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progesterone-receptor

Metabolomic study and in silico approach of DLBS1442 as progesterone receptor agonist

Metabolomic study and in silico approach of DLBS1442 as progesterone receptor agonist

... Endometriosis prevalence has been known to be quite high among women of reproductive age and with pelvic pain and/or infertility. The reason is that the estrogen level in the eutopic endometrium of women with ...

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Association of estrogen receptor α and progesterone receptor A expression with hormonal mammary carcinogenesis: role of the host microenvironment

Association of estrogen receptor α and progesterone receptor A expression with hormonal mammary carcinogenesis: role of the host microenvironment

... estrogen receptor (ER)-positive and progesterone receptor (PR)-positive ductal invasive mammary carcinomas in BALB/c ...and progesterone, and the levels of ER and PR expression in MPA-treated ...

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Effect of long-term treatment with steroid hormones or tamoxifen on the progesterone receptor and androgen receptor in the endometrium of ovariectomized cynomolgus macaques

Effect of long-term treatment with steroid hormones or tamoxifen on the progesterone receptor and androgen receptor in the endometrium of ovariectomized cynomolgus macaques

... The progesterone receptor (PR) and androgen receptor (AR) belong to the nuclear receptor superfamily. Two isoforms of PR (A and B) have been identified with different functions. The expression ...

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Diagnostic value of progesterone receptor and p53 expression in uterine smooth muscle tumors

Diagnostic value of progesterone receptor and p53 expression in uterine smooth muscle tumors

... showed progesterone receptor expression with slight-to-moderate ...that progesterone receptors were expressed in 43% of the leiomyosarcoma cases; a per- centage which is much higher than the one ...

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Spontaneous feline mammary intraepithelial lesions as a model for human estrogen receptor- and progesterone receptor-negative breast lesions

Spontaneous feline mammary intraepithelial lesions as a model for human estrogen receptor- and progesterone receptor-negative breast lesions

... Ltd.), progesterone receptor monoclonal antibody PR 10A9 at 1: 50 dilution (Immunotech, Mar- selle, France), Ki67 monoclonal mouse anti-human anti- body clone MIB-1 at 1:50 dilution (DakoCytomation), and ...

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Progesterone receptor membrane component 1 regulates hepcidin biosynthesis

Progesterone receptor membrane component 1 regulates hepcidin biosynthesis

... epitiostanol, progesterone, and mifepristone, which decrease ferroportin levels by increasing the biosynthesis of ...pathways. Progesterone receptor membrane component-1 (PGRMC1) was required for ...

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Distinct functions and regulation of epithelial progesterone receptor in the mouse cervix, vagina, and uterus

Distinct functions and regulation of epithelial progesterone receptor in the mouse cervix, vagina, and uterus

... through progesterone receptor (PR) and estrogen receptor (ER), respectively. PR and ER are ligand−dependent transcription factors belonging to the nuclear receptor superfamily [1]. ERα and ERβ ...

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Progesterone receptor signaling in the initiation of pregnancy and preservation of a healthy uterus

Progesterone receptor signaling in the initiation of pregnancy and preservation of a healthy uterus

... the progesterone receptor It is known that classical nuclear receptor signaling involves binding ligand, dimerizing with another receptor, and binding to response elements within promoters to ...

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The pattern of β catenin responsiveness within the mammary gland is regulated by progesterone receptor

The pattern of β catenin responsiveness within the mammary gland is regulated by progesterone receptor

... Experiments involving ␤ -catenin loss- and gain-of-function in the mammary gland have decisively demonstrated the role of this protein in normal alveologenesis. However, the relationship between hormonal and ␤ -catenin ...

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Growth of a progesterone receptor-positive meningioma in a female patient with congenital adrenal hyperplasia

Growth of a progesterone receptor-positive meningioma in a female patient with congenital adrenal hyperplasia

... the progesterone receptor (varying binding affinities have been reported) ...to progesterone receptors in situations of supraphysiological levels of 17OHP in female patients with CAH has not been ...

