recombinant human bone morphogenetic protein-2
Effects of Polycaprolactone Tricalcium Phosphate, Recombinant Human Bone Morphogenetic Protein 2 and Dog Mesenchymal Stem Cells on Bone Formation: Pilot Study in Dogs
... and bone formation of dog mesenchymal stem cells (dMSCs) in the graft material by using Polycaprolactone-tricalcium phosphate (PCL-TCP), auto-fibrin glue (AFG), recombinant human bone ...
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THE EFFECT OF RECOMBINANT HUMAN BONE MORPHOGENETIC PROTEIN-2 ON THE OSSEOINTEGRATION OF TEMPORARY ANCHORAGE DEVICES
... of recombinant human bone morphogenetic protein-2 (rhBMP-2) on the ability of temporary anchorage devices (TADs) to osseointegrate was ...into 2 types of ...
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Allogeneic morphogenetic protein vs. recombinant human bone morphogenetic protein-2 in lumbar interbody fusion procedures: a radiographic and economic analysis
... a recombinant human bone morphogenetic protein-2 (Infuse, Medtronic ...ectopic bone formation and potentially cancer, leading clinicians to question the clinical benefit ...
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The effect of locally delivered recombinant human bone morphogenetic protein-2 with hydroxyapatite/tri-calcium phosphate on the biomechanical properties of bone in diabetes-related osteoporosis
... Background Recombinant human bone morphogenetic protein-2 (rhBMP-2) is particularly effective in improving osteogenesis in patients with diminished bone healing ...
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Improved osseointegration of dental titanium implants by TiO<sub>2</sub> nanotube arrays with recombinant human bone morphogenetic protein-2: a pilot in vivo study
... TiO 2 nanotube arrays on the surface of dental implants were fabricated by two-step anodic ...on bone-implant contact were researched by a pilot in vivo ...TiO 2 nanotube arrays and ...
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Combined effect of bisphosphonate and recombinant human bone morphogenetic protein 2 on bone healing of rat calvarial defects
... new bone formation areas on H-E stained ...formed bone outlines, is easily ...then 2 slides from each group were selected in the 2, 4, 8 ...new bone formation area, 4 sites were ...
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Schwartz, Daniel (2005): Development of an Aqueous Suspension of Recombinant Human Bone Morphogenetic Protein-2 (rhBMP-2): Entwicklung einer wässrigen Suspension des recombinanten menschlichen Knochenwachstumsproteins-2 (rhBMP-2). Dissertation, LMU München: Fakultät für Chemie und Pharmazie
... to bone, cartilage has a limited capacity to heal after ...As bone morphogenesis is a sequential cascade with a cartilagenous intermediate formed (endrochondral ossification), BMPs are as well cartilage ...
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Rapid bone regeneration by Escherichia coli-derived recombinant human bone morphogenetic protein-2 loaded on a hydroxyapatite carrier in the rabbit calvarial defect model
... of recombinant human BMP-2 (rhBMP-2) [4, ...cause protein yields are ...in bone regeneration ...the bone gap of a sinus window [8] and ErhBMP-2-coated implants ...
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β Tricalcium Phosphate Combined with Recombinant Human Bone Morphogenetic Protein 2: A Substitute for Autograft, Used for Packing Interbody Fusion Cages in the Canine Lumbar Spine
... outcomes as autogenous bone in the examinations of micro- radiographs and histological sections. Thus, we expect that - TCP can be used as a substitute for autogenous bone for the interbody fusion cages. ...
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OSSEOINTEGRATION OF TEMPORARY ANCHORAGE DEVICES USING RECOMBINANT HUMAN BONE MORPHOGENETIC PROTEIN-2
... stimulating bone growth in a variety of applications. Specifically, INFUSE® Bone Graft (Medtronic Sofamor Danek, Memphis, TN), which consists of rhBMP-2 in combination with an absorbable collagen ...
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Recombinant human Bone Morphogenetic Protein-2 (rhBMP-2) in posterolateral lumbar spine fusion: complications in the elderly
... poor bone quality void of osteoinductive ma- terial in elderly patients, a large amount of iliac crest bone graft is ...of bone harvest related com- plications, and frequently is inadequate or ...
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Comparison of two independent systematic reviews of trials of recombinant human bone morphogenetic protein-2 (rhBMP-2): the Yale Open Data Access Medtronic Project
... Adverse events attributed to rhBMP-2 began to be re- ported. In 2008, the US Food and Drug Administration (FDA) issued a warning about dangerous side effects as- sociated with rhBMP-2 use in anterior ...
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Bone regenerative effect of recombinant human bone morphogenetic protein-2 after cyst enucleation
... Methods: Under general anesthesia, 10 patients (12 lesions) underwent oral or maxillofacial surgery for cyst enucleation. Postoperatively, 12 lesions were divided into two groups: group A (six lesions) was treated with ...
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Sustained delivery of recombinant human bone morphogenetic protein-2 from perlecan domain I - functionalized electrospun poly (ε-caprolactone) scaffolds for bone regeneration
... The goal of this study was to determine if functionaliza- tion of electrospun PCL fibers with PlnD1 enhances rhBMP-2 binding and if subsequently released rhBMP-2 presents bioactivity. To achieve this, we ...
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Depot injectable biodegradable nanoparticles loaded with recombinant human bone morphogenetic protein-2: preparation, characterization, and in vivo evaluation
... Results: The results found that NPs formula prepared using blend of PLGA and PCL in 4:2 (w/w) ratio showed the best sustained-release pattern with lower initial burst, and showed up to 62.7% yield, 64.5% ...
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“Evolving Trends in Biopolymer Based Drug Delivery Systems: An Overview” by Soruba Evangeline, Vickram Sundaram, Ramesh Pathy Manian, Sridharan Balasundaram, India.
... structural protein, which gives structure and support to the tissues connecting them with the ...containing recombinant human bone morphogenetic protein 2 (rhBMP-2) ...
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Siliceous mesostructured cellular foams/ poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) composite biomaterials for bone regeneration
... for bone regeneration were prepared by combining poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) (PHBHHx) with siliceous mesostructured cellular foams (SMC), using the porogen leaching ...and recombinant ...
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Hypertrophy is induced during the in vitrochondrogenic differentiation of human mesenchymal stem cells by bone morphogenetic protein 2 and bone morphogenetic protein 4 gene transfer
... using recombinant proteins, where BMP-4 was identified as a strong inducer of chondro- genesis [36], which produced less hypertrophy compared with BMP-2 ...and bone formation when delivered as ...
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Original Article rhBMP-2 applied as support of distraction osteogenesis: a split-mouth histological study over nonhuman primates mandibles
... the recombinant human bone morphogenetic protein type 2 (rhBMP2) to a collagen matrix applied on a distraction osteogenesis device would help healing in the middle new formed ...
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Loading BMP-2 on nanostructured hydroxyapatite microspheres for rapid bone regeneration
... In this study, we prepared nHAp microspheres with a nanostructure that could enhance the loading ability of rhBMP-2 and prolong its release time. Our results show that the rhBMP-2-loaded nHAp microspheres ...
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