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Sodium Deoxycholate

Hydrophobic ion pairing of an insulin-sodium deoxycholate complex for oral delivery of insulin

Hydrophobic ion pairing of an insulin-sodium deoxycholate complex for oral delivery of insulin

... Further, sodium deoxy- cholate can enhance the apparent liposolubility of insulin in the form of ...as sodium deoxycholate was slowly added to the insulin solution, the CE (%) increased gradually ...

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Effect of solvent composition on the critical micelle concentration of sodium deoxycholate in ethanol-water mixed solvent media

Effect of solvent composition on the critical micelle concentration of sodium deoxycholate in ethanol-water mixed solvent media

... of sodium deoxycholate in pure water and ethanol- water mixed solvent media containing ...of sodium deoxycholate decreases with the increase in the volume fraction of ...of sodium ...

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IN-VIVO ANTI-TUMOR EFFECT OF 5-FLUOROURACIL LOADED CHITOSAN-SODIUM DEOXYCHOLATE NANOPARTICLES

IN-VIVO ANTI-TUMOR EFFECT OF 5-FLUOROURACIL LOADED CHITOSAN-SODIUM DEOXYCHOLATE NANOPARTICLES

... [13,14] Sodium deoxycholate (DS) is one of the endogenous bile salts which could improve the paracellular transport of hydrophilic drugs if added to CS, the mechanism of sodium deoxycholate as ...

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In vitro cytotoxicity and transfection efficiency of pDNA encoded p53 gene-loaded chitosan-sodium deoxycholate nanoparticles

<p>In vitro cytotoxicity and transfection efficiency of pDNA encoded p53 gene-loaded chitosan-sodium deoxycholate nanoparticles</p>

... as sodium deoxycholate (DS), was shown to improve paracellular transport of hydrophilic drugs, where at a certain concentration, bile salts could form reverse micelles that include water mole- cules, thus ...

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Sodium deoxycholate-decorated zein nanoparticles for a stable colloidal drug delivery system

Sodium deoxycholate-decorated zein nanoparticles for a stable colloidal drug delivery system

... and sodium deoxycholate allowed us to obtain nanoparticles characterized by a mean diameter of 100–200 nm when a protein concentration of 2 mg/mL was ...using sodium deoxycholate ...The ...

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Ionic liquid as separation enhancer in thin-layer chromatography of biosurfactants: mutual separation of sodium cholate, sodium deoxycholate and sodium taurocholate

Ionic liquid as separation enhancer in thin-layer chromatography of biosurfactants: mutual separation of sodium cholate, sodium deoxycholate and sodium taurocholate

... anions, vitamins, amino acids and non-ionic surfactants as impurities) on the separation of surfactants was also examined. Effects of concentration level of 1-methylimidazolium chloride as impregnant and its substitution ...

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Mechanism of enhanced antiosteoporosis effect of&nbsp;circinal&ndash;icaritin by self-assembled nanomicelles&nbsp;in vivo with suet oil and sodium deoxycholate

Mechanism of enhanced antiosteoporosis effect of&nbsp;circinal&ndash;icaritin by self-assembled nanomicelles&nbsp;in vivo with suet oil and sodium deoxycholate

... Materials and methods: In this paper, suet oil (SO) was used to improve the oral bioavail- ability of CIT and enhance its antiosteoporosis effect and absorption. After oral administration of CIT together with SO, the CIT ...

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Simian virus 40 DNA extracted from infected cells with sodium deoxycholate no longer reflects its in vivo superhelix density.

Simian virus 40 DNA extracted from infected cells with sodium deoxycholate no longer reflects its in vivo superhelix density.

... SV40 DNA was incubated in the presence of increasing concentrations of DOC see below in 10 mM Tris- Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest When simian virus 40[r] ...

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Application of sodium deoxycholate for separation of heavy metals : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Environmental Engineering at Massey University, Palmerston North, New Zealand

Application of sodium deoxycholate for separation of heavy metals : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Environmental Engineering at Massey University, Palmerston North, New Zealand

... nickel deoxycholate aggregates are transported to the membrane ...nickel deoxycholate at 1 bar. In such a situation, some nickel deoxycholate precipitate may be re-dissolved and transported with the ...

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The impact of detergents on the tissue decellularization process: a ToF SIMS study

The impact of detergents on the tissue decellularization process: a ToF SIMS study

... differentiated urothelial tissues can be generated from normal human urothelial cells propagated in vitro [57, 59, 60]. Culture of human urothelial cells upon UBM scaffolds thus provided an ideal opportunity to assess ...

