Single cell measurements suggest stochastic changes
Single cell transcriptomics suggest that human adipocyte progenitor cells constitute a homogeneous cell population
... unbiased single cell transcriptomics we aimed to characterize ASC populations in human subcutaneous white adipose tissue ...574 single cells from the WAT total stroma vascular fraction (SVF) of four ...
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Automated cell cycle and cell size measurements for single cell gene expression studies
... each single cell, we measured the size, the posi- tion in the cell cycle and the mRNA ...among single cell volumes or cell cycle: all p-values were above the 5% ...neither ...
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A stochastic transcriptional switch model for single cell imaging data
... (a) (b) Fig. 2. Fluorescent time course data of 15 randomly selected cells from (a) an immature (post-natal day 1.5) rat pituitary tissue slice and (b) a mature (adult male) rat pituitary slice. Measurements were ...
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Single cell resolution of morphological changes in hemogenic endothelium
... observed changes could be due to activation of inflammatory pathways in ...that changes in RUNX1 and SOX17 protein levels mirror those seen in the murine system, strongly suggest that similar ...
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Estimating intrinsic and extrinsic noise from single-cell gene expression measurements
... is stochastic and displays variation (“noise”) both within and between ...a single cell,” Science, 297, ...a single cell,” Science, 297, ...
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Inferring the kinetics of stochastic gene expression from single cell RNA sequencing data
... modeling single-cell RNA-seq data and for studying the kinetics of stochastic gene ...using single-cell RNA-seq data generated from mouse ES ...results suggest that the chroma- ...
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Decoding the Regulatory Network for Blood Development from Single-Cell Gene Expression Measurements
... at single-cell ...that single-cell expression profiling coupled with computational approaches for network synthesis can reveal molecular control mechanisms of mammalian ...graded ...
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Beyond comparisons of means: understanding changes in gene expression at the single cell level
... whose cell-to-cell heterogeneity pattern changes between pre-specified populations of ...could suggest the existence of additional sub-groups within the analyzed ...
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Single Cell Tracking Reveals Antibiotic Induced Changes in Mycobacterial Energy Metabolism
... forms of M. tuberculosis have been implicated in bacteriological relapse following apparently eradicative chemotherapy (7). Here we have demonstrated some of the advantages of our method for real-time ...
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Aberrant placental immune parameters in the feline immunodeficiency virus (FIV) infected cat suggest virus induced changes in T cell function
... Cytokines such as IL-6, IL-1β, and TGF-β promote invasion Figure 2 Expression of cytokine genes in early term placental tissue from viable and nonviable offspring from control and infected queens. Real time qPCR was used ...
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Bayesian hierarchical stochastic inference on multiple, single cell, latent states from both longitudinal and stationary data
... a single cell ...two stochastic biological systems, both modelling transcrip- tional dynamics in single ...a stochastic system for protein populations where, for each cell, we ...
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A single cell based model for cell divisions with spontaneous topology changes
... properties, forces arising during division tend to minimize size differences between two daughter cells, which explains cellular topologies being similar to a random divi- sion scheme. Tissue growth based on Hertwig’s ...
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Linking single cell measurements of mass, growth rate, and gene expression
... transcriptional measurements suggested that all MDM2-inhibitor treated cells were actively ex- periencing drug but our biophysical measurements re- vealed mass and MAR heterogeneity, we decided to ...
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Stochastic single cell migration leads to robust horizontal cell layer formation in the vertebrate retina
... from single cell behaviour is not fully ...horizontal single cell behaviour from birth to final ...including cell cycle dynamics, migration paths and kinetics, as well as sister ...
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Single click beam patterns suggest dynamic changes to the field of view of echolocating Atlantic Spotted Dolphins (Stenella frontalis) in the wild
... Free-ranging Atlantic spotted dolphins may increase biosonar field of view at close range.. 272.[r] ...
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Single click beam patterns suggest dynamic changes to the field of view of echolocating Atlantic spotted dolphins (Stenella frontalis) in the wild
... prey changes rapidly, resulting in different biosonar requirements throughout prey pursuit and ...measured single-click beam patterns using a parametric fit procedure to test whether free-ranging Atlantic ...
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Dynamic single cell measurements of kinase activity by synthetic kinase activity relocation sensors
... the cell cycle stage ...correlate cell cycle stage with the dynamics of the SKARS, we tagged Whi5 and Yox1 with mCitrine in cells bearing the ...of cell cycle regulated genes induced in the M and G1 ...
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Early dynamic fate changes in haemogenic endothelium characterized at the single-cell level
... Fluorescent microscopy . Embryos were fixed in 4% paraformaldehyde (Electron Microscopy Sciences) for 1–2 h at 4 °C, washed in PBS, and soaked in 15% (w/v) sucrose for 2–4 h at 4 °C. Samples were snap-frozen in Tissue-Tek ...
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Reverse-engineering of gene networks for regulating early blood development from single-cell measurements
... the cell by using various types of omics datasets [1, ...the measurements using a population of ...including single-cell qPCR, single-cell RNA sequencing, and multiplex ...
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Single top quark measurements with CMS
... 2.1 Event selection In all analyses t-channel events, where the W-boson de- cays leptonically in either a muon or an electron and the corresponding neutrino are considered. The events are triggered with a single ...
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