Per protocol
Bounding the per protocol effect in randomized trials: an application to colorectal cancer screening
... the per-protocol effect among the 55–64-year age ...the per-protocol risk difference and risk ratio estimated under each set of assumptions are shown in ...
11
Adherence adjustment in the Coronary Drug Project: A call for better per-protocol effect estimates in randomized trials
... the per-protocol effect than in the intention-to-treat effect when making treatment ...from protocol, including lack of adherence to the assigned interventions and loss to ...conducted ...
111
Interval cohort designs and bias in the estimation of per protocol effects: a simulation study
... the per-protocol effect diverged from the null; inverse probability weighted estimates of the per-protocol 5-year risk ratio based on yearly measurement were ...
9
Per protocol analysis of therapeutic efficacy of chloroquine for the treatment of Plasmodium vivax malaria in children
... count per 100 red blood ...given per oral primaquine ...as per the WHO protocol shown in Table 1, or more frequently if ...WHO protocol, day 21 follow up was excluded due to logistic ...
5
Survival with nal-IRI (liposomal irinotecan) plus 5-fluorouracil and leucovorin versus 5-fluorouracil and leucovorin in per-protocol and non-per-protocol populations of NAPOLI-1: Expanded analysis of a global phase 3 trial.
... Treatment groups were compared for OS using an unstratified log-rank test. Only patients enrolled in the 5-FU/LV arm after a study protocol amendment to include a nal-IRIþ5-FU/LV arm were included in this ...
8
SLBN: A Scalable Max-min Fair Algorithm for Rate-Based Explicit Congestion Control
... variables per link) and only incur a constant amount of computation per protocol packet, independently of the number of sessions that cross the ...the protocol is conservative when assigning ...
9
Glutamine supplementation in cystic fibrosis: a randomized placebo controlled trial
... Analysis of changes in measurements used student's t-tests and Wilcoxon rank sum tests as appropriate. The intention to treat analysis replaced any missing values with baseline values as part of the statistical analysis ...
12
Effect of Pimobendan in Dogs with Preclinical Myxomatous Mitral Valve Disease and Cardiomegaly: The EPIC Study - A Randomized Clinical Trial
... the per-protocol (PP) primary end- point analysis if an attending veterinarian deemed it necessary to chronically administer open-label cardiovascular medication(s) for an indication other than having ...
15
Growing risk avoidance in Asian oncology site selection: how trends in site selection are limiting growth of the Asia cancer trial landscape
... Rather than a steady increase in the site pool over time, the individual data points from both the total naïve sites activated per year and naïve sites per protocol suggest that new site activation ...
9
1740774518806311.pdf
... the per-protocol effect as well as the ITT effects to a specified target ...generalized per-protocol analy- ses to complement conventional ITT comparisons, even though in this case study there ...
11
A theory based online health behaviour intervention for new university students (U@Uni:LifeGuide): results from a repeat randomized controlled trial
... There are several potential reasons for the relatively weak effects obtained in the repeat trial (which also re- late to the original trial). First, the intervention sought to target four health behaviours in a single ...
15
Real-world utilization patterns and outcomes of colesevelam hcl in the ge electronic medical record
... their last relevant follow-up A1C measurement. These patients might be considered analogous to patients in a trial analyzed as “on treatment”, “complete cases”, or “per protocol” (referred to as “on ...
8
A theory-based online health behaviour intervention for new university students (U@Uni: LifeGuide): Results from a repeat randomized controlled trial
... There are several potential reasons for the relatively weak effects obtained in the repeat trial (which also re- late to the original trial). First, the intervention sought to target four health behaviours in a single ...
15
A national survey on radiation dose in CT in The Netherlands
... patient per protocol, including the dose length product (DLP) from the scanner dose ...each protocol and available scanner were considered. Effective dose (E) per protocol was estimated ...
8
A theory-based online health behaviour intervention for new university students (U@Uni:LifeGuide): Results from a repeat randomized controlled trial
... There are several potential reasons for the relatively weak effects obtained in the repeat trial (which also re- late to the original trial). First, the intervention sought to target four health behaviours in a single ...
15
Leeds Let’s Get Active: Final Report, August 2015
... IPAQ Per-Protocol Adopters, Table 6 shows the time period between baseline and follow-up data ...IPAQ Per-Protocol participants completing follow up measures at least 6 months after signing ...
40
Lessons learnt during a complex, multicentre cluster randomised controlled trial: the ProAct65+ trial
... Each peer mentor in the trial mentored a mean of three participants (range, 1-13) in London, and a mean of three participants (range, 1-5) in Nottinghamshire/Derbyshire. Overall, both sites therefore fell short of the ...
11
Update on the transfusion in gastrointestinal bleeding (TRIGGER) trial: statistical analysis plan for a cluster randomised feasibility trial
... Methods and design: The Transfusion in Gastrointestinal Bleeding (TRIGGER) trial is a pragmatic cluster-randomised feasibility trial which aims to evaluate the feasibility of implementing a restrictive vs. liberal RBC ...
6
Intensified Antituberculosis Therapy in Adults with Tuberculous Meningitis
... A Cox regression analysis (Table S5 in the Supplementary Appendix) identified the follow- ing factors as predictors of poor survival: more severe neurologic compromise at treatment ini- tiation, as indicated by a higher ...
11
A Novel Energy Efficient Hierarchical Multi Level Cluster Routing Protocol based on LEACH
... proposed protocol, the CHs rotate among all nodes at each level, so the energy- intensive tasks such as long range transmissions are distributed among all ...
9