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Performance Liquid Chromatography-Mass Spectrometry

Biotransformation of ginsenosides Rb1, Rg3 and Rh2 in rat gastrointestinal tracts

Biotransformation of ginsenosides Rb1, Rg3 and Rh2 in rat gastrointestinal tracts

... High performance liquid chromatography (HPLC) is a powerful chemical analysis technology that allows com- plex mixtures to be transformed into separated compo- ...nents. Mass ...

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BIOANALYTICAL METHOD DEVELOPMENT, VALIDATION AND QUANTIFICATION OF METAXALONE BY LIQUID CHROMATOGRAPHY TANDEM MASS SPECTROMETRY IN RAT PLASMANallakumar P*and Siva Kumar RDOWNLOAD/VIEW

BIOANALYTICAL METHOD DEVELOPMENT, VALIDATION AND QUANTIFICATION OF METAXALONE BY LIQUID CHROMATOGRAPHY TANDEM MASS SPECTROMETRY IN RAT PLASMANallakumar P*and Siva Kumar RDOWNLOAD/VIEW

... high-performance liquid chromatographic (LCMSMS) method with mass detection was developed and validated for the rapid quantiication of metaxalone (CAS Registry No, 1665-48- 1) in rat plasma ...

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Discrimination of Radix Polygoni Multiflori from different geographical areas by UPLC-QTOF/MS combined with chemometrics

Discrimination of Radix Polygoni Multiflori from different geographical areas by UPLC-QTOF/MS combined with chemometrics

... thin-layer chromatography (TLC) scanning and high-performance liquid chromatography (HPLC) [11, 12]; the quality of various commercial speci- fications of RPM and its dregs was evaluated by ...

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Rapid and Reproducible Dibutylation Derivatization Coupled with Ultra High Performance Liquid Chromatography Tandem Mass Spectrometry for the Simultaneous Determination of Dopamine, Norepinephrine and 5 Hydroxytryptamine in Rat Brain Microdialysates

Rapid and Reproducible Dibutylation Derivatization Coupled with Ultra High Performance Liquid Chromatography Tandem Mass Spectrometry for the Simultaneous Determination of Dopamine, Norepinephrine and 5 Hydroxytryptamine in Rat Brain Microdialysates

... Chemical derivatization of the MANTs was widely applied to improve the LC-MS/MS detection, primarily through a reaction targeting the amine group and/or phenol-hydroxyl groups. The derivatization reagents utilized in ...

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Development of novel methodologies for using ICP MS in bioanalysis and drug metabolism

Development of novel methodologies for using ICP MS in bioanalysis and drug metabolism

... plasma mass spectrometry (ICP-MS) has been used as an analytical technique since the 1980’s [2, 14], but the use of the instrument in combination with high performance liquid ...

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Simultaneous determination of three major bioactive saponins of Panax notoginseng using liquid chromatography-tandem mass spectrometry and a pharmacokinetic study

Simultaneous determination of three major bioactive saponins of Panax notoginseng using liquid chromatography-tandem mass spectrometry and a pharmacokinetic study

... thin-layer chromatography [7,8], high-performance liquid chromatography (HPLC) with UV detection [9,10], fluor- escence detection [11], gas chromatography-mass spec- trometry ...

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HPLC and LCMS – A review and a recent update

HPLC and LCMS – A review and a recent update

... The chromatography term is derived from the greek words namely chroma (colour) and graphein (to ...The chromatography is very popular technique and it is mostly used ...Paper Chromatography, Gas ...

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Simultaneous Method for Quantification of Genotoxic Impurity in the Gemcitabine Hydrochloride by RP-HPLC

Simultaneous Method for Quantification of Genotoxic Impurity in the Gemcitabine Hydrochloride by RP-HPLC

... GCH (HCl): Gemcitabine; CYS: Cytosine; RP HPLC: Reverse phase liquid Chromatography; UPLC: Ultra performance liquid chromatog- raphy; MS: Mass Spectrometry; LOD: limit of det[r] ...

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Simultaneous determination of rhamnose, xylitol, arabitol, fructose, glucose, inositol, sucrose, maltose in jujube (Zizyphus jujube Mill.) extract: comparison of HPLC–ELSD, LC–ESI–MS/MS and GC–MS

Simultaneous determination of rhamnose, xylitol, arabitol, fructose, glucose, inositol, sucrose, maltose in jujube (Zizyphus jujube Mill.) extract: comparison of HPLC–ELSD, LC–ESI–MS/MS and GC–MS

... stable performance in quantitative analysis, Liquid chromatography coupled to various detectors was the most popular analytical method for determination of small molecular carbohydrates ...of ...

