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Renal Cell Cancer

Epidemiologic characteristics and risk factors for renal cell cancer

Epidemiologic characteristics and risk factors for renal cell cancer

... for renal cell ...decreased renal cell cancer risk, and differential observations between men and ...of renal cell cancer was recently published, based on results ...

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GOLPH2 expression in renal cell cancer

GOLPH2 expression in renal cell cancer

... prostate cancer GOLPH2 is up-regulated on mRNA and protein level in comparison to the normal glandular tissue ...In renal cell cancer, this seems not to be the case and the high GOLPH2 ...

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Epigenetic sampling effects : nephrectomy modifies the clear cell renal cell cancer methylome

Epigenetic sampling effects : nephrectomy modifies the clear cell renal cell cancer methylome

... Abstract: Currently, it is unclear to what extent sampling procedures affect the epigenome. Here, this phenomenon was evaluated by studying the impact of artery ligation on DNA methylation in clear cell ...

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Timing the landmark events in the evolution of clear cell renal cell cancer : TRACERx renal

Timing the landmark events in the evolution of clear cell renal cell cancer : TRACERx renal

... clear cell renal cell carcinoma follows strongly preferred evolutionary ...the cancer may not be diagnosed for another 30–50 ...clear cell renal cell carcinoma is nearly ...

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Sunitinib for advanced renal cell cancer

Sunitinib for advanced renal cell cancer

... metastatic renal cell carcinoma previously treated with cytokine ...any renal cancer histol- ogy between January and July 2003 in a single center setting (Motzer et al ...

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Update on vaccine development for renal cell cancer

Update on vaccine development for renal cell cancer

... posed that a successful combinational therapeutic platform must include the integration of appropriate immunogeneic tumor antigens in order to focus immunity toward carci- noma cells with adjuvants that activate and ...

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Original Article Circulating levels of adipocytokines omentin-1 and adiponectin in patients with bladder cancer

Original Article Circulating levels of adipocytokines omentin-1 and adiponectin in patients with bladder cancer

... Omentin-1 is newly identified in human adipose tissue with 34 kDa MW, which adipocytokine is depot-specific and could enhance the activity of insulin but down-regulated by high glucose [10-12]. Adiponectin is a protein ...

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Nuclear Pedigree Criteria for the Identification of Individuals Suspected to be at Risk of an Inherited Predisposition to Renal Cancer

Nuclear Pedigree Criteria for the Identification of Individuals Suspected to be at Risk of an Inherited Predisposition to Renal Cancer

... clear cell carcinomas represent about 3% of all visceral cancers and account for approximately 85% of renal cancers in ...which renal cell cancer may occur, only four syndromes with an ...

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The prognostic value of serum amyloid A in solid tumors: a meta-analysis

The prognostic value of serum amyloid A in solid tumors: a meta-analysis

... cancer cell lines [27, ...including renal cell cancer, breast cancer, gastric cancer, oesopha- geal cancer, rectal cancer, hepatocellular cancer, pan- ...

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Radioimmunotherapy for delivery of cytotoxic radioisotopes - current status and challenges

Radioimmunotherapy for delivery of cytotoxic radioisotopes - current status and challenges

... renal cell cancer patients, resulting in reduced tumor uptake of 111 In-bevacizumab and. 15[r] ...

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Biomarkers of evasive resistance predict disease progression in cancer patients treated with antiangiogenic therapies

Biomarkers of evasive resistance predict disease progression in cancer patients treated with antiangiogenic therapies

... hepatocellular cancer (n = 11), renal cell cancer (n = 7) and non-small cell lung cancer (n = ...endothelial cell-specific chemotaxis regulator (ECSCR), reflecting the ...

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Overall survival in renal cell carcinoma after introduction of targeted therapies: a Norwegian population-based study

Overall survival in renal cell carcinoma after introduction of targeted therapies: a Norwegian population-based study

... In the multivariate analysis of factors that might impact OS in the mRCC population, administration of at least 1 targeted therapy, of which sunitinib was the most prescribed first-line therapy, was clearly associated ...

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Somatic mutations in renal cell carcinomas from Chinese patients revealed by targeted gene panel sequencing and their associations with prognosis and PD-L1 expression

Somatic mutations in renal cell carcinomas from Chinese patients revealed by targeted gene panel sequencing and their associations with prognosis and PD-L1 expression

... In recent years, immunotherapy has played an increas- ingly important role in the treatment of advanced RCC and other malignancies. Based on the current under- standing, programmed death-1 (PD-1) can combine with ...

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RETRACTED ARTICLE: Collecting duct carcinoma of the kidney: a clinicopathological study of five cases

RETRACTED ARTICLE: Collecting duct carcinoma of the kidney: a clinicopathological study of five cases

... of renal hilum was ob- served in 2 cases, containing surrounding of tumor tis- sue on the renal artery in 1 case; that the diameter of tumors was between ...around renal sinus as well as pelvis ...

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The association between hypoxia-inducible factor-1 α gene G1790A polymorphism and cancer risk: a meta-analysis of 28 case–control studies

The association between hypoxia-inducible factor-1 α gene G1790A polymorphism and cancer risk: a meta-analysis of 28 case–control studies

... reducing cell adhesion, degrading extracellular matrix through up-regulating matrix metal- loproteinase (MMPs) or lysyl oxydase (LOX) [33] and increasing chemotaxis ...

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A meta-analysis of hypoxia inducible factor 1-alpha (HIF1A) gene polymorphisms: association with cancers

A meta-analysis of hypoxia inducible factor 1-alpha (HIF1A) gene polymorphisms: association with cancers

... apoptosis, cell proliferation, glucose metabolism, erythropoiesis, iron metabolism and ...on cancer risk in different popula- tions; however reported results varied across studies and remain inconclusive ...

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Tumor control with PD-1 inhibition in a patient with concurrent metastatic melanoma and renal cell carcinoma

Tumor control with PD-1 inhibition in a patient with concurrent metastatic melanoma and renal cell carcinoma

... non-small cell lung cancer, bladder cancer, and Hodgkin’s ...immune cell infiltrate, expression of PD-L1 on tumor and/or immune cells, and an elevated mutational load with corresponding ...

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B7x—from bench to bedside

B7x—from bench to bedside

... in cancer tissues, B7x is also an attractive target for cancer immunotherapy-blocking antibodies such as mAbs, scFvs, ADCs, CD3 BiTEs and ...and cancer is currently underway, and the results can be ...

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Appropriation of the ‘Witch’ Stigma as White Women's Self-Empowerment

Appropriation of the ‘Witch’ Stigma as White Women's Self-Empowerment

... and cell death in cancers across 8 solid tumor cell ...lung cancer due to the sensitivity of lung cancer cell lines to the compound in addition to the exceedingly poor prognoses of lung ...

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CBFA2T2 is associated with a cancer stem cell state in renal cell carcinoma

CBFA2T2 is associated with a cancer stem cell state in renal cell carcinoma

... For Western blot assay, 786-O and A498 cells trans- fected with the siRNAs against CBFA2T2 or control siRNA for 72 h were washed two times with ice cold phosphate-buffered saline (PBS) and lysed in RIPA buffer (50 mM ...

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