Single chain
Retargeting of Adenovirus Vectors through Genetic Fusion of a Single-Chain or Single-Domain Antibody to Capsid Protein IX
... a single virus containing three different pIX isoforms displaying a FLAG tag, 6 ⫻ His tag, and mono- meric red fluorescent protein (RFP) ...a single-chain T-cell receptor targeted to MAGE-A1 antigen ...
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Paracrine Inhibition of Prion Propagation by Anti-PrP Single-Chain Fv Miniantibodies
... One possible solution to the latter problems is offered by the use of phage display-based single-chain miniantibodies (scFvs), which are small and consist of a single fusion polypeptide. ScFvs are ...
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Proteolytic properties of single chain factor XII: a mechanism for triggering contact activation
... that single-chain FXII has activity and that Poly-P enhances that activity toward the macromolecular substrates PK, FXII and ...for single chain FXII, compared with the activity for plasma ...
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The expression and metal affinity purification of single-chain antibodies
... The single-chain antibody could not be eluted from copper(II)-IDA-agarose using a pH gradient. It is generally accepted that proteins with histidines available for coordination bind copper more strongly ...
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Single-Chain Fv-Based Anti-HIV Proteins: Potential and Limitations
... The existence of very potent, broadly neutralizing antibodies against human immunodeficiency virus type 1 (HIV-1) offers the potential for prophylaxis against HIV-1 infection by passive immunization or gene therapy. Both ...
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Synthesis of sequence controlled multi block single chain nanoparticles by a step wise folding chain extension folding process
... polymeric single-chain microstructures attainable and provides new perspective to build complex ...one single sequence controlled polymer chain by a repeated “folding-chain exten- ...
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Use of Single-Chain Antibody Derivatives for Targeted Drug Delivery
... one single-chain bispecific diabody (scDb, containing the two scFvs together; Figure 3B) and evaluated their capacity in delivering liposome-encapsulated doxorubicin to the target cells ...bispecific ...
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Production of single chain Fab (scFab) fragments in Bacillus megaterium
... and Fab are produced in bacteria. The scFv format is com- posed of the variable regions of the antibody heavy (VH) and the light chain (VL) linked by a 15–25 amino acid linker [4,5]. ScFvs have the tendency to ...
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<p>Efficacy of a recombinant single-chain fragment variable region, VasSF, as a new drug for vasculitis</p>
... 23. Bonnard T, Tennant Z, Niego B, et al. Novel thrombolytic drug based on thrombin cleavable microplasminogen coupled to a single-chain antibody specific for activated GPIIb/IIIa. J Am Heart Assoc. ...
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Production and Evaluation of Specific Single-Chain Antibodies against CTLA-4 for Cancer-Targeted Therapy
... of single-chain antibodies (scFvs) compared to monoclonal antibodies in cancer immunotherapy, specific anti-CTLA-4 scFvs (single-chain variable fragment) were selected in this ...
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Transient and Stable Expression of Single-chain Antibody Fragment scFv13R4 in Chinese Hamster Ovary Cells.
... A single colony was picked using a pipette tip and cultured in 15 mL snap cap tubes (4 mL LB + 100 mg/mL Ampicillin), incubated overnight at 37 o C with vigorous shaking at 250 ...
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Cable properties and propagation velocity in a long single chain of simulated myocardial cells
... long single chains of 10, 20, 50, and 100 cells. The 100-cell chain is depicted in Figure ...100-cell chain (namely cell #51), and the fall-off of voltage was measured on both sides of the injected ...
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Advances in Fluorescent Single-Chain Nanoparticles
... Synthesis of fluorescent SCNPs upon intramolecular cross-linking via formation of fluorophore 318. triazole-benzene-triazole units ( a ), fluorescent SCNPs prepared from precursor pol[r] ...
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Advances in Single-Chain Nanoparticles for Catalysis Applications
... utilized to synthesize catalytic SCNPs based on metallo-folded polymer chains containing. 442[r] ...
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Cytomegalovirus assemblin: the amino and carboxyl domains of the proteinase form active enzyme when separately cloned and coexpressed in eukaryotic cells.
... their single-chain counterparts (48), the HCMV recom- binant two-chain enzyme cleaved SCMV pAP and the SCMV recombinant enzyme cleaved HCMV pAP, and both CMV two-chain assemblins cleaved HSV-1 ...
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A New Approach to Understanding Biological Control of Quinone Electrochemistry
... hydroquinone, semiquinone and oxidized states of their substrate quinones. This level of control allows for maximization of conversion efficiency between the energy of the quinone reducing equivalents and the proton ...
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EFFECT OF SPECIFIC TRAINING PROGRAMME ON DEFENSIVE ABILITY OF KHO KHO PLAYERS
... Pre-Single Chain was taken as ...of Single Chain of Specific Training Group and Control Group differ significantly when Pre- Single Chain was taken as ...of Single ...
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Structural and kinetic comparison of recombinant human single and two chain tissue plasminogen activator
... human single-chain tissue plasminogen activator (sct-PA) and two-chain tissue plasminogen activator (tct-PA), and compared these structural data with measurement of enzymatic ...
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Loose fit polypseudorotaxanes constructed from γ CDS and PHEMA PPG PEG PPG PHEMA
... give single-chain stranded, loose-fit PPRs or PRs (Jiang et ...polymer chain, a PPO-PEO- PPO, triblock copolymer was ...the chain end functionality and the efficiency of future chain ...
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The framework of image recognition based on modified freeman chain code
... Freeman chain code scheme (MFCC). The development of this chain code scheme is parallel with the development of the chain code ...Freeman chain code but with additional character started from ...
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