scaffolding protein
Autoregulation of the bacteriophage P22 scaffolding protein gene.
... However, scaffolding protein gene autoregulation is analogous to these autoregulatory systems in that scaffolding protein molecules interact with the coat protein to form proheads, and a[r] ...
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Regions of the Herpes Simplex Virus Scaffolding Protein That Are Important for Intermolecular Self-Interaction
... (HSV-1) scaffolding protein encoded by gene ...capsid protein VP5 and through intermolecular interactions with ...minor protein, form a spherical structure which is broken down and released ...
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The scaffolding protein CG NAP/AKAP450 is a critical integrating component of the LFA 1 induced signaling complex in migratory T cells
... anchoring protein (AKAP) family of giant scaffolding proteins can assemble and compartmentalize multiple signaling and structural molecules thereby providing a platform for their targeted positioning and ...
8
Telomere protein Rap1 is a charge resistant scaffolding protein in chromosomal bouquet formation
... Rap1 protein revealed that it is pro- gressively phosphorylated throughout meiotic prophase and the number of phosphosites peaks after completion of the bouquet ...and protein interaction studies of the ...
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Identification of an Interacting Coat-External Scaffolding Protein Domain Required for both the Initiation of φX174 Procapsid Morphogenesis and the Completion of DNA Packaging
... external scaffolding proteins suggest that ␣ -helix 1 may act as a substrate specificity domain, mediating the initial coat scaffolding protein recognition in a species-specific ...external ...
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Identification of a minimal hydrophobic domain in the herpes simplex virus type 1 scaffolding protein which is required for interaction with the major capsid protein.
... for scaffolding protein ICP35 (33, ...the scaffolding protein is much more abun- dant ( ; 1,100 copies) in the capsids than the protease ( ; 100 copies) (38, ...the scaffolding ...
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Second-site suppressors of a cold-sensitive external scaffolding protein of bacteriophage phi X174.
... Isolation of second-site suppressors of a cs exter- nal scaffolding protein: All of the second-site sup- pressors, except one, conferred amino acid substitu- tions in [r] ...
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Highly Specific Salt Bridges Govern Bacteriophage P22 Icosahedral Capsid Assembly: Identification of the Site in Coat Protein Responsible for Interaction with Scaffolding Protein
... P22’s scaffolding proteins have similar folds, with the secondary structure being predominantly ...phi29 scaffolding protein can be superim- posed nicely onto P22’s C ...coat protein ...
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Assembly-controlled autogenous modulation of bacteriophage P22 scaffolding protein gene expression.
... The experiments presented here show that i the amount of unassembled scaffolding protein in wild-type P22-infected cells at various times after infection or in various P22 mutant-infecte[r] ...
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Identification of a Region in the Herpes Simplex Virus Scaffolding Protein Required for Interaction with the Portal
... the scaffolding protein in portal ...the scaffolding protein and the portal has also been identified biochemically, and observations suggest the interaction plays an important role in the ...
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From Resistance to Stimulation: the Evolution of a Virus in the Presence of a Dominant Lethal Inhibitory Scaffolding Protein
... external scaffolding protein that blocks X174 assembly, we previously demonstrated that such mechanisms are ...coat protein, whereas the fourth mutation alters the virus-encoded external ...
5
RACK1, A multifaceted scaffolding protein: Structure and function
... homology 2 (SH2) domain of Src Family protein tyro- sine kinases (Src-family PTKs). The recruitment of Src- family PTKs to FAK is dependent on the initial autop- hosphorylation of Tyr-397 and results in the ...
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Putting oesophageal cancer on the RACK A study of the RACK1 scaffolding protein in oesophageal adenocarcinoma
... RACK1 protein expression through a NF- κ B mediated induction of RACK1 gene ...RACK1 protein levels in SKGT-4 and FLO-1 OAC cells (Figure ...RACK1 protein levels as opposed to its effects on mere ...
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STIP is a critical nuclear scaffolding protein linking USP7 to p53-Mdm2 pathway regulation
... We now report the identification of a novel molecular function of STIP that links USP7 to the p53-Mdm2 pathway. We found that STIP and USP7 interact and colocalize in the native nuclear compartment. Overexpression of ...
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A new mode of SAM domain mediated oligomerization observed in the CASKIN2 neuronal scaffolding protein
... The tail surface is comprised of residues from the be- ginning of helix 5. Within helix 5, a glycine plays a crit- ical role because the absence of a side chain at this position permits the close approach of the helix ...
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Biochemical and pharmacological characterisation of the interaction between nMDA receptors and the scaffolding protein, PSD-95
... of protein tyrosine kinases and phosphatases was reported (Tezuka et ai, 1999; Kawachi et a l, 1999 ...by protein kinase ...endogenous protein kinases or phosphatases to the receptor complex and ...
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Posttranscriptional modulation of bacteriophage P22 scaffolding protein gene expression.
... If the gene 5 mRNA increased in functional stability with time after infection, then the coat protein should have been made at higher rate, relative to the other late proteins, at late t[r] ...
7
Coat Protein Mutations That Alter the Flux of Morphogenetic Intermediates through the ϕX174 Early Assembly Pathway
... mutant protein level, rescue was driven by concentration disparities between the two coat protein ...coat protein level, rescue would indicate that the mutations are indeed ...wild-type ...
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Comparative Genomic Studies of hypothetical proteins in Cyanophages
... capsid scaffolding protein (GPO) serine peptidase ; SlyX ; Baculovirus polyhedron envelope protein, PEP, C terminus ; FlgN protein ; Prominin ; Tat binding protein 1(TBP-1)-interacting ...
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Elevated Gab2 induces tumor growth and angiogenesis in colorectal cancer through upregulating VEGF levels
... a scaffolding protein acting downstream of both EGFR and VEGF, which mediates several intra- cellular pathways, such as AKT, ERK and signal trans- ducer and activator of transcription-3 (STAT3) signaling ...
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