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Preparation, optimization, and in vitro simulated inhalation delivery of carvedilol nanoparticles loaded on a coarse carrier intended for pulmonary administration

Preparation, optimization, and in vitro simulated inhalation delivery of carvedilol nanoparticles loaded on a coarse carrier intended for pulmonary administration

... Therefore, this study aims to design and optimize stable CAR nanosuspensions adopting the antisolvent precipitation– ultrasonication method in order to improve drug dissolution rate, which will consequently enhance ...

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Enhanced transdermal permeability and drug deposition of rheumatoid arthritis via sinomenine hydrochloride-loaded antioxidant surface transethosome

<p>Enhanced transdermal permeability and drug deposition of rheumatoid arthritis via sinomenine hydrochloride-loaded antioxidant surface transethosome</p>

... 80, sodium deoxycholate, and oleic acid can be interca- lated between the lipid bilayer, leading to a decreased phase transition temperature of skin lipids, as well as an increase in their fl ...

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Transbuccal delivery of betahistine dihydrochloride from mucoadhesive tablets with a unidirectional drug flow: in vitro, ex vivo and in vivo evaluation

Transbuccal delivery of betahistine dihydrochloride from mucoadhesive tablets with a unidirectional drug flow: in vitro, ex vivo and in vivo evaluation

... Methods: A direct compression method was adopted for preparation of the tablets using mucoadhesive polymers like guar gum, hydroxypropyl methyl cellulose K4M, sodium carboxym- ethyl cellulose and their ...

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Ocular anti-inflammatory activity of prednisolone acetate loaded chitosan-deoxycholate self-assembled nanoparticles

<p>Ocular anti-inflammatory activity of prednisolone acetate loaded chitosan-deoxycholate self-assembled nanoparticles</p>

... Sodium deoxycholate (SD) is one of the bile salts classed as an endogenous surfactant. SD has been employed as an absorp- tion enhancer to increase drug transport across various biolo- gical barriers. ...

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Liposomes containing bile salts as novel ocular delivery systems for tacrolimus (FK506): in vitro characterization and improved corneal permeation

Liposomes containing bile salts as novel ocular delivery systems for tacrolimus (FK506): in vitro characterization and improved corneal permeation

... glycocholate, sodium taurocholate, and sodium deoxycholate) and tacrolimus were dissolved in dichloromethane/methanol (9:1, v/v) in a round-bottom ...

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Studies on the role of histones in the structure and function of chromatin

Studies on the role of histones in the structure and function of chromatin

... Thus, the template activity of chromatin samples partially dehistonized by increasing concentrations of sodium deoxycholate DOC or sodium chloride NaC1increeses from the template activit[r] ...

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Gram positive Streptococci

Gram positive Streptococci

... alpha-hemolytic streptococci (Viridans group) • Bile solubility test. – S pneumoniae lyses in a suspension of sodium deoxycholate while[r] ...

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Application of spray granulation for conversion of mixed phospholipid-bile salt micelles to dry powder form: influence of drug hydrophobicity on nanoparticle reagglomeration

Application of spray granulation for conversion of mixed phospholipid-bile salt micelles to dry powder form: influence of drug hydrophobicity on nanoparticle reagglomeration

... China); sodium deoxycholate (SDC) from Beijing Hotaibio Science and Technology Co, Ltd (Beijing, People’s Republic of China); hydroxypropyl methyl cellulose (HPMC) 5 mPa ⋅ s from Colorcon, Inc (Shanghai, ...

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AMBIsome Therapy Induction OptimisatioN (AMBITION): High Dose AmBisome for Cryptococcal Meningitis Induction Therapy in sub Saharan Africa: Study Protocol for a Phase 3 Randomised Controlled Non Inferiority Trial

AMBIsome Therapy Induction OptimisatioN (AMBITION): High Dose AmBisome for Cryptococcal Meningitis Induction Therapy in sub Saharan Africa: Study Protocol for a Phase 3 Randomised Controlled Non Inferiority Trial

... Written informed consent to enter the trial and be rando- mised will be obtained from participants or, in the case of those lacking capacity to consent, from next of kin with legal responsibility (if appropriate and in ...

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“Development and Validation of Stability Indicating UFLC Method for the Estimation of Cefotaxime Sodium and Diclofenac Sodium in Bulk and Pharmaceutical Dosage Forms” by Venkata Sairam Koganti, J Channabasappa Thejaswini, Ravandur Shivanna Chandan, Bannim

“Development and Validation of Stability Indicating UFLC Method for the Estimation of Cefotaxime Sodium and Diclofenac Sodium in Bulk and Pharmaceutical Dosage Forms” by Venkata Sairam Koganti, J Channabasappa Thejaswini, Ravandur Shivanna Chandan, Bannimath Gurupadayya, India.

... The combination of Cefotaxime sodium and Diclofenac sodium was selected for the current study. The wide literature survey carried out revealed that there is no method reported for the simultaneous ...

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