Predictors of Response
Genomic and epigenomic predictors of response to guadecitabine in relapsed/refractory acute myelogenous leukemia
... genomic predictors of response to guadecitabine for r/r AML patients, we investigated hematopoietic cell samples from the patients enrolled in phase I/II trials of guadeci- tabine for their DNA methylation ...
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Predictors of response to methotrexate in juvenile idiopathic arthritis
... clinical response to MTX among the patients, while there does not appear to be any advantages related to efficacy or safety with either the oral or parenteral method of administration although it is believed by ...
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Efficacy and Safety of Infliximab Therapy and Predictors of Response in Korean Patients with Crohn's Disease: A Nationwide, Multicenter Study
... In conclusion, we have demonstrated the efficacy of inflix- imab in induction and maintenance treatments in Korean pa- tients with luminal and fistulizing CD. Infliximab treatment was safe and well tolerated. However, ...
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Predictors of response to fixed-dose vasopressin in adult patients with septic shock
... hemodynamic response and deter- mine factors associated with response to AVP in a large cohort of adult patients with septic ...of response to AVP ...
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Clinical and quantitative computed tomography predictors of response to endobronchial lung volume reduction therapy using coils
... Objectives: Bronchoscopic lung volume reduction using coils (LVRC) is a well-known treatment option for severe emphysema. The purpose of this study was to identify quantitative computed tomography (QCT) and clinical ...
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Predictors of response and drug survival in ankylosing spondylitis patients treated with infliximab
... are predictors of patients’ clinical response to anti-TNFα treatment and could be useful when pa- tients with a negative response are being evaluated for ...
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Symptom predictors of response to electroconvulsive therapy in older patients with treatment-resistant depression
... A medical history and physical examination, together with routine blood and urine investigations, an electrocardiogram, a cerebral computed tomography scan, and a chest film were used to screen for general medical ...
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Structural predictors of response to intra articular steroid injection in symptomatic knee osteoarthritis
... Intra-articular steroid injection (IASI) is an effective [1], widely used [2] and recommended treatment [3] for individuals with symptomatic osteoarthritis (OA) of the knee with short term pain relief lasting up to 3–4 ...
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Predictors of long-term response to abiraterone in patients with metastastic castration-resistant prostate cancer: a retrospective cohort study
... potential predictors of response [1–3], at present there are no validated predictive biomarkers able to inform clinicians on best treatment selection for mCRPC patients ...
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Cost saving and predictive factors of response to rituximab in rheumatoid arthritis, including the IL-6 promoter gene polymorphism
... carrying predictors and patients without ...of predictors of response to rituximab may account for a greater cost saving, and for a possible cost/QALY below the threshold of € 50 000 in RA ...of ...
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Attribution in the presence of a long-memory climate response
... dynamic response to ...memory response. The response function to all forcing com- ponents is assumed to have the same shape and involves dis- tortion, not just shifts, of the forcing ...dynamic ...
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Neutrophil lymphocyte ratio and duration of prior anti-angiogenic therapy as biomarkers in metastatic RCC receiving immune checkpoint inhibitor therapy
... immune response by blocking PD-1 and PD L1 inter- action ...overall response rate (ORR) of 27% and progression-free survival (PFS) 56% at 24 weeks ...
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Measures of bronchodilator response of FEV<sub>1</sub>, FVC and SVC in a Swedish general population sample aged 50–64 years, the SCAPIS Pilot Study
... In our regression models including the total population, the factors that were significantly associated with flow responding (% Δ FEV 1 ) in the total population were airway obstruction, height, weight and ...
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PubMedCentral-PMC4996139.pdf
... Background . Sofosbuvir (SOF) is active against all hepatitis C virus (HCV) genotypes, and SOF-based therapies lead to high rates of sustained virologic response (SVR). However, genotype 3 (GT3) HCV remains a ...
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Monitoring Thiopurine Metabolites in Korean Pediatric Patients with Inflammatory Bowel Disease
... AZA is an inactive prodrug that is metabolized to produce the nucleotide metabolites, 6-TGN, 6-MMP, and 6-thioura- cil. Among these metabolites, 6-TGN seems to be one of the active metabolites accountable for therapeutic ...
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Assessment of the impact of adherence and other predictors during HAART on various CD4 cell responses in resource-limited settings
... the predictors identified during ART, age and baseline clinical state did not have significant influence on immunological response in terms of CD4 cell gain in the present ...cell response was the ...
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Peripheral memory and naïve T cells in non-small cell lung cancer patients with lung metastases undergoing stereotactic body radiotherapy: predictors of early tumor response
... tumor response predic- tors after ...complete response in lung metastases from various primary tumors 6 months after SBRT ...complete response, 6 months after SBRT [27, ...tumor response ...
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Pro-gastrin-releasing peptide (ProGRP) as a biomarker in small-cell lung cancer diagnosis, monitoring and evaluation of treatment response
... was more than fourfold higher than those with lower marker levels, while the relative risk of death for patients with poorer PS, no response to treatment and advanced stage of disease was 2.5-fold, 1.35-fold and ...
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Response Rates in 21st Century Organizational Survey Research: A Conceptual Model and Meta-analysis
... low response rates can limit the statistical power needed to perform analyses of interest (Rogelberg & Stanton, 2007), subsequently requiring organizations to incur greater costs in soliciting additional ...
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A prospective evaluation of cardiovascular magnetic resonance measures of dyssynchrony in the prediction of response to cardiac resynchronization therapy
... CRT response was determined from receiver-operator char- acteristic (ROC) ...of response were calculated for each measure using Poisson regression with robust standard errors to deter- mine the strength of ...
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