shows the distribution of phenotypes and gene
Comprehensive Cancer-Predisposition Gene Testing in an Adult Multiple Primary Tumor Series Shows a Broad Range of Deleterious Variants and Atypical Tumor Phenotypes.
... Human Gene Mutation Database ...any gene) deemed pathogenic according to the criteria described ...the gene list would not be extracted from the original VCF files because their SO consequence would ...
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Distribution of Haptoglobin Phenotypes among Sudanese Leukemic patients
... Hp1 gene and the Hp1-1 phenotype among patients with AML, CML, and ALL (7, 16, 17) could not be confirmed in this study, since no significant differences were found in the ...
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Incorporating Gene Annotation into Genomic Prediction of Complex Phenotypes
... for gene locations when defining haplo- blocks can improve the predictive ability, using intralocus additive or categorical ...EjGA shows the highest predictive ability on ...
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Single nucleotide polymorphism gene intermixed networking reveals co linkers connected to multiple gene expression phenotypes
... We used the averaged correlation coefficient between co- linked genes as their co-expression measure. Table 2 lists the results for the top 1% SNP co-linkers, and the p-values correspond to the empirical values derived ...
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Association of the C825T polymorphism in the GNB3 gene with obesity and metabolic phenotypes in a Taiwanese population
... Siffert W, Forster P, Jo¨ckel KH, Mvere DA, Brinkmann B, Naber C, Crookes R, Du P, Heyns A, Epplen JT, Fridey J, Freedman BI, Mu¨ller N, Stolke D, Sharma AM, Al Moutaery K, Grosse-Wilde H, Buerbaum B, Ehrlich T, Ahmad ...
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The influence of disease categories on gene candidate predictions from model organism phenotypes
... a gene that is associated to a disease in MorbidMap or ...a gene that is not mentioned in MorbidMap or Orphanet for a particular disease counts as false ...that gene-disease associations may be ...
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Gene Clustering Based on RNAi Phenotypes of Ovary-Enriched Genes in C. elegans
... 3. Gene Cluster Display Based on RNAi-Induced Phenotypes in the Early Embryo (A) A cladogram of 161 GenePairs derived with 47 phenotypic ...corresponding gene name is also ...the distribution ...
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Simulating cyanobacterial phenotypes by integrating flux balance analysis, kinetics, and a light distribution function
... analysis shows that the Calvin cycle and the OPP pathway may function in complementary ways in photoautotrophs, since an active OPP pathway ensures a maintainable flux to triose phosphate synthesis from ...
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'CFTR-opathies': disease phenotypes associated with cystic fibrosis transmembrane regulator gene mutations
... CFTR gene), on the other ...the distribution of radiographic changes often involve the upper lobe, and mucoid Pseudomonas aeruginosa may be present in the lower ...
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Integromic analysis of genetic variation and gene expression identifies networks for cardiovascular disease phenotypes
... latory elements including DNase I hypersensitive regions profiled in 82 cell lines, 149 transcription factor (TF) binding regions profiled in dif- ferent cell lines resulting in a total of 406 different cell line–TF ...
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Cellular Werner Phenotypes in Mice Expressing a Putative Dominant-Negative Human WRN Gene
... size distribution assays, statistical compar- mented with 50 units/ml of penicillin, 50 mg/ml of streptomy- isons between genotypes were made using t -tests comparing cin, and 10% FBS that was heat-inactivated at ...
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Zebrafish knockout of Down syndrome gene, DYRK1A, shows social impairments relevant to autism
... ASD phenotypes. The DYRK1A gene is well conserved in vertebrates, in- cluding fish, rodents, and ...like phenotypes, yet the fish were viable without embry- onic ...
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Genotyping of the BCL2 Gene Polymorphism rs Shows Associations with Eukemia Tendencies in the Iraqi Population
... BCL2 Gene Polymorphism rs2279115 Shows Associations with Eukemia Tendencies in the Iraqi Population, J Pure Appl ...sharing, distribution, and reproduction in any medium, provided you give ...
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Identification of multiple gene-gene interactions for ordinal phenotypes
... Via a certain criterion based on GCVC K , multiple candi- dates of causal gene-gene interactions with the same order can be reported along with their performance measures (e.g., predictability for training ...
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The SLC6A14 gene shows evidence of association with obesity
... to hypothesize that allelic variants of the same gene may predispose to both traits. Acknowledgments We wish to warmly thank the patients for participating in this study. Teppo Varilo is greatly appreciated for ...
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The Psychosis Susceptibility gene ZNF804A: associations, functions and phenotypes
... 3. Kirov G, Zaharieva I, Georgieva L, Moskvina V, Nikolov I, Cichon S, Hillmer A, Toncheva D, Owen MJ, O'Donovan MC. A genome-wide association study in 574 schizophrenia trios using DNA pooling. Mol Psychiatry. 2009 ...
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The psychosis susceptibility gene ZNF804A: associations, functions, and phenotypes
... ‘‘better’’ cognitive performance than nonrisk allele car- riers in patients but not healthy controls. Of note, the cognitive functions involved—working memory and episodic memory—implicate precisely those cortical ...
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Linking gene expression to phenotypes via pathway information
... Keywords: Phenotypes, Pathways, Gene expression, Ontologies Introduction A fundamental aspect of disease research involves the understanding of biological processes that underpin observed ...measured ...
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The inset shows the result of a calculation of the angular distribution of radiation of a single
... The ultimate goal for biological applications of SMWFM is the observation of single molecules within living cells. The main obstacle on the route to achieving this goal is the autofluor- escence of cellular compartments. ...
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Targeting Gene-Viro-Therapy with AFP driving Apoptin gene shows potent antitumor effect in hepatocarcinoma
... kDa gene which control the viral mRNA trans- port ...E1A gene to treat hepatocellular ...E1A gene [8,10] or directly drive suicide genes such as herpes simplex virus thymidine kinase (HSV-tk) ...
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