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Dienogest increases the progesterone receptor isoform B/A ratio in patients with ovarian endometriosis

Dienogest increases the progesterone receptor isoform B/A ratio in patients with ovarian endometriosis

... major progesterone receptor (PR) iso- forms were identified, namely PR-A and PR-B ...of progesterone target genes, whereas PR-A has been shown to act as a dominant repressor of PR-B ...

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Frequency of Polymorphism Alu Insertion in Progesterone Receptor Gene in Endometriosis

Frequency of Polymorphism Alu Insertion in Progesterone Receptor Gene in Endometriosis

... Endometriosis is a common gynecological disease, which is defined as a development of endometrial tissue which is outside the uterine cavity [1]. It causes some problems such as dysmenorrheal, pelvic pain, dyspareunia, ...

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Immunohistochemical evaluation of Estrogen receptor (ER) and Progesterone Receptor (PR) in Endometrial carcinomas and its precursors

Immunohistochemical evaluation of Estrogen receptor (ER) and Progesterone Receptor (PR) in Endometrial carcinomas and its precursors

... This is to certify that this is the dissertation work entitled “Immunohistochemical evaluation of Estrogen receptor (ER) and Progesterone Receptor (PR) in Endometrial carcinomas and its precursors” ...

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Original Article The putative role of estrogen receptor and progesterone receptor on the pathogenesis of endometrial simple hyperplasia

Original Article The putative role of estrogen receptor and progesterone receptor on the pathogenesis of endometrial simple hyperplasia

... estrogen receptor (ER) and progesterone receptor (PR) play important roles in the normal cycling of endometrium; however their exact role in pathogenesis of endometrial simple hyperplasia (SH) is ...

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The effects of black cohosh on the regulation of estrogen receptor (ERα) and progesterone receptor (PR) in breast cancer cells

The effects of black cohosh on the regulation of estrogen receptor (ERα) and progesterone receptor (PR) in breast cancer cells

... Abstract: The North American plant Cimicifuga racemosa, also known as black cohosh (BC), is a herb that recently has gained attention for its hormonal effects. As the usage of hormone replacement therapy is declining due ...

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Molecular determinants of context-dependent progesterone receptor action in breast cancer

Molecular determinants of context-dependent progesterone receptor action in breast cancer

... Emerging evidence suggests that interactions between members of the SR superfamily is an additional regulatory step in determining target-gene specificity. Interactions between ER and AR have been the focus of recent in- ...

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The relationship of cerb B 2 expression with estrogen receptor and progesterone receptor and prognostic parameters in endometrial carcinomas

The relationship of cerb B 2 expression with estrogen receptor and progesterone receptor and prognostic parameters in endometrial carcinomas

... transmembrane receptor with an intracellular tyrosine kinase that plays an important role in coordinating the endometrial growth factor receptor signaling ...estrogen receptor (ER) and ...

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Estrogen receptor (ER) and progesterone receptor (PgR) in breast cancer of Indian women

Estrogen receptor (ER) and progesterone receptor (PgR) in breast cancer of Indian women

... estrogen receptor (ER) has been shown to be a prognostic factor for patients with breast cancer in ...ER receptor status is to assess predictive response to hormonal ...and progesterone ...

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Characterization and prognosis of estrogen receptor positive/progesterone receptor negative male breast cancer: a population based study

Characterization and prognosis of estrogen receptor positive/progesterone receptor negative male breast cancer: a population based study

... estrogen receptor (ER) and progesterone receptor (PR) markers has been recommended for all newly diagnosed breast cancer patients by the College of American Pathologists and American Society of ...

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Progesterone reverses the mesenchymal phenotypes of basal phenotype breast cancer cells via a membrane progesterone receptor mediated pathway

Progesterone reverses the mesenchymal phenotypes of basal phenotype breast cancer cells via a membrane progesterone receptor mediated pathway

... as progesterone (P4) in the pathogenesis of BPBC remain ...nuclear progesterone receptor (PR), trans- location of P4/PR complex into the nucleus and subse- quent activation of target genes over the ...

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