single-molecule
Theoretical Studies of Single Molecule Biophysical Systems and Photochemical Ensembles
... The differences in analyzing single molecule data will be described after the experimental conditions are described below. In the measured force-extension (F − x) curves of P5ab (14), there is a sudden drop ...
155
Geometric Phases in Single Molecule Magnets
... as Single Molecule Magnets (SMMs), see ...each molecule is a magnet in of itself as opposed to conventional bulk magnets that require long range magnetic ordering of their constituent magnetic dipole ...
71
Localization and abundance analysis of human lncRNAs at single cell and single molecule resolution
... Our first observation was that lncRNA FISH is prone to artifacts (likely owing to low abundance and repetitive nature of lncRNAs), and so we established a pipeline for rigorous validation of single molecule ...
16
The properties and applications of single molecule DNA sequencing
... Much longer reads, referred to as ‘strobe reads’ [39], can be generated by turning off the laser for periods of time during sequencing, which prevents premature termi nation caused by laser-induced photodamage to the ...
10
Heteroatom Induced Molecular Asymmetry Tunes Quantum Interference in Charge Transport through Single Molecule Junctions
... through single-molecule junctions with five-membered core ...of single- molecule ...through single-molecule ...in single-molecule electronics via ...
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Anchor Groups for Graphene Porphyrin Single Molecule Transistors
... 13 hypothesis: “All sets of data originate from the same statistical process”. If this p-value is lower than 0.05, we may discard the null-hypothesis. The statistical method used is described in the SI. When comparing ...
25
Nanomechanical and thermophoretic analyses of the nucleotide-dependent interactions between the AAA+ subunits of magnesium chelatase
... this single molecule approach yields the most probable unbinding force measured in ...linker molecule (SM(PEG) 24 , ∼ 10 nm length) terminated with Ni- NTA groups, (Figure ...the molecule on ...
7
Tunable magnetoresistance in an asymmetrically coupled single-molecule junction
... the single molecule level [2, 3] may enable novel spintronic devices ...a single molecule junction arising from nega- tive differential resistance that shifts in a magnetic field at a rate two ...
15
Electrochemical Single-Molecule Transistors with Optimized Gate Coupling
... Single-molecule electrochemical gating of viologen molecular bridges, studied here for the first time in ionic liquids, is very different from the behavior previously observed for aqueous electrolytes. In ...
29
Microfluidic deposition for resolving single molecule protein architecture and heterogeneity
... versatile single-molecule ana- lysis technique in biology, because it offers the opportu- nity of acquiring 3D morphological maps of specimens with subnanometer resolution, in both air and in liquid ...
12
Detecting a single molecule using a micropore nanopore hybrid chip
... conically-shaped single nanopore in polymer membranes (such as polycarbonate, poly(ethylene terephthalate), poly- propylene, poly-(vinylidene fluoride), and polyimide), which provides other possible choice for ...
7
Synthesis, characterisation and single molecule conductance measurements of organic molecules
... organic molecule could induce rectifier properties, in much the same way as a p-n type ...a molecule would behave in an analogous fashion to a p-n ...of single molecules in electronic devices, their ...
161
Single-molecule electronics: from chemical design to functional devices
... probe single molecule conductivity have improved during recent years, especially in terms of faster throughput, as well as the introduction of more complex devices ...identical single-molecule ...
34
Hybrid plasmonic waveguide coupling of photons from a single molecule
... a single optical mode and, like the micropillar, is not natu- rally compatible with a planar integrated ...a single molecule of diben- zoterrylene (DBT) in the plasmonic ...
8
Resolving the Complexity of Human Skin Metagenomes Using Single Molecule Sequencing
... With continuing cost reductions and performance advances in SMRT technology, long-read approaches are poised to contribute substantially to microbial community analysis. While SMRT reads reconstruct compositional ...
13
Single Molecule Thermodynamics Hypothesis of Protein Folding and Drug Design
... A single molecule view of protein folding leads to the concept of conforma- tional Gibbs free energy function G ( ; , ) X E U , where the variable X is a conformation of a protein U ...
9
Advances in single molecule nucleic acid sequencing
... directly reflected in the abundance of any particular sequence tag within the population of molecules and therefore offers a digital profiling of gene expression. Poisson statistics should apply to counting models using ...
164
Single molecule electronics in ionic liquid media
... a single molecule of BDT bridges the ...a single molecule was measured to be 45 ...a single molecule of BDT 14 , which is approximately 20 times larger than Reed et ...BDT ...
180
Single molecule detection and DNA sequencing by synthesis
... of single-molecule fluorescence were made by using a conventional microscope equipped with total internal reflection illumination (22), which reduces background fluorescence ...
165
Single-molecule studies of the dynamics and interactions of bacterial OXPHOS complexes
... 5 Renz et al 2015 [20] report PALM and single particle tracking (SPT) PALM imaging of the ATP synthase in live E. coli. This is an insightful study, but unfortunately the authors do not make clear how the PALM ...
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