Recombinant Human Bone Morphogenetic Protein
Allogeneic morphogenetic protein vs. recombinant human bone morphogenetic protein-2 in lumbar interbody fusion procedures: a radiographic and economic analysis
... a recombinant human bone morphogenetic protein-2 (Infuse, Medtronic ...ectopic bone formation and potentially cancer, leading clinicians to question the clinical benefit versus ...
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Management of subtrochanteric femur fractures with internal fixation and recombinant human bone morphogenetic protein 7 in a patient with osteopetrosis: a case report
... prophylactic bone grafting of the right side at the same ...of recombinant human bone morphogenetic protein-7 (rhBMP-7) to his right- sided fracture, citing his history of ...
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THE EFFECT OF RECOMBINANT HUMAN BONE MORPHOGENETIC PROTEIN-2 ON THE OSSEOINTEGRATION OF TEMPORARY ANCHORAGE DEVICES
... of recombinant human bone morphogenetic protein-2 (rhBMP-2) on the ability of temporary anchorage devices (TADs) to osseointegrate was ...INFUSE® Bone Graft (recombinant ...
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The effect of locally delivered recombinant human bone morphogenetic protein-2 with hydroxyapatite/tri-calcium phosphate on the biomechanical properties of bone in diabetes-related osteoporosis
... Background Recombinant human bone morphogenetic protein-2 (rhBMP-2) is particularly effective in improving osteogenesis in patients with diminished bone healing capabilities, ...
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Effects of Polycaprolactone Tricalcium Phosphate, Recombinant Human Bone Morphogenetic Protein 2 and Dog Mesenchymal Stem Cells on Bone Formation: Pilot Study in Dogs
... and bone formation of dog mesenchymal stem cells (dMSCs) in the graft material by using Polycaprolactone-tricalcium phosphate (PCL-TCP), auto-fibrin glue (AFG), recombinant human bone ...
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Comparison of two independent systematic reviews of trials of recombinant human bone morphogenetic protein-2 (rhBMP-2): the Yale Open Data Access Medtronic Project
... The Human Investigation Committee at Yale University determined that this study is not consid- ered to be Human Subjects Research and did not require further ...
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Sustained delivery of recombinant human bone morphogenetic protein-2 from perlecan domain I - functionalized electrospun poly (ε-caprolactone) scaffolds for bone regeneration
... the human bone marrow and in other mesenchymal tis- sues, perlecan/HSPG2 is a large, secreted heparan sulfate proteoglycan with five distinct domains, each endowed with the unique ability to affect cellular ...
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Combined effect of bisphosphonate and recombinant human bone morphogenetic protein 2 on bone healing of rat calvarial defects
... experiment has attempted to perform application by using BMP and bisphosphonate together. The concentration of BMP was determined from the manufacturer, and the con- centration of bisphosphonate is known to use a ...
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Rapid bone regeneration by Escherichia coli-derived recombinant human bone morphogenetic protein-2 loaded on a hydroxyapatite carrier in the rabbit calvarial defect model
... new bone volume at 8 weeks ...guided bone regeneration is clinically required, HAP soaked in ErhBMP-2 can be applied with- out a membrane, since HAP can promote rapid initial bone ...guided ...
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Recombinant human Bone Morphogenetic Protein-2 (rhBMP-2) in posterolateral lumbar spine fusion: complications in the elderly
... a bone void filler (BVF) such as Mastergraft (Medtronic, Memphis, TN) or allograft bone (Musculo- skeletal Transplant Foundation, MTF, West Chester, PA) and placed onto the transverse processes and ...
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Schwartz, Daniel (2005): Development of an Aqueous Suspension of Recombinant Human Bone Morphogenetic Protein-2 (rhBMP-2): Entwicklung einer wässrigen Suspension des recombinanten menschlichen Knochenwachstumsproteins-2 (rhBMP-2). Dissertation, LMU München: Fakultät für Chemie und Pharmazie
... induce bone formation. This ability can be applied to the field of bone tissue engineering, ...accelerate bone regeneration at a skeletal site after fracture or in plastic ...the protein is ...
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β Tricalcium Phosphate Combined with Recombinant Human Bone Morphogenetic Protein 2: A Substitute for Autograft, Used for Packing Interbody Fusion Cages in the Canine Lumbar Spine
... outcomes as autogenous bone in the examinations of micro- radiographs and histological sections. Thus, we expect that - TCP can be used as a substitute for autogenous bone for the interbody fusion cages. ...
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Bone regenerative effect of recombinant human bone morphogenetic protein-2 after cyst enucleation
... Unfortunately, however, there have been some limi- tations to the use of rhBMP-2 despite the successful outcomes described above. These include the shorter half-life of BMP-2 and its rapid elimination at the ap- ...
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OSSEOINTEGRATION OF TEMPORARY ANCHORAGE DEVICES USING RECOMBINANT HUMAN BONE MORPHOGENETIC PROTEIN-2
... subperiosteal implants for many years. In addition, titanium easily passivates to form a protective oxide layer, which allows the apposition of proteins and tissue to the metal surface [7]. Thus, titanium itself promotes ...
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Depot injectable biodegradable nanoparticles loaded with recombinant human bone morphogenetic protein-2: preparation, characterization, and in vivo evaluation
... Results: The results found that NPs formula prepared using blend of PLGA and PCL in 4:2 (w/w) ratio showed the best sustained-release pattern with lower initial burst, and showed up to 62.7% yield, 64.5% encapsulation ...
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Original Article rhBMP-2 applied as support of distraction osteogenesis: a split-mouth histological study over nonhuman primates mandibles
... the recombinant human bone morphogenetic protein type 2 (rhBMP2) to a collagen matrix applied on a distraction osteogenesis device would help healing in the middle new formed ...bovine ...
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“Evolving Trends in Biopolymer Based Drug Delivery Systems: An Overview” by Soruba Evangeline, Vickram Sundaram, Ramesh Pathy Manian, Sridharan Balasundaram, India.
... structural protein, which gives structure and support to the tissues connecting them with the ...containing recombinant human bone morphogenetic protein 2 (rhBMP-2) was studied ...
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Siliceous mesostructured cellular foams/ poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) composite biomaterials for bone regeneration
... the recombinant human bone morphogenetic protein (rhBMP-2) on the surfaces of the scaffolds, the scaffolds were immersed in 5 mL rhBMP-2 solutions (100 µ g/mL) at room temperature for ...
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Bone Morphogenetic Protein (BMP)-7 expression is decreased in human hypertensive nephrosclerosis
... primary and immortalised human proximal tubule cells [11]. Our functional data showed that BMP-7 was able to reverse the TGF- b -induced EMT in human proximal tubule cells by using high concentrations of ...
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Hypertrophy is induced during the in vitrochondrogenic differentiation of human mesenchymal stem cells by bone morphogenetic protein 2 and bone morphogenetic protein 4 gene transfer
... using recombinant proteins, where BMP-4 was identified as a strong inducer of chondro- genesis [36], which produced less hypertrophy compared with BMP-2 ...and bone formation when delivered as ...
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