Significantly differentially expressed detoxification genes with
Identification of aberrantly methylated differentially expressed genes targeted by differentially expressed miRNA in osteosarcoma
... key genes To further validate the impact of methylation on the expression of the TSGs, we treated MG63 cells with the methyltransferase inhibitor 5-Aza, and examined the expression levels of the relevant ...were ...
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Pomelo II: Finding differentially expressed genes
... regulated genes in each two- class comparison and their intersection ...of genes that are up regulated in both the contrast between classes 0 and 1 and the contrast between ...
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Statistical methods for ranking differentially expressed genes
... of genes that are falsely declared positive and the number of genes falsely declared negative by optimizing over a range of values of the significance level a and the fudge constant S 0 ...negatives ...
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IDENTIFICATION OF DIFFERENTIALLY EXPRESSED GENES USING BI CLUSTERING
... the genes into homogeneous clusters they are differentially expressed and non-differentially obtained from various clustering techniques for different data ...selecting differentially ...
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Identification of Differentially Expressed Genes in Papillary Thyroid Cancers
... specific genes, including tumor suppressor genes, oncogenes, apoptosis-associated genes and other predisposing ...However, genes, signaling pathways, and other basic mechanisms are cur- rently ...
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Detection of differentially expressed genes involved in osteoarthritis pathology
... TWIST1 can regulate FOS expression in the transcrip- tional regulatory network, and TWIST1 and FOS interact with each other in the PPI network. Kinne et al. found that compared to patients with OA or normal joints, c-fos ...
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Analysis of Differentially Expressed Genes in Neuroendocrine Carcinomas of the Lung
... ingly, areas with NE morphology did not show positive reaction for anti-NNAT antibody (Figure 2a). As for the three general NE markers—CGA, SYN and CD56 —10 LCNECs expressed multiple general NE markers; four ...
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Aberrantly methylated-differentially expressed genes and pathways in colorectal cancer
... methylated-differentially expressed genes and pathways in CRC by joint bioinformatics analysis of both gene expression and gene methylation microarrays, which may contribute to the finding of ...
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Microarray analysis of differentially expressed genes in the brains of tubby mice.
... Obesity with hyperphagia and insulin resistance was re- cently reported in Cck2r deficient mice (Clerc et al., 2007). However, mechanisms of hyperphagia and obesity in Cck2r deficient mice are not fully elucidated. ...
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Evaluation of Some Statistical Methods for the Identification of Differentially Expressed Genes
... The focus of the present study is a comparison of the top performing and popular methods SAM, samroc, rank product, and fold change along with modified versions of the SAM method and the fold change rule. As it is ...
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Differentially expressed genes between systemic sclerosis and rheumatoid arthritis
... core genes and pathways that differentiate SSc and ...up-regulated genes in SSc were related to extracellular activities, whereas the down-regulated genes were mainly related to immune ...
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Statistical Tests for Identification of Differentially Expressed Genes in Microarray Data
... experiments, differentially expressed genes, or discriminator genes, are the genes with considerably different expression patterns in two user-defined ...of genes, and which ...
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Chilling susceptibility in mungbean varieties is associated with their differentially expressed genes
... bility to stress, serve as good materials for uncovering how they differ in chilling tolerance. This study aimed to identify the ultrastructural, physiological and molecular changes to provide new insights on the ...
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Identification of Differentially Expressed Genes with Artificial Components the acde Package
... regulated genes (green) lie at the origin of the artificial plane so they have low or zero expression levels in all replicates 5 ...defence genes that would normally have low expression levels but become ...
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Verification of genes differentially expressed in neuroblastoma tumours: a study of potential tumour suppressor genes
... of genes that are seemingly downregulated in unfavourable tumours, ...as differentially expressed in NB tumours in several independent research studies [14,15,18,31-36] (Table ...12 genes ...
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Microarray data quality control improves the detection of differentially expressed genes
... of differentially expressed genes for the type I ...4000 genes to be differentially expressed between the two biological ...
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ORdensity: user-friendly R package to identify differentially expressed genes
... of genes, different numbers of cores and different number of permutations used in the bootstrap ...107 genes as potential DEGs and clustered them in two clusters with 83 and 24 genes ...of ...
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Identification of Differentially-expressed Genes in Intestinal Gastric Cancer by Microarray Analysis
... In this study, we performed a 22 K oligonucleotide micro- array analysis on 20 intestinal GC tissue samples and 20 NATs adjacent to tumors of intestinal GC in comparison with the five normal samples, respectively. Gene ...
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Tool for the identification of differentially expressed genes using a user-defined threshold
... making sense of the gene expression patterns which result from differing experiments. Detecting considerable increases or decreases in mRNA expression between experiments may lead to the discovery of significant ...
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Statistical methods for identifying differentially expressed genes in RNA-Seq experiments
... step, genes are classified into two exclusive classes, genes with or without over-dispersion, by using an adjusted score test on the hypothesis of whether or not the over-dispersion is present within the ...
8