Rate limiting
Inheritance of Rate-Limiting Foliar Resistance to Anthracnose Crown Rot and Fruit Rot in Cultivated Strawberry
... 1968). Rate-limiting resistance has been described in leaf tissue of other crop species and has been deployed in resistant germplasm to inhibit the spread of inoculum to economically valuable tissues to ...
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Second-strand synthesis is a rate-limiting step for efficient transduction by recombinant adeno-associated virus vectors.
... Ad E4 ORF6 and UV treatment enhance second-strand DNA synthesis by rAAV. To identify the rate-limiting step in rAAV transduction, we initially assayed the effect of E4 ORF6 on rAAV uncoating. 293 cells were ...
9
Linear Eyring plots conceal a change in rate limiting step in an enzyme reaction
... is rate-limiting at high temperatures for the psychrophilic enzyme, either interconversion between enzyme − substrate and en- zyme − product complexes or a step prior to it limits the rate at low ...
5
Meis1 is an essential and rate-limiting regulator of MLL leukemia stem cell potential
... the rate of progression of immortalized cells to LSCs that initiate and sustain ...potential rate-limiting role for MEIS gene expression comparable with mouse ...
15
The regulation and importance of glucose uptake in the isolated Atlantic cod heart: rate limiting steps and effects of hypoxia
... the rate of glucose phosphorylation is greater than the rate of transport into the cell and that the rate-limiting step in the utilization of extracellular glucose is transmembrane ...
10
Transcriptional stimulation of rate limiting components of the autophagic pathway improves plant fitness
... Autophagy is a major catabolic process whereby autophagosomes deliver cytoplasmic content to the lytic com- partment for recycling. Autophagosome formation requires two ubiquitin-like systems conjugating Atg12 with Atg5, ...
18
Exploring the rate-limiting steps in visual phototransduction recovery by bottom-up kinetic modeling
... Importantly, the new Rec-RK implementation did not significantly alter the dynamics of the model, while its simpler implementation compared to the previous version of the model allowed easier manipulation of these two ...
18
The influence of drug distribution and drug-target binding on target occupancy: The rate-limiting step approximation
... our rate-limiting step approximation has been visualized in ...and rate-limiting step: Model 4) produce similar results as Model 1, although Model 4 seems to approximate Model 1 a bit better ...
7
Load balancing and rate limiting based algorithms for improving cloud computing performance
... of rate limiting known as dis- tributed rate limiting (DRL) ...limit. Rate limiting is also an important concept in the maintenance of a reasonable QoS inside the data ...
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Temporal Rate Limiting: cloud elasticity at a flat fee
... Temporal Rate Limiting (TRL), a purchase policy that permits a customer to allocate optimally a specified purchase budget over a predefined period of ...
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Evidence that calcineurin is rate limiting for primary human lymphocyte activation
... is rate-limiting for lymphocyte ...of rate-limiting enzymes may be a general theme in immunosuppressive drugs used for maintenance therapy, where the immune response must be blunted for ...
9
N acetyltransferase is not the rate limiting enzyme of melatonin synthesis at night
... Early studies investigating the mechanism of melatonin production focused on in vitro characterization of the enzymes responsible for its biosynthesis. HIOMT was more easily characterized, principally because it lacks a ...
6
Transport as the Rate-Limiting Step in the Incorporation of Uridine into Mengovirus Ribonucleic Acid in Novikoff Rat Hepatoma Cells
... These results are similar to those obtained with uninfected cells 9, and, combined with the fact that neither adenosine nor persantin has any effect on the uridine kinase of NISI-67 cell[r] ...
7
Complex I is rate limiting for oxygen consumption in the nerve terminal
... Titration of Complex II/III Activity—Myxothiazol decreased the rate of synaptosomal oxygen consumption and the activity FIGURE 1. Rotenone titration of synaptosomal oxygen consumption and complex I activity. Rat ...
7
Insulin transport across capillaries is rate limiting for insulin action in dogs
... During the final 3 h, both plasma and lymph insulin returned to basal levels but again, lymph insulin was slower than insulin in plasma; plasma insulin returned to basal within 8+2 minm [r] ...
10
Allosteric activation shifts the rate limiting step in a short form ATP phosphoribosyltransferase
... concentration of PaATPPRT used in the experiment (19 μ M). Two main reasons may account, separately or in combination, for this result without invoking the unlikely scenario where ca. 75% of enzyme molecules are ...
11
Improving squalene production by enhancing the NADPH/NADP+ ratio, modifying the isoprenoid-feeding module and blocking the menaquinone pathway in Escherichia coli
... of rate-limiting enzymes in isopre- noid pathway, the modification of isoprenoid-feeding module and the blocking of menaquinone pathway, pro- viding efficient methods to increase the squalene yield in ...
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Combinatory strategy for characterizing and understanding the ethanol synthesis pathway in cyanobacteria cell factories
... In vitro reconstitution and quantitative titrations of PDCzm and slr1192 indicated that conversion process from pyruvate to acetaldehyde was the rate-limiting step of the ethanol synthesis pathway, thus ...
12
Energy substrate metabolism in fresh and stored human platelets
... That ATP was rate limiting in oleate oxidation by the platelet in the hypoosmolaric medium appears unlikely for the following reasons: a glucose phosphorylation as indicated by oxidation[r] ...
10
Nampt-Mediated Nad+ Homeostasis in Skeletal Muscle: Implications for Healthy Aging
... dinucleotide (NAD), as a co-factor and signaling intermediate uniquely positioned to modulate whole-body energy balance through transcriptional and post-translational mechanisms. Though it has long been known that NAD ...
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