Rex, T.
Human T-Cell Leukemia Virus Type 2 Rex Carboxy Terminus Is an Inhibitory/Stability Domain That Regulates Rex Functional Activity and Viral Replication
... carboxy-terminal Rex-2 phosphorylation do- main and to address whether the ability to regulate Rex func- tion is important for HTLV-2-mediated cellular proliferation and immortalization in vitro and virus ...
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Human T-Cell Leukemia Virus Type 2 Rex Protein Increases Stability and Promotes Nuclear to Cytoplasmic Transport of gag/pol and env RNAs
... of Rex on steady-state levels of gag/pol, env, and tax/rex ...human T cells was analyzed by RT-PCR ...the rex mutant clone was distinct from that of the wild-type clone. The rex mutant ...
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T REx: A Large Scale Alignment of Natural Language with Knowledge Base Triples
... build T-REx, a large scale alignment dataset between free text documents and KB ...triples. T- REx consists of ...predicates. T-REx is two orders of mag- nitude larger than the ...
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Human T-Cell Leukemia Virus Type 1 Expressing Nonoverlapping Tax and Rex Genes Replicates and Immortalizes Primary Human T Lymphocytes but Fails To Replicate and Persist In Vivo
... and Rex are two regulatory proteins that are essential for HTLV replication ...or Rex mutants with defective activities or impaired biochemical properties that are associated with protein ...human T ...
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Phosphorylation regulates human T cell leukemia virus type 1 Rex function
... of Rex-1 ...analyzed Rex-1 protein derived from a different cell type (COS-7 or HTLV- 1 transformed T-cell lines), which may produce alterna- tive post-translational modification patterns when com- ...
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Phosphorylation of Two Serine Residues Regulates Human T-Cell Leukemia Virus Type 2 Rex Function
... human T-cell leukemia virus (HTLV) Rex phosphoprotein is to increase the level of the viral structural and enzymatic gene products expressed from the incompletely spliced viral RNAs containing the ...
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The human T-cell leukemia virus type 1 Rex regulatory protein exhibits an impaired functionality in human lymphoblastoid Jurkat T cells.
... 1 T-cell tropism of HTLV-1 is determined mainly at a postpenetration step of the retrovirus life cycle ...CEM T cells were unable to sustain a productive infection after coculture with irradiated HTLV-1- ...
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Inhibition of human T-cell leukemia virus type 2 Rex function by truncated forms of Rex encoded in alternatively spliced mRNAs.
... human T-cell leukemia virus type 2 (HTLV-2)-infected ...regulator Rex; shorter 1-3 and 1-B mRNAs encode a family of x-III proteins of unknown function that represent truncated forms of ...between Rex ...
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Nuclear Export and Expression of Human T-Cell Leukemia Virus Type 1 tax/rex mRNA Are RxRE/Rex Dependent
... Human T-cell leukemia virus type 1 (HTLV-1) is a complex retrovirus associated with the lymphoproliferative disease adult T- cell leukemia/lymphoma (ATL) and the neurodegenerative disorder tropical spastic ...
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Site-Specific Phosphorylation Regulates Human T-Cell Leukemia Virus Type 2 Rex Function In Vivo
... Human T-cell leukemia virus type 2 (HTLV-2) Rex is a transacting regulatory protein required for efficient cytoplasmic expression of the unspliced and incompletely spliced viral mRNA transcripts encoding ...
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Src family kinases interfere with dimerization of STAT5A through a phosphotyrosine-SH2 domain interaction
... HeLa T-REx HA-EpoR cells stably transfected with STAT5A-eYFP were stimulated with 1 U/ml Epo for 30 min and the localization of STAT5A-eYFP was analyzed by confocal ...HeLa T-REx vSrc-dsRed ...
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Expression of Alternatively Spliced Human T-Cell Leukemia Virus Type 1 mRNAs Is Influenced by Mitosis and by a Novel cis-Acting Regulatory Sequence
... for Rex function due to a mutation of codon 112 of Rex generating a stop codon (*) in exon ...of Rex and Tax (see boxes with gray lines) ...The Rex-independent tax/rex and p21rex mRNAs ...
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A library of mammalian effector modules for synthetic morphology
... selection, T-REx-293 cells stably trans- fected with pTREx-TGFP-2A-Cdh1 expressed mouse E- cadherin after 48 h of 1 μg/mL tetracycline induction, as shown by RT-PCR analysis (Figure ...and ...
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Quantitative Expression and Virus Transmission Analysis of DC-SIGN on Monocyte-Derived Dendritic Cells
... 293 T-REX ...assay. T-REX cells were seeded in 96-well plates, induced with doxycycline to express the respective lectins, and preincubated with the MAbs as described ...
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Expansion of Gamma Delta T Cells - A Short Review on Bisphosphonate and K562-Based Methods
... Vγ9Vδ2 T cell from the general PBMC population by ZOL and IL-2 as compared to cell ...Vγ9Vδ2 T cell has been well-validated and requires the presence of accessory cells such as monocytes and other MHC class ...
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Anti-Rex Aptamers as Mimics of the Rex-Binding Element
... to Rex, while 7% of the population from the fourth round of selection could bind Rex, as could 13% from the eighth round of ...bind Rex almost ninefold better than the wild-type ...
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Detection of human T cell lymphotropic virus type I proviral DNA and its gene expression in synovial cells in chronic inflammatory arthropathy
... associated chronic inflammatory arthropathy (HAAP), we sought to detect proviral DNA in the articular lesions. For the detection of proviral DNA, we used the polymerase chain reaction (PCR). Proviral DNA was detected not ...
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