentrations of antidepressants inhibit pancreatic beta cell function via mitochondrial complex inhibition
... production. Pancreatic β-cells are characterized by a relatively weak expression of superoxide dismutase, catalase and glutathione peroxidase (Grankvist et ...
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Early peroxisome proliferator-activated receptor gamma regulated genes involved in expansion of pancreatic beta cell mass
... to cell proliferation and survi- val ...in cell cycle progression, new data has revealed an emerging role of D-type cyclins in transcriptional regulation and cellular differ- entiation ...b- cell ...
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Glucose Intolerance in Uremia: QUANTIFICATION OF PANCREATIC BETA CELL SENSITIVITY TO GLUCOSE AND TISSUE SENSITIVITY TO INSULIN
... TABLE IV Glucose Metabolism M, Plasma Insulin Concentration, Insulin Sensitivity, and MCR during the Euglycemic Clamp Pre- and Postdialysis Plasma insulin conc... providing a measure of [r] ...
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Involvement of the autonomic nervous system in the in vivo memory to glucose of pancreatic beta cell in rats
... the beta cell to glucose, insulin release in response to glucose was measured in HG and control rats, either under subdiaphragmatic vagotomy or after administration of the alpha ...
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Impaired pancreatic beta cell function in the fetal GK rat Impact of diabetic inheritance
... b cell mass has been investigated in the this study by performing crossing ex- periments between diabetic GK and normoglycemic W ...their pancreatic insulin content and b cell mass, albeit slightly ...
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Lipophilicity predicts the ability of nonsulphonylurea drugs to block pancreatic beta cell KATP channels and stimulate insulin secretion: statins as a test case
... mouse pancreatic islets at the 2 concentrations tested (100 nmol/L and 1 μmol/L; Figure ...whole- cell records, ...In cell- attached patches, ...
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<p>Serum CTRP3 Levels In Obese Children: A Potential Protective Adipokine Of Obesity, Insulin Sensitivity And Pancreatic β Cell Function</p>
... density lipoprotein cholesterol (HDL-C), low density lipo- protein cholesterol (LDL-C) and high sensitive C reaction protein (hsCRP) were performed by the Clinical Laboratory of the Children ’ s Hospital of Soochow ...
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Protection of silver nanoparticles using <em>Eysenhardtia polystachya</em> in peroxide-induced pancreatic β-Cell damage and their antidiabetic properties in zebrafish
... suggesting pancreatic β -cell dam- age in this group, while EP/AgNPs at a dose of 100 µ g/mL resulted in decreased plasma insulin levels (by 54%) com- pared with the glucose-induced diabetic fish group, ...
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<p>Obstructive Sleep Apnea Exacerbates Glucose Dysmetabolism and Pancreatic β-Cell Dysfunction in Overweight and Obese Nondiabetic Young Adults</p>
... or pancreatic diseases, alcohol abuse, malignancies, pregnancy, hypoxemic lung diseases, acute and/or chronic infections, autoimmune dis- eases, and current treatment with anti – in fl ammatory drugs (such as ...
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Effect of protein glycation by methylglyoxal on pancreatic beta cell function
... the cell dysfunction observed in diabetes (Shinohara, et ...a cell permeable fusion protein construct of Glo1 has been shown to prevent the beta cell ablation induced by Streptozotocin ...
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Taurine regulates insulin release from pancreatic beta cell lines
... Culture. Pancreatic b -cell lines Hit-T15 from Syrian hamster (CRL-1777; ATCC, Manassas VA) or Rin-m (CRL-2057; ATCC) were used for these ...two cell lines arises from the bio- chemical differences ...
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Glucose sensing in the pancreatic beta cell: a computational systems analysis
... The first detailed β-cell model was developed by Magnus and Keizer [28-30]. However, several mechanisms used for simulations in this model have recently been reevaluated. For example, steady-state electron ...
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