Pituitary Adenomas
Hemorrhagic pituitary adenomas of adolescence
... a pituitary adenoma (Fig 1C). The hemorrhagic pituitary adenomas were pro- lactinomas in four patients, plurihormonal (pro- lactin/FSH) tumor in one patient, and nonfunc- tioning in one patient with ...
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Heterogeneity analysis of the proteomes in clinically nonfunctional pituitary adenomas
... in pituitary adenomas ...on pituitary adenoma proteomics data was used to analyze human pituitary ad- enomas and identify a DEP profile ...stratify pituitary adenomas was based ...
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MR imaging of pituitary adenomas using a prototype resistive magnet: preliminary assessment
... As in the case of the normal pituitary gland, on IR images, most pituitary adenomas exhibited a signal intensity less than that of the pons, markedly less than clival or dorsum sellae bo[r] ...
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Microscopic Transsphenoidal Surgery for Pituitary Adenomas in Children and Adolescents
... microscopic pituitary adenomas surgery in twenty-one patients less than 20 years ...pediatric pituitary adenomas, this topic is a very relevant subject in field of ...producing adenomas ...
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Original Article Overexpression of EpCAM and Trop2 in pituitary adenomas
... Pituitary adenomas (PAs) are epithelial tumors arising from adenohypophysial cells and repre- sent 10% to 15% of primary intracranial neo- plasms ...nonfunctional Pituitary adeno- mas (NFPAs) and ...
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Original Article Immunohistochemical expression of somatostatin receptor subtypes 2 and 5 in thyrotropin-secreting pituitary adenomas: a consecutive case series of pituitary adenomas
... Somatostatin peptides bind to the SSTRs expressed on the cells of the target tissues, exerting a series of biological effects. In the central nervous system, somatostatin acts as a neuromodulator and neurotransmitter ...
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Original Article CD151 up-regulation contributes to the invasion of pituitary adenomas
... normal pituitary tissue (n=7), CD151 mRNA levels are increased in non-invasive pituitary adenomas (n=36) and further increased in invasive pituitary adeno- mas (n=24) (Figure ...normal ...
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Hemorrhage Within Pituitary Adenomas: How Often Associated with Pituitary Apoplexy Syndrome?
... To determine the clinical significance and specificity of suspected intratumoral hemorrhage in pituitary adenomas, we reviewed the clinical presentations, CT results , and findings at su[r] ...
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Original Article Expression of Eag1 K+ channel and ErbBs in human pituitary adenomas: cytoskeleton arrangement patterns in cultured cells
... tumor pituitary cells have been associated with cell transformation to an inva- sive phenotype [14-17], as is seen in other tumor cells ...in pituitary adenomas the expression of mole- cules ...
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Histological criteria for atypical pituitary adenomas – data from the German pituitary adenoma registry suggests modifications
... reports from a total of N = 4232 patients documented between 2005 and 2012 were analyzed. Therefore, 4101 tumors were diagnosed as typical pituitary adenomas (TPAs; 96.9 %) and 121 as atypical ...
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The clinical characteristics of three subgroups of non functioning pituitary adenomas
... non-functioning pituitary adenomas do not overproduce hormones, many will stain positive for a particular pituitary hormone, which can be used to differentiate these adenomas into ...
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CT of the Sella Turcica after Transsphenoidal Resection of Pituitary Adenomas
... A retrospective review of 120 patients undergoing transsphenoidal surgery for pituitary adenomas revealed that computed tomography CT was less sensitive and less specific than hormonal m[r] ...
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Phosphorylation of kinase insert domain receptor by cyclin- dependent kinase 5 at serine 229 is associated with invasive behavior and poor prognosis in prolactin pituitary adenomas
... of pituitary adenoma cells remains to be ...normal pituitary cells, associated with p35, and that CDK5 activity was upregulated in pituitary ...of pituitary cells were regulated by the CDK5 ...
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The risks of overlooking the diagnosis of secreting pituitary adenomas
... Secreting pituitary adenomas that cause acromegaly and Cushing ’ s disease, as well as prolactinomas and thyrotroph adenomas, are uncommon, usually benign, slow-growing ...Consequently, ...
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Glycoprotein hormone genes are expressed in clinically nonfunctioning pituitary adenomas
... analyzed pituitary hormone gene expression in clinically nonfunctioning pituitary adenomas using specific oligonucleotide probes for the messenger (m)RNAs encoding growth hormone, prolactin, ACTH, ...
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Analysis of whole genome-wide microRNA transcriptome profiling in invasive pituitary adenomas and non-invasive pituitary adenomas
... Background: Dysregulation of microRNAs (miRNAs) plays a critical role during the occurrence and progress of pituitary adenomas (PAs). However, the roles of miRNAs in the invasiveness of PA are poorly ...
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Differential expression of microRNAs in GH-secreting pituitary adenomas
... in pituitary tumori- genesis ...of pituitary adenomas remains largely ...GH-secreting pituitary adenomas samples and normal pituitary samples by miRCURY™ Locked Nucleic Acid ...
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CDK5 and Its Activator P35 in Normal Pituitary and in Pituitary Adenomas: Relationship to VEGF Expression
... Frozen pituitary and pituitary adenomas tissues were harvested by washing with ice-cold phos- phate-buffered saline (PBS) three times and then scraping in ice-cold RIPA buffer (50 mM Tris, pH ...
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PPAR γ receptor ligands: novel therapy for pituitary adenomas
... growing pituitary tumors, the effects of TZD treatment were tested on growth of already established pituitary gonadotroph tumors in ...gonadotroph pituitary tumor cells were injected subcutaneously ...
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Cavernous Sinus Invasion by Pituitary Adenomas
... The CT findings in these 19 patients were cavernous sinus expansion 17 patients, compression of the gasserian ganglion V, complex 14, visibly engulfed internal carotid artery 14, invasio[r] ...
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