Progenitor stem cells: classification and types
Haematopoietic stem and progenitor cells
... so-called transiently contributing clones have varied phenotypic characteristics, which could influence the therapeutic efficacy of ex vivo expanded cells. Continuous expansion of a heterogeneous cell population ...
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Hematopoietic Stem and Progenitor Cells
... transgenic donor mice that express a readily detectable reporter molecule, such as green fluorescent protein. 4 The frequency of repopulating HSCs in a “test” population can be measured by using a limiting-dilution ...
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hematopoietic stem/progenitor cells
... Stem/progenitor cells occur in fetal blood (1, 17), and human umbilical cord blood contains stem cells (20, 21), so called because in colony assay in vitro they exhibit replating efficie[r] ...
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mTOR signaling in stem and progenitor cells
... Treating Gsk3-deficient HSCs with rapamycin has little effect on their differentiation, but inhibition of AKT and S6K1 significantly impairs the ability of HSCs to differentiate (Guezguez et al., 2016). The loss of ...
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The characterisation of endometrial epithelial stem/progenitor cells
... epithelial cells to a greater degree than MACS sorting, therefore the cells do not seem to grow following the FACS ...the cells, for example due to the exposure to high pressures or a prolonged time ...
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Nutritional regulation of stem and progenitor cells in Drosophila
... various stem and progenitor cell compartments in Drosophila has advanced our understanding of how different organs communicate with the external environment and with each ...different types of ...
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Neural stem and progenitor cells in cancer and development
... ABSTRACT Stem cells are unique cells that possess the capacities to both self-renew and give rise to multiple differentiated ...major types of stem cells that help to create the ...
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Endothelial Stem and Progenitor Cells for Regenerative Medicine
... muscle cells [5]. The SP as a marker of stem cells was first identified by Goodell et ...marrow cells effluxing Hoechst 33342 dye through ATP-cassette transporter receptors and this subset ...
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Angiogenic potential of endothelial progenitor cells and embryonic stem cells
... that cells of a comparable phenotype and angiogenic potential to EPCs, which can be difficult to expand easily in vitro, can be efficiently derived by the differentiation of ...
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It Takes a "Village of Stem Cells and Progenitor Cells" to Build a Brain.
... transcription factor, elicits the Trx-regulated epigenetic memory to maintain neuroblast heterogeneity during fly larval brain neurogenesis. Trx and Polycomb-group (PcG) proteins frequently act antagonistically to ...
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The development and potential of spinal cord stem and progenitor cells
... ependymal cells are changed upon bOEC transplantation, we further performed qPCR to analyze the ...ependymal cells are also crucial to reinforce the spinal cord after SCI by serving as a source of ...
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Harnessing endogenous stem/progenitor cells for tendon regeneration
... desired progenitor population. Recently, the concept that endogenous stem/progenitor cells could be used for regenerating tissues has emerged as a promising approach that potentially overcomes ...
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Role of microRNAs in stem/progenitor cells and cardiovascular repair
... endothelial cells in vitro and knockdown of miR-17 and miR-20a increased vessel formation as observed in a matrigel plug assay in ...tumor cells transduced with the miR-17-92 cluster, 66 indicating that the ...
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Mapping the transcriptional landscape of haematopoietic stem and progenitor cells
... select cells of interest to reveal their expression ...dendritic cells (Kovacic et ...mast cells and basophils and its presence in a distinct branch on the SPRING plot could indicate an early point ...
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Role of microRNAs in stem/progenitor cells and cardiovascular repair
... stem cells, as well as in differentiation of cardiovascular lineage ...embryonic stem cells, thereby promoting embryonic stem cell ...cardiovascular progenitor cells, ...
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Cardiac Progenitor Cells from Stem Cells: Learning from Genetics and Biomaterials
... Cardiac Progenitor Cells (CPCs) show great potential as a cell resource for restoring cardiac function in patients affected by heart disease or heart ...generating cells of all the cardiac lineages. ...
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Transdifferentiation of human adipose-derived mesenchymal stem cells into oligodendrocyte progenitor cells
... condition at 4 °C overnight. For this purpose, anti- A2B5 FITC antibody (1 µg/ml Abcam, Cambridge, MA, USA), anti-oligodendrocyte transcription factor (Olig2) FITC antibody (1:1000; Abcam, Cambridge, MA, USA), anti- ...
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Wnt5a regulates dental follicle stem/progenitor cells of the periodontium
... follicle stem/progenitor cells to produce robust mineralization with elevated expression of Runx2, alkaline phosphatase, collagen 1 α 1 and ...follicle stem/progenitor cells or ...
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CD97 is differentially expressed on murine hematopoietic stem- and progenitor-cells
... INT cells are the only bone mar- row subpopulation with HSC characteristics, including repopulating capacity in vivo and CAFC-day 35 activity in ...colony-forming progenitor cells and CAFC-day 7 ...
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Molecular regulation of forebrain development and neural stem/progenitor cells
... of stem/progenitor cellular behavior has an important role during brain development, since virtually all the cells in brain originate from stem/progenitor ...neural ...
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