regulatory element
Effects of sterol regulatory element-binding protein (SREBP) in chickens
... Sterol regulatory element binding proteins (SREBP) are basic helix-loop-helix-leucine zipper (bHLH-Zip) tran- scription factors that play an important role in control- ling genes involved in the ...
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The pattern of development for gene expression of sterol regulatory element binding transcription factor 1 in pigs
... Sterol regulatory element-binding transcription factor 1 (SREBF1) has been implicated as a key regu- lator of adipocyte differentiation and lipid ...
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Identification of a cis-regulatory element by transient analysis of co-ordinately regulated genes
... served motif was found in both plus and minus orienta- tions and upstream of the 5' UTR where annotation is available. This motif was absent (P-value < 0.119) from the 25 promoter fragments that were initially ...
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Sterol Regulatory Element Binding Proteins; Central Metabolic Regulators of Natural Killer Cells
... In many cell types, the activity of sterol regulatory element binding proteins (SREBP) is induced downstream of mTORC1 activation (Porstmann et al. 2008). SREBP transcription factors are a group of ...
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Sterol Regulatory Element Binding Proteins in Fungi: Hypoxic Transcription Factors Linked to Pathogenesis
... sterol regulatory element binding proteins (SREBPs), which act as principal regulators of both cellular cholesterol uptake and de novo synthesis ...unique regulatory mechanism in which sterols ...
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Prolactin Regulatory Element Binding Protein Is Involved in Hepatitis C Virus Replication by Interaction with NS4B
... The present research suggests that host cofactors involved in the HCV replication complex could affect HCV replication in three ways. First, host cofactors, such as PI4KIII␣ and VAP-A, participate in the formation of the ...
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A Novel Downstream Regulatory Element Cooperates with the Silencing Machinery to Repress EPA1 Expression in Candida glabrata
... In this study, we showed that EPA1 expression is negatively regulated by two independent mechanisms: subtelomeric silencing and a telomere-independent, novel mode of nega- tive regulation, dependent on a cis-acting NE ...
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An ATF/CREB site is the major regulatory element in the human herpesvirus 6 DNA polymerase promoter.
... Mutational analysis also revealed that the major upstream promoter regulatory element required for transcriptional activity in HHV-6-infected cells is a palindromic ATF/CREB transcriptio[r] ...
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In vivo identification of a negative regulatory element in the mouse renin gene using direct gene transfer
... DBA/2J mouse contains two renin gene loci (Ren1d and Ren2d). Ren2d but not Ren1d is expressed in submandibular gland (SMG) while both are expressed in the kidney. Based on vitro studies, we have postulated that a ...
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Identification of an effective siRNA target site and functional regulatory elements, within the hepatitis B virus posttranscriptional regulatory element
... The HBV post-transcriptional regulatory element is highly conserved among the mammalian hepadnaviridae [23]. As the sequence of the PRE also encodes the P pro- tein, the conservation may partly be due to ...
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An arthropod cis-regulatory element functioning in sensory organ precursor development dates back to the Cambrian
... arthropod regulatory element that functions during the selection of neural ...A regulatory element, the sensory organ precursor enhancer (SOPE), is required for this ...
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DREAM (Downstream Regulatory Element Antagonist Modulator) contributes to synaptic depression and contextual fear memory
... downstream regulatory element antagonist modulator (DREAM), a multifunctional Ca 2+ -binding protein, binds specifically to DNA and several nucleoproteins regulating gene expression and with proteins ...
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Conservation of the Sterol Regulatory Element-Binding Protein Pathway and Its Pathobiological Importance in Cryptococcus neoformans
... sterol regulatory element-binding protein (SREBP) homolog, Sre1, is important for adap- tation and growth of Cryptococcus neoformans in the mouse brain, where oxygen concentration and nutritional conditions ...
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A Negative Regulatory Element Controls mRNA Abundance of the Leishmania mexicana Paraflagellar Rod Gene PFR2
... indicating that p2CWT and p2CH retained the native down- stream splice site that specifies the site of 3⬘ polyadenylation. 3 ⴕ UTR sequences confer stage specificity to PFR2 mRNA accumulation. The 3⬘ UTR participates in ...
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Transcriptionally Active MuDR, the Regulatory Element of the Mutator Transposable Element Family of Zea mays, Is Present in Some Accessions of the Mexican land race Zapalote chico
... All of the other exotic lines examined, including Argen- tine popcorn, Tama flint, Strawberry popcorn, Papago flint, gourd seed, Northern flint, Z. perennis, Z. diploper- ennis, and five teosinte types (see materials and ...
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A negative regulatory element in the human papillomavirus type 16 genome acts at the level of late mRNA stability.
... We have previously described a negative regulatory element in the human papillomavirus type 16 HPV16 genome 21 which is located immediately upstream of the late mRNA 3' processing signal[r] ...
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Oct4 regulates DNA methyltransferase 1 transcription by direct binding of the regulatory element
... Using bioinformatic analysis, an octamer motif was predicted in the region between − 475 and − 468 bp relative to TSS. Therefore, promoter analysis was per- formed to investigate whether Dnmt1 transcription is regulated ...
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Sterol regulatory element binding protein-dependent regulation of lipid synthesis supports cell survival and tumor growth
... sterol regulatory element binding pro- teins (SREBPs), a small family of lipogenic transcription fac- ...sterol regulatory element (SRE)-sequences in the promoters of its target genes ...
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Woodchuck Hepatitis Virus Contains a Tripartite Posttranscriptional Regulatory Element
... posttranscriptional regulatory element (HBVPRE) is an orientation-dependent cis-acting RNA element that par- tially overlaps with enhancer I and is required for the cytoplas- mic localization of HBV ...
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The hepatitis B virus posttranscriptional regulatory element is composed of two subelements.
... cis-acting regulatory element which facilitates the cyto- plasmic localization of unspliced transcripts ...the element. The HBV posttranscriptional regulatory element (HB- VPRE) can ...
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