Protein interaction networks
Modularity detection in protein protein interaction networks
... biological networks, and its role in functional and structural characterization of constituent ...large networks such as Protein-Protein Interaction ...
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Comparison of Hubs in Effective Normal and Tumor Protein Interaction Networks
... constructed protein interaction networks of cancerous and normal ...These protein interaction networks are constructed using gene- expression profiles measured from different ...
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Complex tree: the basic framework of protein protein interaction networks
... into protein- protein interaction networks ...complex networks theory to analyze the protein-protein interactions from Database of Interacting Prot- ...
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Simplified Swarm Optimization Based Function Modules Detection in Protein-to-Protein Interaction Networks
... on protein interaction networks conducted in recent years, including the commonly used protein databases and traditional detection ...filtered protein number, and more stable degree of ...
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Multiple Alignment of Protein Interaction Networks by Three-Index Assignment Algorithm
... After the communities have been detected using CFinder this step maps the communities having the highest similarity score and later extracts the mapped proteins in those mapped communities. As discussed earlier, in ...
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Ontology integration to identify protein complex in protein interaction networks
... the protein interaction ...improve protein complexes ...cognate protein expression may be modest at ...of protein- protein ...the protein interac- tion ...
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Modular organization in the reductive evolution of protein protein interaction networks
... throughput protein interaction maps of ...Buchnera interaction networks was based on the assumed low rate of protein interaction turnover [16] and the weak probability that new ...
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Protein complex detection with semi-supervised learning in protein interaction networks
... detected protein com- plexes in protein-protein interaction networks from a different ...PPI networks, we proposed a semi-supervised prediction model with neural ...represent ...
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Optimizing a global alignment of protein interaction networks
... of protein interaction networks can be broadly classified into two categories: local and global ...the networks (Singh et ...PPI networks is to search for the best consistent mapping ...
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Construction and Analysis of Tissue-Specific Protein-Protein Interaction Networks in Humans
... in protein-protein interaction network of 38 different tissues of the human ...human protein-protein interaction ...different protein-protein interaction ...
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Design principles for cancer therapy guided by changes in complexity of protein-protein interaction networks
... KEGG networks are available from the KEGG web- site ...represent protein-DNA interactions we do not focus on ...the protein-protein interaction network as generated by R-script ...
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Protein-protein interaction networks: unraveling the wiring of molecular machines within the cell
... PPI networks, because the forming nodes tend to have related biological functions and many times is a good way to predict functional ...Since protein interaction networks are highly connected, ...
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Structure-based Prediction of Protein-protein Interaction Networks across Proteomes
... of protein- protein interactions is one of the central objectives of systems biology, with the goal to elucidate the role of human genes in health and in ...binary interaction between human proteins ...
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Evaluating Joint Modeling of Yeast Biology Literature and Protein Protein Interaction Networks
... articles and yeast protein-protein interaction networks. The topic coherence of the emer- gent topics and the ability of the model to re- trieve relevant scientific articles and proteins ...
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Bounded Diameter Clustering Scheme For Protein Interaction Networks
... Identifying protein clusters within a biological systems is essential for understanding of the high-level organization of the ...from protein interaction ...
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Protein-protein interaction networks: probing disease mechanisms using model systems
... related protein-1 (LRP-1), a recently identified phagocytic receptor for myelin debris in the central nervous system ...in protein translation ...synaptic protein complexes that had been previously ...
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Web servers, databases, and algorithms for the analysis of protein interaction networks
... data-source, but other multi-species genome-wide databases (e.g. MINT [37] or APID [38]) could also be used. For negative examples, we require that the two proteins either be disconnected in the PPI network or be at ...
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The Hsp90 Chaperone Machinery: An Important Hub in Protein Interaction Networks
... shock protein 90 (Hsp90) represents one of the most conserved proteins in living organisms and is present in all kingdoms of life except for ...in protein homoeostasis and ...
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Superclusteroid: a Web tool dedicated to data processing of protein-protein interaction networks
... By using the UniProt database (Magrane and Consortium , 2011), it can be seen that P38334 is part of the TRAPP complex (Sacher et al., 1998), which according to Gene Ontology data (Barrell et al., 2009), is a large ...
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Identification of Candidate Genes related to Bovine Marbling using Protein-Protein Interaction Networks
... interesting protein nodes that may or may not be important in the core network, but which are large-BC nodes in the extended network: Casein kinase 2, alpha 1 polypeptide (CSNK2A1), Protein kinase C, alpha ...
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