platelet function
Platelet function in the postprandial period
... stimulates platelet aggregation [22] which might particularly interfere in MS-patients, a large ever growing part of the ...reduced platelet aggregation (ADP, collagen, epinephrine) was reported when ...
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Carbenicillin and Penicillin G Inhibit Platelet Function In Vitro by Impairing the Interaction of Agonists with the Platelet Surface
... of platelet dysfunction. These antibiotics also inhibit platelet aggregation in vitro, although several-fold larger concentrations of drug are required to demonstrate this ...impair platelet ...
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Hypothermia: effects on platelet function and hemostasis
... hemostatic function, which involves platelets, coagulation factors, plasma proteins, endothelial and other cells and flow ...of platelet activators, rather than a consequence of an intrinsic defect in ...
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Rap1b is required for normal platelet function and hemostasis in mice
... in platelet function has been ...Rap1b-null platelet function is decreased activation of integrin a IIb b 3 in response to stimulation with agonists and signaling downstream from the integrin ...
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Platelet function tests: a comparative review
... a platelet plug. Qualitative and/or quantitative platelet defects promote bleeding, whereas the high residual reactivity of platelets in patients on antiplatelet therapies moves forward thromboembolic ...of ...
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Factors affecting human platelet function in relation to atherosclerosis
... induce platelet aggregation, was in fact adenosine diphosphate ...of platelet aggregation. He made this possible by introducing the platelet aggregometer (a slightly modified Unicam ...
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Platelet function following induced hypoglycaemia in type 2 diabetes
... of platelet function using well-established ...measuring platelet function at euglycaemia and hypoglycaemia in the same clamp study, rather than in two separate studies, making it difficult ...
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Use of next-generation sequencing and candidate gene analysis to identify underlying defects in patients with inherited platelet function disorders
... targeted platelet gene analysis have allowed us to identify and prioritize candi- date gene defects that could underlie or contribute to the platelet function defects observed in the index cases ...
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Remote assessment of platelet function in patients with acute stroke or transient ischaemic attack
... on platelet function reactivity and activation. Methods. Platelet function, assessed by remotely measured surface expression of P-selectin, was assessed in patients at their time of ...that ...
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Analysis of platelet function: role of microfluidics and nanodevices
... of platelet thrombus ...of platelet aggregation have been obtained by studying this phenomenon under static or quasi-dynamic conditions at the macroscale ...studying platelet function in ...
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In Vitro impairment of whole blood coagulation and platelet function by hypertonic saline hydroxyethyl starch
... The mechanism of action of HH to improve blood pressure is based on mobilization of extravasal fluids along an osmotic gradient by intavasal administration of HH [20]. We suspected this intavasal hyperosmolarity also to ...
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Plasmin inhibition of platelet function and of arachidonic acid metabolism
... affect platelet shape change, release, or aggregation (less than ...of platelet aggregation in response to thrombin, ionophore A23187, and ...from platelet membrane phospholipids and the ...
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Assessment of platelet function in patients with stroke using multiple electrode platelet aggregometry: a prospective observational study
... Limitations: this is a small single centre study and hence may not be generalizable to other populations. Aspirin and clopidogrel intake at baseline was self- reported by patients or their family. Although MEA results ...
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Evolving role of platelet function testing in coronary artery interventions
... The variable response to antiplatelet agents is well- known and has garnered more attention after several “boxed warnings” on clopidogrel. Three sequential boxed warnings on clopidogrel have led to intense controversy. ...
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Platelet function in brown bear (Ursus arctos) compared to man
... of platelet function in order to characterize what specific part of aggregation is inhibited in ...of platelet function that is not generalizable to other times of the year - ...inhibit ...
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Evaluation of platelet function in horses undergoing colic surgery using the PFA 100 platelet function analyser
... reduced platelet count, accompanied by lower mean platelet volume in the surgically treated horses, occurs concomitantly with a prolonged closure time ...(Platelet Function Analyzer-100) using ...
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Inhibition of platelet function by recombinant soluble ecto ADPase/CD39
... collagen-induced platelet activation (21) and binds ir- reversibly with ATPDases found on several cell types (22, ...of platelet activation by ADP ...
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Endogenous prostacyclin biosynthesis and platelet function during selective inhibition of thromboxane synthase in man
... in platelet-rich plasma as well as both aggregation and nucleotide release induced by collagen (95 micrograms/ml) in platelet-rich plasma and whole blood were unaltered by ...a platelet-inhibitory ...
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Enhancement of platelet function by superoxide anion
... As shown in Table I, the addition of washed platelets to KRP buffer that contained 0.15 mM xanthine and 150 ,ug/ml xanthine oxidase caused them to release [14C]serotonin.. Induction of t[r] ...
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Evaluation of the TEG® platelet mapping™ assay in blood donors
... platelet function analyzer 100 (PFA-100), likely the most widely used point of care test for platelet inhibition, meas- ures the time required for blood under simulated high shear flow to occlude a ...
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