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Occurrence of Antimicrobials in River Water Samples from Rural Region of the State of Rio de Janeiro, Brazil

Occurrence of Antimicrobials in River Water Samples from Rural Region of the State of Rio de Janeiro, Brazil

... high-performance liquid chromatography coupled to tandem mass spectrometry and the aim of this study was to determine residues of sulfonamides and tetracyclines based on the USEPA me- ...

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A Simple HPLC-MS/MS Method for Quantification of Naltrexone and 6-beta Naltrexol: An Application to Effect of Uremic Toxins on Metabolic Reduction

A Simple HPLC-MS/MS Method for Quantification of Naltrexone and 6-beta Naltrexol: An Application to Effect of Uremic Toxins on Metabolic Reduction

... high-performance liquid chromatography–tandem mass spectrometry method for determination and quantification of naltrexone and its reduced metabolite (6-beta naltrexol); 2) assess the ...

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Analysis for petroleum products in marine environments

Analysis for petroleum products in marine environments

... For example, techniques such as high-performance liquid chromatography (HPLC), in conjunction with on-line fluorometric assay techniques and mass spectrometry, make possible the analy[r] ...

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Simultaneous measurement of multiple organic tracers in fine aerosols from biomass burning and fungal spores by HPLC MS/MS

Simultaneous measurement of multiple organic tracers in fine aerosols from biomass burning and fungal spores by HPLC MS/MS

... Three monosaccharide anhydrides (MAs: levoglucosan, mannosan, and galactosan) and sugar alcohols (arabitol and mannitol) are widely used as organic tracers for source identi fi cation of aerosols emitted from biomass ...

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A Sensitive, Stability indicating UPLC method for the identification and characterization of forced degradation products for Drometrizole Trisiloxane through MSn studies

A Sensitive, Stability indicating UPLC method for the identification and characterization of forced degradation products for Drometrizole Trisiloxane through MSn studies

... ultra performance liquid chromatography combined with tandem mass spectrometry method was developed and validated for separation, recognition, and characterization of forced degradation ...

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Journal of Applied Pharmaceutical Science

Journal of Applied Pharmaceutical Science

... ultra-performance liquid chromatography/positive ion electrospray tandem mass spectrometric method was developed and validated for the quantification of captopril in human ...- ...

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High performance liquid chromatography tandem mass spectrometry dual extraction method for identification of green tea catechin metabolites excreted in human urine

High performance liquid chromatography tandem mass spectrometry dual extraction method for identification of green tea catechin metabolites excreted in human urine

... High performance liquid chromatography tandem mass spectrometry dual extraction method for identification of green tea catechin metabolites excreted in human ...of Chromatography ...

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Application of the broadband collision-induced dissociation (bbCID) mass spectrometry approach for protein glycosylation and phosphorylation analysis

Application of the broadband collision-induced dissociation (bbCID) mass spectrometry approach for protein glycosylation and phosphorylation analysis

... Ultra-high-performance liquid chromatography (uHPLC) was performed using an Ultimate 3000 series rapid separation liquid chromatography (RSLC) system (Thermo Fisher, Hemel Hempstead, ...

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Simultaneous untargeted and targeted metabolomics profiling of underivatized primary metabolites in sulfur-deficient barley by ultra-high performance liquid chromatography-quadrupole/time-of-flight mass spectrometry

Simultaneous untargeted and targeted metabolomics profiling of underivatized primary metabolites in sulfur-deficient barley by ultra-high performance liquid chromatography-quadrupole/time-of-flight mass spectrometry

... The two discriminant positive mode molecular features (3.44_612.1519n and 3.47_612.1522n) found in leaves and roots samples respectively, were identified as the sul- fur metabolite glutathione oxidized (GSSG; see S-Plots ...

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Development and Validation of Extraction Method for the Determination of UC781 in Cervicovaginal Fluid

Development and Validation of Extraction Method for the Determination of UC781 in Cervicovaginal Fluid

... Liquid chromatography plays the important and critical role in the field of clinical pharmacology of evaluating drugs in biological ...high performance liquid chromatography with ...

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Original Article Effects of Evodiae Fructus on targeted distribution of berberine in rats

Original Article Effects of Evodiae Fructus on targeted distribution of berberine in rats

... ultra-performance liquid-chromatography tandem mass spectrometry (UPLC-MS/MS) and the target parameters including relative targeting efficiency (RTE), relative uptake efficiency (RUE) ...

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