RNA-binding motif 4
The impact of RNA binding motif protein 4-regulated splicing cascade on the progression and metabolism of colorectal cancer cells
... the RNA-binding motif 4 (RBM4) protein expression, leading to the imbalanced expression of the neuronal polypyrimidine tract-binding (nPTB) protein through alternative splicing-coupled ...
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Evaluation of RNA binding motif protein 3 expression in urothelial carcinoma of the bladder: an immunohistochemical study
... The literature concerning the exact role of RBM3 in carcinogenesis has so far been conflicting. RBM3 is a hypothermia-induced protein [3, 8–10] that has been found to assist in mRNA stability [12] and to increase ...
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RNA-Binding Motif Protein 24 (RBM24) Is Involved in Pregenomic RNA Packaging by Mediating Interaction between Hepatitis B Virus Polymerase and the Epsilon Element
... by binding to Pol and , suggesting that RBM24 may be incorporated into viral ...(lines 4 and 5) or 100 g of HepG2 cell lysates (lines 4 and 5) was digested with or without proteinase K, and the ...
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Decreased expression of RNA-binding motif protein 3 correlates with tumour progression and poor prognosis in urothelial bladder cancer
... RBM3 antibody AAb030038 (Atlas Antibodies AB, Stockholm, Sweden) diluted 1:10000. The specificity of the antibody has been validated previously [6,10], also in the human bladder cancer cell line RT-4, in which ...
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Zygotic Expression of the Double-Stranded RNA Binding Motif Protein Drb2p Is Required for DNA Elimination in the Ciliate Tetrahymena thermophila
... Upon initial recognition that the T. thermophila genome encodes two DSRM-containing proteins, we looked for evi- dence that would connect them as protein partners for the Dicer homologues encoded by DCL1 and DCR2 (42, ...
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Mutation of a C-Terminal Motif Affects Kaposi's Sarcoma-Associated Herpesvirus ORF57 RNA Binding, Nuclear Trafficking, and Multimerization
... RGG2 motif, instead of a site-directed mutant used herein, suggested that deletion of the RGG2 does not affect homodimerization ...57RGG2 motif in ORF57 ho- modimerization, coimmunoprecipitations were ...
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A Nucleotide Binding Motif in Hepatitis C Virus (HCV) NS4B Mediates HCV RNA Replication
... A motif consensus ...GTP binding assays were ...GTP binding on average compared to the wild- type NS4B-GFP protein (lanes 10 and 9 versus ...GTP binding activity to a lesser degree (lanes 11 ...
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Original Article The molecular responses of human embryonic kidney cells to abnormal expression of RNA binding motif protein 10: cues to molecular mechanism and function
... The RNA-binding motif protein 10 encoded by the RBM10 gene, contains two RNA recognition motifs, two zinc fingers and one G patch motif ...in RNA-binding pro- teins which ...
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Podocalyxin-like and RNA-binding motif protein 3 are prognostic biomarkers in urothelial bladder cancer: a validatory study
... its binding to RNA and modulation of RNA expression, making cells more genetically stable, or to the correlation between downregulation of RBM3 and reduced sensitivity to cisplatin in epithe- lial ...
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Identification and Molecular Characterization of the RNA Polymerase-Binding Motif of Infectious Bursal Disease Virus Inner Capsid Protein VP3
... vitro binding assays were performed by mixing a constant amount of the extract containing VP1 and the volume of extract, containing polyprotein deletion mutants or GFP fusion proteins, required to reach equivalent ...
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The RGG box motif of the herpes simplex virus ICP27 protein mediates an RNA-binding activity and determines in vivo methylation.
... to immunoprecipitation. To confirm that the ICP27 mutant proteins were expressed and immunoprecipitated, the samples were first subjected to Western blot analysis (Fig. 7B). With one exception, all of the mutant proteins ...
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An RNA aptamer targets the PDZ-binding motif of the HPV16 E6 oncoprotein.
... PDZ-domain-binding motif (ETQV) [16] which sometimes results in proteasome-induced degradation of the targeted ...to RNA [21], possibly playing role in RNA splicing ...
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The Circadian RNA-Binding Protein CHLAMY 1 Represents a Novel Type Heteromer of RNA Recognition Motif and Lysine Homology Domain-Containing Subunits
... Since the C3 subunit of C. reinhardtii interacts with another protein and can be found in a protein complex, we wanted to check if the mammalian C3 homologue in the brain would also be a part of a protein complex there. ...
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RNA motif discovery: a computational overview
... selected RNA, like the SELEX data ...single-stranded RNA that specifically bind to a target ligand locally owing to the existence of a common motif among the ...
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Genome-wide identification of grain filling genes regulated by the OsSMF1 transcription factor in rice
... three binding motifs, namely the GCN4 [TGA(G/C)TCA], ACGT [CCACGT(G/C)], and ATGA (GGATGAC) mo- tifs, with different ...GCN4 motif; ONAC024 and ONAC026, which contain either the GCN4 or ACGT motifs; and ...
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A Stem-Loop Motif Formed by the Immediate 5′ Terminus of the Bovine Viral Diarrhea Virus Genome Modulates Translation as well as Replication of the Viral RNA
... positive-stranded RNA genome which consists of a single open reading frame (ORF) and untranslated regions (UTRs) at the 5 ⴕ and 3 ⴕ ...extensive RNA structure motifs; most of them were shown to contribute ...
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Structural Phosphoprotein M2-1 of the Human Respiratory Syncytial Virus Is an RNA Binding Protein
... for RNA binding capacity in Northern-Western assays showed that all were able to bind long RNAs ...of RNA binding ca- pacities of different amounts of unphosphorylated and phos- phorylated ...
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Multiple maternal proteins coordinate to restrict the translation of C elegans nanos 2 to primordial germ cells
... Members of the nanos gene family are the evolutionarily conserved regulators of germ cell development (Kobayashi et al., 1996; Forbes and Lehmann, 1998; Subramaniam and Seydoux, 1999; Koprunner et al., 2001; Tsuda et ...
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Coagulase and Efb of Staphylococcus aureus Have a Common Fibrinogen Binding Motif
... Fg binding activities of these peptides were then investigated in a competition ELISA in which the binding of the Coa-C protein to Fg-coated microtiter wells was determined in the presence of increasing ...
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Rat lung contains a developmentally regulated manganese superoxide dismutase mRNA binding protein
... catalase RNA-binding protein was recently reported (Clerch, ...(MnSOD) RNA-binding proteins exist, we tested whether protein in rat lung extract would bind to 32P-labeled MnSOD ...MnSOD ...
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