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Residual disease

Monitoring of Minimal Residual Disease (MRD) in Chronic Myeloid Leukemia: Recent Advances

<p>Monitoring of Minimal Residual Disease (MRD) in Chronic Myeloid Leukemia: Recent Advances</p>

... minimal residual disease levels, 97,102,104,105 where geno- mic DNA could be more informative than mRNA for the detection of residual disease or for very immature selected ...positive ...

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Evaluation of Minimal Residual Disease in Acute Myeloid Leukemia with NPM1 Marker

Evaluation of Minimal Residual Disease in Acute Myeloid Leukemia with NPM1 Marker

... Background: Minimal residual disease (MRD) tests provide early identification of hematologic relapse and timely management of acute myeloid leukemia (AML) patients. Approximately, 50% of AML patients do not ...

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Minimal residual disease and circulating tumor cells in breast cancer

Minimal residual disease and circulating tumor cells in breast cancer

... their disease. Minimal residual disease (MRD) after potentially curative surgery for BC is thought to contri- bute to disease relapse and to be the target of adjuvant ...

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Studying the Concept of Minimal Residual Disease Detection in Cases of CLL

Studying the Concept of Minimal Residual Disease Detection in Cases of CLL

... Despite improvements in the treatment of haematological malignancies over the last few decades, many patients relapse after an initial response to treatment. Such relapses are derived from the same clone detected at the ...

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Predictors of residual disease after loop electrosurgical excision procedure

Predictors of residual disease after loop electrosurgical excision procedure

... The study aims to evaluate the importance of resection margins in the risk of residual disease (RD) and to investigate other factors that could potentially predict RD before patients engage in follow-up. ...

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Strategies for minimal residual disease detection: current perspectives

<p>Strategies for minimal residual disease detection: current perspectives</p>

... Abstract: Currently, the post-remission treatment in acute leukemia is based on the genetic profile of leukemic cells at diagnosis (ie, FLT3 ITD positivity) and on the level of measur- able residual disease ...

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Minimal residual disease- and graft-vs.-host disease-guided multiple consolidation chemotherapy and donor lymphocyte infusion prevent second acute leukemia relapse after allotransplant

Minimal residual disease- and graft-vs.-host disease-guided multiple consolidation chemotherapy and donor lymphocyte infusion prevent second acute leukemia relapse after allotransplant

... In persons receiving an allotransplant for acute leukemia, we reported an association between a positive minimal residual disease (MRD)-test after transplant and an increased risk of subsequent relapse ...

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Early Postoperative CT Scanning for Juvenile Nasopharyngeal Angiofibroma: Detection of Residual Disease

Early Postoperative CT Scanning for Juvenile Nasopharyngeal Angiofibroma: Detection of Residual Disease

... Recurrence is growth of residual disease (RD). Total removal of JNA is difficult when invasion of the skull base occurs (3). Some tumor may be left in place even when the resection is deemed complete, ...

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Impact of obesity on breast cancer recurrence and minimal residual disease

Impact of obesity on breast cancer recurrence and minimal residual disease

... local residual tumor cells in the mammary gland following therapy is prognostic for relapse at distant sites [55, ...HER2− residual disease [59–61] and HER2− recurrent tumors ...that residual ...

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Residual disease activity and treatment adjustments in psoriatic arthritis in current clinical practice

Residual disease activity and treatment adjustments in psoriatic arthritis in current clinical practice

... with residual disease activity in the group treated with a second TNFi, keeping in mind the new treatments such as ustekinumab only recently came to market and apremilast and secukinumab were not avail- ...

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Original Article Predictive value of clinicopathological characteristics for residual disease in subsequent hysterectomy specimens following cervical conization

Original Article Predictive value of clinicopathological characteristics for residual disease in subsequent hysterectomy specimens following cervical conization

... contained residual disease, compared to 88% of specimens when the post-cone ECC was ...of disease could predict disease ...predict residual dys- plasia. The probabilities of having ...

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The relation between end of induction minimal residual disease and different risk factors in patients with acute lymphoblastic leukemia

The relation between end of induction minimal residual disease and different risk factors in patients with acute lymphoblastic leukemia

... minimal residual disease, can be satisfactory (10-12), where the advanced treatment for increasing survival of children with cancers, especially those with ALL is very important ...minimal residual ...

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Evolutionary dynamics of residual disease in human glioblastoma.

Evolutionary dynamics of residual disease in human glioblastoma.

... Residual disease samples diverged early from the rest of the tu- mour mass in the majority of patients for which M samples were available, with particular evidence for SP49, SP52, SP57, A44, SP28 for which ...

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Current challenges in glioblastoma : intratumour heterogeneity, residual disease and models to predict disease recurrence

Current challenges in glioblastoma : intratumour heterogeneity, residual disease and models to predict disease recurrence

... of residual disease in the subependymal zone ...to disease recur- rence by harboring the tumor-initiating cells (TICs) that comprise residual disease (see Figure 1) ...

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Minimal residual disease in cancer of the oesophagus and gastro oesophageal junction

Minimal residual disease in cancer of the oesophagus and gastro oesophageal junction

... of disease extent, although providing reliable information about populations of patients, does not allow accurate prognoses to be made on an individual patient ...

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Universal monitoring of minimal residual disease in acute myeloid leukemia

Universal monitoring of minimal residual disease in acute myeloid leukemia

... Markers encoded by aberrantly expressed genes, including some previously associated with leukemia stem cells, were studied by flow cytometry in 240 patients with AML and in nonleukemic[r] ...

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Modeling Breast Cancer Dormancy and Recurrence Following Oncogenic Pathway Inhibition

Modeling Breast Cancer Dormancy and Recurrence Following Oncogenic Pathway Inhibition

... of residual disease. Residual disease can be detected as circulating tumor cells (CTCs) in the blood, or disseminated tumor cells (DTCs) in the bone marrow, by identifying cells expressing ...

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Neoadjuvant chemotherapy for IIIC stage ovarian cancer - case report

Neoadjuvant chemotherapy for IIIC stage ovarian cancer - case report

... (residual disease >1 cm) was achieved in 59% of patients in primary surgery and in 24% of treated following primary chemotherapy ...The residual disease of 0 cm in stage IV was obtained in ...

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Current Indications of Bone Marrow Transplantation (BMT) in Pediatric Malignant Conditions a Review

Current Indications of Bone Marrow Transplantation (BMT) in Pediatric Malignant Conditions a Review

... intensive induction chemotherapy is another poor prognostic factor. Some of these patients may never enter into CR1 and they do not benefit from HSCT while still having active leukemia. Even if remission is achieved with ...

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Incorporating robotic surgery into the management of ovarian cancer after neoadjuvant chemotherapy

Incorporating robotic surgery into the management of ovarian cancer after neoadjuvant chemotherapy

... (p=0.6). All patients selected to undergo interval robotic cytoreduction following neoadjuvant chemotherapy had a reduction of cancer antigen 125 by at least 80%, resolution of ascites, and CT findings suggesting the ...

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