Pediatric Brain Tumors
Immunotherapy for pediatric brain tumors
... solid tumors, has shown less benefit against pediatric brain ...most pediatric brain tumors are immunologically quiescent, stemming from a low mutational ...of pediatric ...
16
A novel and generalizable organotypic slice platform to evaluate stem cell potential for targeting pediatric brain tumors
... Brain tumors are now the leading cause of cancer-related deaths in children under age ...the brain cancer ...targeting pediatric brain tumors is proposed to fill the gap in the ...
11
Treatment of Pediatric Brain Tumors in Brazzaville (Congo) about a Case Series
... Also, pediatric brain tumors sur- vivors at 5 years have an increased endocrine disease, psychiatric disorders, cog- nitive and developmental disorders [18] ...developing brain caused by the ...
9
Serial MR diffusion to predict treatment response in high grade pediatric brain tumors: a comparison of regional and voxel based diffusion change metrics
... There are several limitations of the current study. We only studied a small and heterogeneous sample size, a common problem in single-center pediatric studies that reflects the relative low incidence of ...
9
Molecular analysis of pediatric brain tumors identifies microRNAs in pilocytic astrocytomas that target the MAPK and NF-κB pathways
... slow-growing tumors that usually occur in the cerebellum or in the midline along the hypothalamic/optic ...normal brain tissue and a selection of other pediatric brain ...
13
Contrast Leakage Patterns from Dynamic Susceptibility Contrast Perfusion MRI in the Grading of Primary Pediatric Brain Tumors
... low-grade pediatric brain tumors is not known but is also likely related to the balance between T1-shortening and T2* effects of paramagnetic contrast me- dium that has leaked into the extravascular ...
8
Multiparametric Analysis of Permeability and ADC Histogram Metrics for Classification of Pediatric Brain Tumors by Tumor Grade
... histogram skewness and kurtosis did not show the same signifi- cant differences. Although the number of ADC histograms with bimodal peaks was too small for statistical analysis (6 for FL_ ADC_mean and 4 for PG_ADC_mean), ...
6
Quantitative Short Echo Time 1H MR Spectroscopy of Untreated Pediatric Brain Tumors: Preoperative Diagnosis and Characterization
... tensity, though only in arbitrary institutional units, is of po- tential importance. The lipid signal intensity is believed to originate from mobile lipid molecules as a result of tissue deg- radation and necrosis. In ...
13
Manganese-containing Prussian blue nanoparticles for imaging of pediatric brain tumors
... the brain between one hour and 3 hours, with the fluorescent signal reaching a maxi- mum at one hour (Figure ...mouse brain (without nanoparticle ...the brain stained by hematoxylin and eosin ...
15
Growth Failure After Treatment of Pediatric Brain Tumors
... GH deficiency received radiation localized to the tumor area rather than to the whole brain, resulting in a lower radiation dose to the hypothalamic–pitu- itary area. However, the small numbers in the study did ...
8
Arterial Spin Labeled Perfusion of Pediatric Brain Tumors
... pseudocontinuous labeling period of 1500 ms, followed by a 1500-ms postlabel delay. Whole-brain images were obtained with a 3D background-suppressed FSE stack-of-spirals method, with a TR of approximately 5 ...
7
The Neuroimaging Center of the Pediatric Brain Tumor Consortium–Collaborative Neuroimaging in Pediatric Brain Tumor Research: A Work in Progress
... (NCI)-funded Pediatric Brain Tumor Consortium (PBTC), the Neuroimaging Center (NIC) is dedicated to infusing the study of pediatric brain tumors with imaging “best practice” by ...
5
Choroid Plexus Neoplasms: Toward a Distinction between Carcinoma and Papilloma Using Arterial Spin Labeling
... We measured a higher rCBF with ASL in carcinomas, therefore allowing differentiation between choroid plexus carcinomas and papillomas. ASL rCBF values were very reproducible between the 2 observers. We could find a ...
5
Microrna expression signatures predict patient progression and disease outcome in pediatric embryonal central nervous system neoplasms
... embryonal tumors group and in the MB group ...in pediatric brain tumors including medulloblastomas [23], ependymomas [48] pilocytic astrocytomas [28] and in low- and high-grade astrocytomas ...
18
MethPed: a DNA methylation classifier tool for the identification of pediatric brain tumor subtypes
... with pediatric tumors with dif- fering biological behavior or responsiveness to specific therapies is urgently ...classify pediatric brain tumors into clinically relevant ...common ...
9
Proton MR spectroscopy of pediatric cerebellar tumors
... human brain tumors have been an active area of research (3– ...43). Pediatric brain tumors are distinct from those of adults, and many different tumor types are encoun- tered in ...
13
Citrate in Pediatric CNS Tumors?
... The causes for a possible accumulation of citrate in subgroups of pediatric brain tumors, either metabolic or physiologic or both, and its decline in progressing brain stem glioma are un- ...
6
A Clinicopathological Profile of Pediatric Liver Tumors
... Frederic et al. reported 29 cases of malignant hepatic tumor, in which AFP level range from 340ng/ml to 5,30,000 ng/ml and it was normal in three of cases. All patients cured had normal values of AFP with in ...
53
Malignant Tumors of Heart: A Review
... Adjuvant and neoadjuvant chemotherapy has been used at various centres to improve the poor results with resection alone. Rhabdomyosarcomas may have a better outcome with chemotherapy. Radiation has been used rarely, and ...
9
Detection and Classification of Brain Tumors
... Magnetic resonance imaging (MRI) is an advanced medical imaging technique that has proven to be an effective tool in the study of the human brain [3]. The rich information that MR images provide about the soft ...
6