Primordial germ cells
Intracellular localizations of the Dead End protein in Xenopus primordial germ cells
... The Xenopus germline is specified by inheriting a special cyto- plasm, germ plasm (GP), associated with the vegetal cortex of the egg. We demonstrated that the GP was sufficient for germline specification (Tada et ...
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Compensatory proliferation of endogenous chicken primordial germ cells after elimination by busulfan treatment
... Primordial germ cells (PGCs) are the precursors of germ cells in most vertebrates and play an important role in early embryonic germ cells ...
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The problem of the origin of primordial germ cells (PGCs) in vertebrates: historical review and a possible solution
... of primordial germ cells (PGCs) in vertebrates is ...of primordial ectomesenchyme destined to give rise to a part of the mesoderm and the PGCs separates early from the part destined to give ...
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Germes is involved in translocation of germ plasm during development of Xenopus primordial germ cells
... plasm’. Germ plasm is present in the vegetal cortex of a fertilized egg, where it divides into about four blastomeres via the first two cleavages, and then distributes unequally to daughter cells until ...
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Visualization of primordial germ cells in the fertilized pelagic eggs of the barfin flounder Verasper moseri
... ABSTRACT Primordial germ cells (PGCs) appear during early embryogenesis and differentiate into gametes through oogenesis or spermatogenesis. Teleost PGCs can be visualized by injecting RNA ...
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A replication dependent passive mechanism modulates DNA demethylation in mouse primordial germ cells
... Germline cells reprogramme extensive epigenetic modifications to ensure the cellular totipotency of subsequent generations and to prevent the accumulation of ...Notably, primordial germ cells ...
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Isolation of teleost primordial germ cells using flow cytometry
... ABSTRACT Primordial germ cells (PGCs) generate gametes, the only cells that can transmit genetic information to the next ...examine germ cell migration to the gonadal ...positive ...
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Gβγ signaling controls the polarization of zebrafish primordial germ cells by regulating Rac activity
... During development, primordial germ cells (PGCs) migrate from the sites of their specification towards the region in which the future gonad develops. This cell migration requires polarization of PGCs ...
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Identification of side population cells in mouse primordial germ cells and prenatal testis
... stem cells of spermatogenesis are derived from an embryonic cell population called primordial germ cells ...stem cells displaying the “side population” (SP) phenotype have been ...
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From primordial germ cells to primordial follicles: a review and visual representation of early ovarian development in mice
... ovarian germ stem cell; OSC, ovarian stem cell; P*, postnatal day *; PGCs, primordial germ cells; PRDM1/14, positive regulatory domain zinc finger protein 1 or 14; PRMT5, arginine ...
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Spermatogenesis from epiblast and primordial germ cells following transplantation into postnatal mouse testis
... Mammalian germ cells undergo unique genetic and cellular changes as they develop and differentiate to form functional ...epiblast cells at around 6.5 days post coitum (dpc) gives rise to ...
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Differentiation of primordial germ cells from premature ovarian insufficiency-derived induced pluripotent stem cells
... stem cells, including human ESCs and iPSCs, and it initiates the human germ cell transcriptional network by work with upstream of BLIMP1 and other ...of primordial germ ...obtained ...
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Generation of germ line chimera zebrafish using primordial germ cells isolated from cultured blastomeres and cryopreserved embryoids
... ABSTRACT Primordial germ cells (PGCs) are the only cells in developing embryos with the potential to transmit genetic information to the next ...produced germ-line chimeras of cyprinid ...
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Epigenetic reprogramming in mouse pre implantation development and primordial germ cells
... AID (activation-induced deaminase) and APOBECs (apolipoprotein B mRNA editing enzyme, catalytic polypeptides) are a group of cytidine deaminases in vertebrates that can introduce mutations in DNA and RNA by deaminating ...
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Mouse primordial germ cells produce cysts that partially fragment prior to meiosis
... Murine primordial germ cells (PGCs) colonize the gonads at around embryonic day (E) ...somatic cells and cluster into nests (McLaren, 1984; Tam and Snow, 1981) ...female germ ...
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Interleukin 2 induces the proliferation of mouse primordial germ cells in vitro
... ABSTRACT Primordial germ cells (PGCs) are the stem cell precursors of the germ line. Several growth factors contribute to enlarging the PGC population by acting as mitogens, survival factors ...
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The majority of early primordial germ cells acquire pluripotency by AKT activation
... Primordial germ cells (PGCs) are undifferentiated germ cells in embryos, the fate of which is to become gametes; however, mouse PGCs can easily be reprogrammed into pluripotent ...
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Inter species transplantation and migration of primordial germ cells in cyprinid fish
... ABSTRACT Primordial germ cells (PGCs) are the only cells in developing embryos that can transmit genetic information to the next ...using germ-line ...produce germ-line chimeras ...
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Primordial germ cells: the first cell lineage or the last cells standing?
... Germ cells and somatic cells (or soma) engender perhaps the most basic division of cellular function in metazoan ...biology. Germ cells are the source of heritable genetic variation, ...
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Differentiation of mouse primordial germ cells into female or male germ cells
... Mouse primordial germ cells (PGCs) migrate from the base of the allantois to the genital ...embryonic germ (EG) cells. Observation of ectopic germ cells and studies of ...
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